Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 124

1.

Comprehensive assay of kinase catalytic activity reveals features of kinase inhibitor selectivity.

Anastassiadis T, Deacon SW, Devarajan K, Ma H, Peterson JR.

Nat Biotechnol. 2011 Oct 30;29(11):1039-45. doi: 10.1038/nbt.2017.

2.

Comprehensive analysis of kinase inhibitor selectivity.

Davis MI, Hunt JP, Herrgard S, Ciceri P, Wodicka LM, Pallares G, Hocker M, Treiber DK, Zarrinkar PP.

Nat Biotechnol. 2011 Oct 30;29(11):1046-51. doi: 10.1038/nbt.1990.

PMID:
22037378
3.

Recent advances in designing substrate-competitive protein kinase inhibitors.

Han KC, Kim SY, Yang EG.

Curr Pharm Des. 2012;18(20):2875-82. Review.

PMID:
22571656
4.

The evolution of protein kinase inhibitors from antagonists to agonists of cellular signaling.

Dar AC, Shokat KM.

Annu Rev Biochem. 2011;80:769-95. doi: 10.1146/annurev-biochem-090308-173656. Review.

PMID:
21548788
5.

Bivalent inhibitors of protein kinases.

Gower CM, Chang ME, Maly DJ.

Crit Rev Biochem Mol Biol. 2014 Mar-Apr;49(2):102-15. doi: 10.3109/10409238.2013.875513. Epub 2014 Feb 25. Review.

7.

A broad activity screen in support of a chemogenomic map for kinase signalling research and drug discovery.

Gao Y, Davies SP, Augustin M, Woodward A, Patel UA, Kovelman R, Harvey KJ.

Biochem J. 2013 Apr 15;451(2):313-28. doi: 10.1042/BJ20121418.

PMID:
23398362
8.

Cross-reactivity virtual profiling of the human kinome by X-react(KIN): a chemical systems biology approach.

Brylinski M, Skolnick J.

Mol Pharm. 2010 Dec 6;7(6):2324-33. doi: 10.1021/mp1002976. Epub 2010 Nov 8.

9.

Unprecedently Large-Scale Kinase Inhibitor Set Enabling the Accurate Prediction of Compound-Kinase Activities: A Way toward Selective Promiscuity by Design?

Christmann-Franck S, van Westen GJ, Papadatos G, Beltran Escudie F, Roberts A, Overington JP, Domine D.

J Chem Inf Model. 2016 Sep 26;56(9):1654-75. doi: 10.1021/acs.jcim.6b00122. Epub 2016 Aug 11.

10.

Bioluminescent kinase strips: A novel approach to targeted and flexible kinase inhibitor profiling.

Hennek J, Alves J, Yao E, Goueli SA, Zegzouti H.

Anal Biochem. 2016 Feb 15;495:9-20. doi: 10.1016/j.ab.2015.11.007. Epub 2015 Nov 25.

11.

Profile-QSAR: a novel meta-QSAR method that combines activities across the kinase family to accurately predict affinity, selectivity, and cellular activity.

Martin E, Mukherjee P, Sullivan D, Jansen J.

J Chem Inf Model. 2011 Aug 22;51(8):1942-56. doi: 10.1021/ci1005004. Epub 2011 Jul 19.

PMID:
21667971
12.

A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.

Fedorov O, Marsden B, Pogacic V, Rellos P, Müller S, Bullock AN, Schwaller J, Sundström M, Knapp S.

Proc Natl Acad Sci U S A. 2007 Dec 18;104(51):20523-8. Epub 2007 Dec 11.

13.

KIDFamMap: a database of kinase-inhibitor-disease family maps for kinase inhibitor selectivity and binding mechanisms.

Chiu YY, Lin CT, Huang JW, Hsu KC, Tseng JH, You SR, Yang JM.

Nucleic Acids Res. 2013 Jan;41(Database issue):D430-40. doi: 10.1093/nar/gks1218. Epub 2012 Nov 28.

14.

Targeting protein kinases with selective and semipromiscuous covalent inhibitors.

Miller RM, Taunton J.

Methods Enzymol. 2014;548:93-116. doi: 10.1016/B978-0-12-397918-6.00004-5. Review.

15.

Selectivity assessment of kinase inhibitors: strategies and challenges.

Luo Y.

Curr Opin Mol Ther. 2005 Jun;7(3):251-5. Review.

PMID:
15977423
16.

Chemical proteomics and functional proteomics strategies for protein kinase inhibitor validation and protein kinase substrate identification: applications to protein kinase CK2.

Gyenis L, Turowec JP, Bretner M, Litchfield DW.

Biochim Biophys Acta. 2013 Jul;1834(7):1352-8. doi: 10.1016/j.bbapap.2013.02.006. Epub 2013 Feb 14. Review.

PMID:
23416530
17.

Integrating ligand-based and protein-centric virtual screening of kinase inhibitors using ensembles of multiple protein kinase genes and conformations.

Dixit A, Verkhivker GM.

J Chem Inf Model. 2012 Oct 22;52(10):2501-15. doi: 10.1021/ci3002638. Epub 2012 Oct 1.

PMID:
22992037
18.

Protein kinase inhibitors: structural insights into selectivity.

Thaimattam R, Banerjee R, Miglani R, Iqbal J.

Curr Pharm Des. 2007;13(27):2751-65. Review.

PMID:
17897021
19.

Small kinase assay panels can provide a measure of selectivity.

Brandt P, Jensen AJ, Nilsson J.

Bioorg Med Chem Lett. 2009 Oct 15;19(20):5861-3. doi: 10.1016/j.bmcl.2009.08.083. Epub 2009 Aug 27.

PMID:
19748779
20.

Protein kinase structure and function analysis with chemical tools.

Shen K, Hines AC, Schwarzer D, Pickin KA, Cole PA.

Biochim Biophys Acta. 2005 Dec 30;1754(1-2):65-78. Epub 2005 Sep 13. Review.

PMID:
16213197

Supplemental Content

Support Center