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Items: 1 to 20 of 221

1.

Analysis of RNA binding by the dengue virus NS5 RNA capping enzyme.

Henderson BR, Saeedi BJ, Campagnola G, Geiss BJ.

PLoS One. 2011;6(10):e25795. doi: 10.1371/journal.pone.0025795. Epub 2011 Oct 12.

2.

Construction of plasmid, bacterial expression, purification, and assay of dengue virus type 2 NS5 methyltransferase.

Boonyasuppayakorn S, Padmanabhan R.

Methods Mol Biol. 2014;1138:361-73. doi: 10.1007/978-1-4939-0348-1_22.

PMID:
24696348
3.

Recognition of RNA cap in the Wesselsbron virus NS5 methyltransferase domain: implications for RNA-capping mechanisms in Flavivirus.

Bollati M, Milani M, Mastrangelo E, Ricagno S, Tedeschi G, Nonnis S, Decroly E, Selisko B, de Lamballerie X, Coutard B, Canard B, Bolognesi M.

J Mol Biol. 2009 Jan 9;385(1):140-52. doi: 10.1016/j.jmb.2008.10.028. Epub 2008 Oct 19.

PMID:
18976670
4.

Structure and function of flavivirus NS5 methyltransferase.

Zhou Y, Ray D, Zhao Y, Dong H, Ren S, Li Z, Guo Y, Bernard KA, Shi PY, Li H.

J Virol. 2007 Apr;81(8):3891-903. Epub 2007 Jan 31.

5.

Structural and functional analysis of methylation and 5'-RNA sequence requirements of short capped RNAs by the methyltransferase domain of dengue virus NS5.

Egloff MP, Decroly E, Malet H, Selisko B, Benarroch D, Ferron F, Canard B.

J Mol Biol. 2007 Sep 21;372(3):723-36. Epub 2007 Jul 12.

PMID:
17686489
6.

Molecular basis for specific viral RNA recognition and 2'-O-ribose methylation by the dengue virus nonstructural protein 5 (NS5).

Zhao Y, Soh TS, Lim SP, Chung KY, Swaminathan K, Vasudevan SG, Shi PY, Lescar J, Luo D.

Proc Natl Acad Sci U S A. 2015 Dec 1;112(48):14834-9. doi: 10.1073/pnas.1514978112. Epub 2015 Nov 17.

7.

The flavivirus NS5 protein is a true RNA guanylyltransferase that catalyzes a two-step reaction to form the RNA cap structure.

Issur M, Geiss BJ, Bougie I, Picard-Jean F, Despins S, Mayette J, Hobdey SE, Bisaillon M.

RNA. 2009 Dec;15(12):2340-50. doi: 10.1261/rna.1609709. Epub 2009 Oct 22.

8.

A high-throughput screening assay for the identification of flavivirus NS5 capping enzyme GTP-binding inhibitors: implications for antiviral drug development.

Geiss BJ, Stahla-Beek HJ, Hannah AM, Gari HH, Henderson BR, Saeedi BJ, Keenan SM.

J Biomol Screen. 2011 Sep;16(8):852-61. doi: 10.1177/1087057111412183. Epub 2011 Jul 25.

9.

Mutagenesis of the dengue virus type 2 NS5 methyltransferase domain.

Kroschewski H, Lim SP, Butcher RE, Yap TL, Lescar J, Wright PJ, Vasudevan SG, Davidson AD.

J Biol Chem. 2008 Jul 11;283(28):19410-21. doi: 10.1074/jbc.M800613200. Epub 2008 May 9.

10.

2'-O methylation of internal adenosine by flavivirus NS5 methyltransferase.

Dong H, Chang DC, Hua MH, Lim SP, Chionh YH, Hia F, Lee YH, Kukkaro P, Lok SM, Dedon PC, Shi PY.

PLoS Pathog. 2012;8(4):e1002642. doi: 10.1371/journal.ppat.1002642. Epub 2012 Apr 5.

11.

Structure-based and ligand-based virtual screening of novel methyltransferase inhibitors of the dengue virus.

Lim SV, Rahman MB, Tejo BA.

BMC Bioinformatics. 2011;12 Suppl 13:S24. doi: 10.1186/1471-2105-12-S13-S24. Epub 2011 Nov 30.

12.

Development of specific dengue virus 2'-O- and N7-methyltransferase assays for antiviral drug screening.

Barral K, Sallamand C, Petzold C, Coutard B, Collet A, Thillier Y, Zimmermann J, Vasseur JJ, Canard B, Rohayem J, Debart F, Decroly E.

Antiviral Res. 2013 Sep;99(3):292-300. doi: 10.1016/j.antiviral.2013.06.001. Epub 2013 Jun 12.

PMID:
23769894
13.

Biochemical characterization of the (nucleoside-2'O)-methyltransferase activity of dengue virus protein NS5 using purified capped RNA oligonucleotides (7Me)GpppAC(n) and GpppAC(n).

Selisko B, Peyrane FF, Canard B, Alvarez K, Decroly E.

J Gen Virol. 2010 Jan;91(Pt 1):112-21. doi: 10.1099/vir.0.015511-0. Epub 2009 Sep 23.

PMID:
19776234
14.

Analysis of flavivirus NS5 methyltransferase cap binding.

Geiss BJ, Thompson AA, Andrews AJ, Sons RL, Gari HH, Keenan SM, Peersen OB.

J Mol Biol. 2009 Feb 6;385(5):1643-54. doi: 10.1016/j.jmb.2008.11.058. Epub 2008 Dec 11.

16.

Crystal structure of the dengue virus methyltransferase bound to a 5'-capped octameric RNA.

Yap LJ, Luo D, Chung KY, Lim SP, Bodenreider C, Noble C, Shi PY, Lescar J.

PLoS One. 2010 Sep 17;5(9). pii: e12836. doi: 10.1371/journal.pone.0012836.

17.

Flaviviral methyltransferase/RNA interaction: structural basis for enzyme inhibition.

Milani M, Mastrangelo E, Bollati M, Selisko B, Decroly E, Bouvet M, Canard B, Bolognesi M.

Antiviral Res. 2009 Jul;83(1):28-34. doi: 10.1016/j.antiviral.2009.03.001. Epub 2009 Mar 14.

PMID:
19501254
18.

Flavivirus methyltransferase: a novel antiviral target.

Dong H, Zhang B, Shi PY.

Antiviral Res. 2008 Oct;80(1):1-10. doi: 10.1016/j.antiviral.2008.05.003. Epub 2008 Jun 5. Review.

19.

Identification of a novel antiviral inhibitor of the flavivirus guanylyltransferase enzyme.

Stahla-Beek HJ, April DG, Saeedi BJ, Hannah AM, Keenan SM, Geiss BJ.

J Virol. 2012 Aug;86(16):8730-9. doi: 10.1128/JVI.00384-12. Epub 2012 Jun 6.

20.

The dengue virus NS5 protein as a target for drug discovery.

Lim SP, Noble CG, Shi PY.

Antiviral Res. 2015 Jul;119:57-67. doi: 10.1016/j.antiviral.2015.04.010. Epub 2015 Apr 24. Review.

PMID:
25912817

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