Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 145

1.

Protein arginine methyltransferase Prmt5-Mep50 methylates histones H2A and H4 and the histone chaperone nucleoplasmin in Xenopus laevis eggs.

Wilczek C, Chitta R, Woo E, Shabanowitz J, Chait BT, Hunt DF, Shechter D.

J Biol Chem. 2011 Dec 9;286(49):42221-31. doi: 10.1074/jbc.M111.303677. Epub 2011 Oct 18.

2.

Histone H2A and H4 N-terminal tails are positioned by the MEP50 WD repeat protein for efficient methylation by the PRMT5 arginine methyltransferase.

Burgos ES, Wilczek C, Onikubo T, Bonanno JB, Jansong J, Reimer U, Shechter D.

J Biol Chem. 2015 Apr 10;290(15):9674-89. doi: 10.1074/jbc.M115.636894. Epub 2015 Feb 24.

3.

Structure of the arginine methyltransferase PRMT5-MEP50 reveals a mechanism for substrate specificity.

Ho MC, Wilczek C, Bonanno JB, Xing L, Seznec J, Matsui T, Carter LG, Onikubo T, Kumar PR, Chan MK, Brenowitz M, Cheng RH, Reimer U, Almo SC, Shechter D.

PLoS One. 2013;8(2):e57008. doi: 10.1371/journal.pone.0057008. Epub 2013 Feb 25. Erratum in: PLoS One. 2013;8(8). doi:10.1371/annotation/e6b5348e-9052-4a3b-8f06-90d01dc88fc2.

4.

Phosphorylation and arginine methylation mark histone H2A prior to deposition during Xenopus laevis development.

Wang WL, Anderson LC, Nicklay JJ, Chen H, Gamble MJ, Shabanowitz J, Hunt DF, Shechter D.

Epigenetics Chromatin. 2014 Sep 6;7:22. doi: 10.1186/1756-8935-7-22. eCollection 2014.

5.

A TGFβ-PRMT5-MEP50 axis regulates cancer cell invasion through histone H3 and H4 arginine methylation coupled transcriptional activation and repression.

Chen H, Lorton B, Gupta V, Shechter D.

Oncogene. 2017 Jan 19;36(3):373-386. doi: 10.1038/onc.2016.205. Epub 2016 Jun 6.

6.

Nucleoplasmin-mediated unfolding of chromatin involves the displacement of linker-associated chromatin proteins.

Ramos I, Prado A, Finn RM, Muga A, Ausió J.

Biochemistry. 2005 Jun 14;44(23):8274-81.

PMID:
15938617
7.

MEP50/PRMT5 Reduces Gene Expression by Histone Arginine Methylation and this Is Reversed by PKCδ/p38δ Signaling.

Saha K, Adhikary G, Eckert RL.

J Invest Dermatol. 2016 Jan;136(1):214-24. doi: 10.1038/JID.2015.400.

9.

Methylosome Protein 50 and PKCδ/p38δ Protein Signaling Control Keratinocyte Proliferation via Opposing Effects on p21Cip1 Gene Expression.

Saha K, Eckert RL.

J Biol Chem. 2015 May 22;290(21):13521-30. doi: 10.1074/jbc.M115.642868. Epub 2015 Apr 7.

10.

Developmentally Regulated Post-translational Modification of Nucleoplasmin Controls Histone Sequestration and Deposition.

Onikubo T, Nicklay JJ, Xing L, Warren C, Anson B, Wang WL, Burgos ES, Ruff SE, Shabanowitz J, Cheng RH, Hunt DF, Shechter D.

Cell Rep. 2015 Mar 11. pii: S2211-1247(15)00196-5. doi: 10.1016/j.celrep.2015.02.038. [Epub ahead of print]

11.

Chromatin decondensation and nuclear reprogramming by nucleoplasmin.

Tamada H, Van Thuan N, Reed P, Nelson D, Katoku-Kikyo N, Wudel J, Wakayama T, Kikyo N.

Mol Cell Biol. 2006 Feb;26(4):1259-71. Erratum in: Mol Cell Biol. 2007 Sep;27(18):6580.

12.

Protein arginine methyltransferase 5 catalyzes substrate dimethylation in a distributive fashion.

Wang M, Fuhrmann J, Thompson PR.

Biochemistry. 2014 Dec 23;53(50):7884-92. doi: 10.1021/bi501279g. Epub 2014 Dec 8.

PMID:
25485739
13.

Human SWI/SNF-associated PRMT5 methylates histone H3 arginine 8 and negatively regulates expression of ST7 and NM23 tumor suppressor genes.

Pal S, Vishwanath SN, Erdjument-Bromage H, Tempst P, Sif S.

Mol Cell Biol. 2004 Nov;24(21):9630-45.

14.

Interaction of nucleoplasmin with core histones.

Arnan C, Saperas N, Prieto C, Chiva M, Ausió J.

J Biol Chem. 2003 Aug 15;278(33):31319-24. Epub 2003 Jun 5.

15.

Myc and Omomyc functionally associate with the Protein Arginine Methyltransferase 5 (PRMT5) in glioblastoma cells.

Mongiardi MP, Savino M, Bartoli L, Beji S, Nanni S, Scagnoli F, Falchetti ML, Favia A, Farsetti A, Levi A, Nasi S, Illi B.

Sci Rep. 2015 Nov 13;5:15494. doi: 10.1038/srep15494.

16.
17.

Blimp1 associates with Prmt5 and directs histone arginine methylation in mouse germ cells.

Ancelin K, Lange UC, Hajkova P, Schneider R, Bannister AJ, Kouzarides T, Surani MA.

Nat Cell Biol. 2006 Jun;8(6):623-30. Epub 2006 May 14.

PMID:
16699504
18.

Nucleoplasmin binds histone H2A-H2B dimers through its distal face.

Ramos I, Martín-Benito J, Finn R, Bretaña L, Aloria K, Arizmendi JM, Ausió J, Muga A, Valpuesta JM, Prado A.

J Biol Chem. 2010 Oct 29;285(44):33771-8. doi: 10.1074/jbc.M110.150664. Epub 2010 Aug 9.

19.

Association of Polycomb group SUZ12 with WD-repeat protein MEP50 that binds to histone H2A selectively in vitro.

Furuno K, Masatsugu T, Sonoda M, Sasazuki T, Yamamoto K.

Biochem Biophys Res Commun. 2006 Jul 7;345(3):1051-8. Epub 2006 May 11.

PMID:
16712789
20.

The PRMT5 arginine methyltransferase: many roles in development, cancer and beyond.

Stopa N, Krebs JE, Shechter D.

Cell Mol Life Sci. 2015 Jun;72(11):2041-59. doi: 10.1007/s00018-015-1847-9. Epub 2015 Feb 7. Review.

Supplemental Content

Support Center