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Items: 1 to 20 of 286


Telomere shortening alters the kinetics of the DNA damage response after ionizing radiation in human cells.

Drissi R, Wu J, Hu Y, Bockhold C, Dome JS.

Cancer Prev Res (Phila). 2011 Dec;4(12):1973-81. doi: 10.1158/1940-6207.CAPR-11-0069. Epub 2011 Sep 19.


Telomeres, histone code, and DNA damage response.

Misri S, Pandita S, Kumar R, Pandita TK.

Cytogenet Genome Res. 2008;122(3-4):297-307. doi: 10.1159/000167816. Epub 2009 Jan 30. Review.


No attenuation of the ATM-dependent DNA damage response in murine telomerase-deficient cells.

Erdmann N, Harrington LA.

DNA Repair (Amst). 2009 Mar 1;8(3):347-53. doi: 10.1016/j.dnarep.2008.11.009. Epub 2008 Dec 25.


Constitutive phosphorylation of ATM in lymphoblastoid cell lines from patients with ICF syndrome without downstream kinase activity.

Goldstine JV, Nahas S, Gamo K, Gartler SM, Hansen RS, Roelfsema JH, Gatti RA, Marahrens Y.

DNA Repair (Amst). 2006 Apr 8;5(4):432-43. Epub 2006 Jan 19.


DNA processing is not required for ATM-mediated telomere damage response after TRF2 deletion.

Celli GB, de Lange T.

Nat Cell Biol. 2005 Jul;7(7):712-8. Epub 2005 Jun 19.


Functional interaction of H2AX, NBS1, and p53 in ATM-dependent DNA damage responses and tumor suppression.

Kang J, Ferguson D, Song H, Bassing C, Eckersdorff M, Alt FW, Xu Y.

Mol Cell Biol. 2005 Jan;25(2):661-70.


VRK1 chromatin kinase phosphorylates H2AX and is required for foci formation induced by DNA damage.

Salzano M, Sanz-García M, Monsalve DM, Moura DS, Lazo PA.

Epigenetics. 2015;10(5):373-83. doi: 10.1080/15592294.2015.1028708. Epub 2015 Apr 29.


The HINT1 tumor suppressor regulates both gamma-H2AX and ATM in response to DNA damage.

Li H, Balajee AS, Su T, Cen B, Hei TK, Weinstein IB.

J Cell Biol. 2008 Oct 20;183(2):253-65. doi: 10.1083/jcb.200711150. Epub 2008 Oct 13.


Gamma-radiation-induced ATM-dependent signalling in human T-lymphocyte leukemic cells, MOLT-4.

Tichý A, Záskodová D, Rezácová M, Vávrová J, Vokurková D, Pejchal J, Vilasová Z, Cerman J, Osterreicher J.

Acta Biochim Pol. 2007;54(2):281-7. Epub 2007 Jun 12.


DNA-damage response and repair activities at uncapped telomeres depend on RNF8.

Peuscher MH, Jacobs JJ.

Nat Cell Biol. 2011 Aug 21;13(9):1139-45. doi: 10.1038/ncb2326.


Activation of ATM depends on chromatin interactions occurring before induction of DNA damage.

Kim YC, Gerlitz G, Furusawa T, Catez F, Nussenzweig A, Oh KS, Kraemer KH, Shiloh Y, Bustin M.

Nat Cell Biol. 2009 Jan;11(1):92-6. doi: 10.1038/ncb1817. Epub 2008 Dec 14.


Mammalian Rad9 plays a role in telomere stability, S- and G2-phase-specific cell survival, and homologous recombinational repair.

Pandita RK, Sharma GG, Laszlo A, Hopkins KM, Davey S, Chakhparonian M, Gupta A, Wellinger RJ, Zhang J, Powell SN, Roti Roti JL, Lieberman HB, Pandita TK.

Mol Cell Biol. 2006 Mar;26(5):1850-64.


Protection of telomeres through independent control of ATM and ATR by TRF2 and POT1.

Denchi EL, de Lange T.

Nature. 2007 Aug 30;448(7157):1068-71. Epub 2007 Aug 8.


Ataxia telangiectasia mutated (ATM) is dispensable for endonuclease I-SceI-induced homologous recombination in mouse embryonic stem cells.

Rass E, Chandramouly G, Zha S, Alt FW, Xie A.

J Biol Chem. 2013 Mar 8;288(10):7086-95. doi: 10.1074/jbc.M112.445825. Epub 2013 Jan 26.


Induction of MET by ionizing radiation and its role in radioresistance and invasive growth of cancer.

De Bacco F, Luraghi P, Medico E, Reato G, Girolami F, Perera T, Gabriele P, Comoglio PM, Boccaccio C.

J Natl Cancer Inst. 2011 Apr 20;103(8):645-61. doi: 10.1093/jnci/djr093. Epub 2011 Apr 4.


DNA damage recognition via activated ATM and p53 pathway in nonproliferating human prostate tissue.

Jäämaa S, Af Hällström TM, Sankila A, Rantanen V, Koistinen H, Stenman UH, Zhang Z, Yang Z, De Marzo AM, Taari K, Ruutu M, Andersson LC, Laiho M.

Cancer Res. 2010 Nov 1;70(21):8630-41. doi: 10.1158/0008-5472.CAN-10-0937. Epub 2010 Oct 26.


Telomeric protein Pin2/TRF1 as an important ATM target in response to double strand DNA breaks.

Kishi S, Zhou XZ, Ziv Y, Khoo C, Hill DE, Shiloh Y, Lu KP.

J Biol Chem. 2001 Aug 3;276(31):29282-91. Epub 2001 May 25.


Spatiotemporal characterization of ionizing radiation induced DNA damage foci and their relation to chromatin organization.

Costes SV, Chiolo I, Pluth JM, Barcellos-Hoff MH, Jakob B.

Mutat Res. 2010 Apr-Jun;704(1-3):78-87. doi: 10.1016/j.mrrev.2009.12.006. Epub 2010 Jan 8. Review.

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