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Items: 1 to 20 of 114

1.

Lethal mutagenesis of foot-and-mouth disease virus involves shifts in sequence space.

Perales C, Henry M, Domingo E, Wain-Hobson S, Vartanian JP.

J Virol. 2011 Dec;85(23):12227-40. doi: 10.1128/JVI.00716-11.

2.

Curing of foot-and-mouth disease virus from persistently infected cells by ribavirin involves enhanced mutagenesis.

Airaksinen A, Pariente N, Menéndez-Arias L, Domingo E.

Virology. 2003 Jul 5;311(2):339-49.

3.

A multi-step process of viral adaptation to a mutagenic nucleoside analogue by modulation of transition types leads to extinction-escape.

Agudo R, Ferrer-Orta C, Arias A, de la Higuera I, Perales C, Pérez-Luque R, Verdaguer N, Domingo E.

PLoS Pathog. 2010 Aug 26;6(8):e1001072. doi: 10.1371/journal.ppat.1001072.

4.

Counteracting quasispecies adaptability: extinction of a ribavirin-resistant virus mutant by an alternative mutagenic treatment.

Perales C, Agudo R, Domingo E.

PLoS One. 2009;4(5):e5554. doi: 10.1371/journal.pone.0005554.

5.

Foot-and-mouth disease virus mutant with decreased sensitivity to ribavirin: implications for error catastrophe.

Sierra M, Airaksinen A, González-López C, Agudo R, Arias A, Domingo E.

J Virol. 2007 Feb;81(4):2012-24.

6.

Influence of mutagenesis and viral load on the sustained low-level replication of an RNA virus.

Perales C, Agudo R, Manrubia SC, Domingo E.

J Mol Biol. 2011 Mar 18;407(1):60-78. doi: 10.1016/j.jmb.2011.01.026.

PMID:
21256131
7.

An antiviral mechanism investigated with ribavirin as an RNA virus mutagen for foot-and-mouth disease virus.

Gu CJ, Zheng CY, Zhang Q, Shi LL, Li Y, Qu SF.

J Biochem Mol Biol. 2006 Jan 31;39(1):9-15.

PMID:
16466632
8.

Topology of evolving, mutagenized viral populations: quasispecies expansion, compression, and operation of negative selection.

Ojosnegros S, Agudo R, Sierra M, Briones C, Sierra S, González-López C, Domingo E, Cristina J.

BMC Evol Biol. 2008 Jul 17;8:207. doi: 10.1186/1471-2148-8-207.

9.

Foot-and-mouth disease virus low-fidelity polymerase mutants are attenuated.

Xie X, Wang H, Zeng J, Li C, Zhou G, Yang D, Yu L.

Arch Virol. 2014 Oct;159(10):2641-50. doi: 10.1007/s00705-014-2126-z.

PMID:
24888311
10.

Ribavirin-resistant variants of foot-and-mouth disease virus: the effect of restricted quasispecies diversity on viral virulence.

Zeng J, Wang H, Xie X, Li C, Zhou G, Yang D, Yu L.

J Virol. 2014 Apr;88(8):4008-20. doi: 10.1128/JVI.03594-13.

11.

Foot-and-mouth disease virus evolution: exploring pathways towards virus extinction.

Domingo E, Pariente N, Airaksinen A, Gonzaĺez-Lopez C, Sierra S, Herrera M, Grande-Pérez A, Lowenstein PR, Manrubia SC, Lázaro E, Escarmís C.

Curr Top Microbiol Immunol. 2005;288:149-73. Review.

PMID:
15648178
12.

Potential benefits of sequential inhibitor-mutagen treatments of RNA virus infections.

Perales C, Agudo R, Tejero H, Manrubia SC, Domingo E.

PLoS Pathog. 2009 Nov;5(11):e1000658. doi: 10.1371/journal.ppat.1000658.

13.

Mutagenesis-mediated decrease of pathogenicity as a feature of the mutant spectrum of a viral population.

Sanz-Ramos M, Rodríguez-Calvo T, Sevilla N.

PLoS One. 2012;7(6):e39941. doi: 10.1371/journal.pone.0039941.

14.

Molecular dissection of a viral quasispecies under mutagenic treatment: positive correlation between fitness loss and mutational load.

Arias A, Isabel de Ávila A, Sanz-Ramos M, Agudo R, Escarmís C, Domingo E.

J Gen Virol. 2013 Apr;94(Pt 4):817-30. doi: 10.1099/vir.0.049171-0.

PMID:
23239576
15.

Invariant aphthovirus consensus nucleotide sequence in the transition to error catastrophe.

González-López C, Gómez-Mariano G, Escarmís C, Domingo E.

Infect Genet Evol. 2005 Oct;5(4):366-74.

PMID:
16002345
16.

Mutagenesis versus inhibition in the efficiency of extinction of foot-and-mouth disease virus.

Pariente N, Airaksinen A, Domingo E.

J Virol. 2003 Jun;77(12):7131-8.

17.

Extinction of hepatitis C virus by ribavirin in hepatoma cells involves lethal mutagenesis.

Ortega-Prieto AM, Sheldon J, Grande-Pérez A, Tejero H, Gregori J, Quer J, Esteban JI, Domingo E, Perales C.

PLoS One. 2013 Aug 16;8(8):e71039. doi: 10.1371/journal.pone.0071039.

18.

Action of mutagenic agents and antiviral inhibitors on foot-and-mouth disease virus.

Pariente N, Sierra S, Airaksinen A.

Virus Res. 2005 Feb;107(2):183-93. Review.

PMID:
15649564
19.
20.

Involvement of a joker mutation in a polymerase-independent lethal mutagenesis escape mechanism.

Agudo R, de la Higuera I, Arias A, Grande-Pérez A, Domingo E.

Virology. 2016 Jul;494:257-66. doi: 10.1016/j.virol.2016.04.023.

PMID:
27136067
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