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Menthol attenuates respiratory irritation responses to multiple cigarette smoke irritants.

Willis DN, Liu B, Ha MA, Jordt SE, Morris JB.

FASEB J. 2011 Dec;25(12):4434-44. doi: 10.1096/fj.11-188383. Epub 2011 Sep 8.


Menthol attenuates respiratory irritation and elevates blood cotinine in cigarette smoke exposed mice.

Ha MA, Smith GJ, Cichocki JA, Fan L, Liu YS, Caceres AI, Jordt SE, Morris JB.

PLoS One. 2015 Feb 13;10(2):e0117128. doi: 10.1371/journal.pone.0117128. eCollection 2015.


Menthol suppresses laryngeal C-fiber hypersensitivity to cigarette smoke in a rat model of gastroesophageal reflux disease: the role of TRPM8.

Liu BY, Lin YJ, Lee HF, Ho CY, Ruan T, Kou YR.

J Appl Physiol (1985). 2015 Mar 1;118(5):635-45. doi: 10.1152/japplphysiol.00717.2014. Epub 2014 Dec 24.


The roles of iPLA2, TRPM8 and TRPA1 in chemically induced cold hypersensitivity.

Gentry C, Stoakley N, Andersson DA, Bevan S.

Mol Pain. 2010 Jan 21;6:4. doi: 10.1186/1744-8069-6-4.


TRPM8 is the principal mediator of menthol-induced analgesia of acute and inflammatory pain.

Liu B, Fan L, Balakrishna S, Sui A, Morris JB, Jordt SE.

Pain. 2013 Oct;154(10):2169-77. doi: 10.1016/j.pain.2013.06.043. Epub 2013 Jun 29.


Menthol decreases oral nicotine aversion in C57BL/6 mice through a TRPM8-dependent mechanism.

Fan L, Balakrishna S, Jabba SV, Bonner PE, Taylor SR, Picciotto MR, Jordt SE.

Tob Control. 2016 Nov;25(Suppl 2):ii50-ii54. doi: 10.1136/tobaccocontrol-2016-053209. Epub 2016 Oct 3.


Bimodal action of menthol on the transient receptor potential channel TRPA1.

Karashima Y, Damann N, Prenen J, Talavera K, Segal A, Voets T, Nilius B.

J Neurosci. 2007 Sep 12;27(37):9874-84.


TRPM8 ion channel ligands for new therapeutic applications and as probes to study menthol pharmacology.

Journigan VB, Zaveri NT.

Life Sci. 2013 Mar 19;92(8-9):425-37. doi: 10.1016/j.lfs.2012.10.032. Epub 2012 Nov 16. Review.


Involvement of cholinergic nicotinic receptors in the menthol-induced gastric relaxation.

Amato A, Serio R, Mulè F.

Eur J Pharmacol. 2014 Dec 15;745:129-34. doi: 10.1016/j.ejphar.2014.10.012. Epub 2014 Oct 16.


Perception of specific trigeminal chemosensory agonists.

Frasnelli J, Albrecht J, Bryant B, Lundström JN.

Neuroscience. 2011 Aug 25;189:377-83. doi: 10.1016/j.neuroscience.2011.04.065. Epub 2011 May 7.


Activation of the cold-receptor TRPM8 by low levels of menthol in tobacco products.

Paschke M, Tkachenko A, Ackermann K, Hutzler C, Henkler F, Luch A.

Toxicol Lett. 2017 Apr 5;271:50-57. doi: 10.1016/j.toxlet.2017.02.020. Epub 2017 Feb 24.


Menthol--pharmacology of an important naturally medicinal "cool".

Farco JA, Grundmann O.

Mini Rev Med Chem. 2013 Jan;13(1):124-31. Review.


Emergence of functional sensory subtypes as defined by transient receptor potential channel expression.

Hjerling-Leffler J, Alqatari M, Ernfors P, Koltzenburg M.

J Neurosci. 2007 Mar 7;27(10):2435-43.


1,8-cineole, a TRPM8 agonist, is a novel natural antagonist of human TRPA1.

Takaishi M, Fujita F, Uchida K, Yamamoto S, Sawada Shimizu M, Hatai Uotsu C, Shimizu M, Tominaga M.

Mol Pain. 2012 Nov 29;8:86. doi: 10.1186/1744-8069-8-86.


Cigarette smoke-induced neurogenic inflammation is mediated by alpha,beta-unsaturated aldehydes and the TRPA1 receptor in rodents.

Andrè E, Campi B, Materazzi S, Trevisani M, Amadesi S, Massi D, Creminon C, Vaksman N, Nassini R, Civelli M, Baraldi PG, Poole DP, Bunnett NW, Geppetti P, Patacchini R.

J Clin Invest. 2008 Jul;118(7):2574-82. doi: 10.1172/JCI34886.


Cigarette smoke has sensory effects through nicotinic and TRPA1 but not TRPV1 receptors on the isolated mouse trachea and larynx.

Kichko TI, Kobal G, Reeh PW.

Am J Physiol Lung Cell Mol Physiol. 2015 Oct 15;309(8):L812-20. doi: 10.1152/ajplung.00164.2015. Epub 2015 Aug 21.


Activation of transient receptor potential ankyrin-1 (TRPA1) in lung cells by wood smoke particulate material.

Shapiro D, Deering-Rice CE, Romero EG, Hughen RW, Light AR, Veranth JM, Reilly CA.

Chem Res Toxicol. 2013 May 20;26(5):750-8. doi: 10.1021/tx400024h. Epub 2013 Apr 25.


Reciprocal effects of capsaicin and menthol on thermosensation through regulated activities of TRPV1 and TRPM8.

Takaishi M, Uchida K, Suzuki Y, Matsui H, Shimada T, Fujita F, Tominaga M.

J Physiol Sci. 2016 Mar;66(2):143-55. doi: 10.1007/s12576-015-0427-y. Epub 2015 Dec 8.


Transient receptor potential channels in sensory neurons are targets of the antimycotic agent clotrimazole.

Meseguer V, Karashima Y, Talavera K, D'Hoedt D, Donovan-Rodríguez T, Viana F, Nilius B, Voets T.

J Neurosci. 2008 Jan 16;28(3):576-86. doi: 10.1523/JNEUROSCI.4772-07.2008.

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