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Items: 1 to 20 of 93

1.

Efficient synthesis of apricoxib, CS-706, a selective cyclooxygenase-2 inhibitor, and evaluation of inhibition of prostaglandin E2 production in inflammatory breast cancer cells.

Mandal PK, Freiter EM, Bagsby AL, Robertson FM, McMurray JS.

Bioorg Med Chem Lett. 2011 Oct 15;21(20):6071-3. doi: 10.1016/j.bmcl.2011.08.050. Epub 2011 Aug 19.

2.

Apricoxib upregulates 15-PGDH and PGT in tobacco-related epithelial malignancies.

St John MA, Wang G, Luo J, Dohadwala M, Hu D, Lin Y, Dennis M, Lee JM, Elashoff D, Lawhon T, Zaknoen SL, Burrows FJ, Dubinett SM.

Br J Cancer. 2012 Aug 7;107(4):707-12. doi: 10.1038/bjc.2012.203. Epub 2012 Jul 24.

3.

Epithelial-mesenchymal transition increases tumor sensitivity to COX-2 inhibition by apricoxib.

Kirane A, Toombs JE, Larsen JE, Ostapoff KT, Meshaw KR, Zaknoen S, Brekken RA, Burrows FJ.

Carcinogenesis. 2012 Sep;33(9):1639-46. doi: 10.1093/carcin/bgs195. Epub 2012 Jun 7.

4.

Apricoxib, a COX-2 inhibitor for the potential treatment of pain and cancer.

Rao PN, Grover RK.

IDrugs. 2009 Nov;12(11):711-22.

PMID:
19844858
5.

Apricoxib, a novel inhibitor of COX-2, markedly improves standard therapy response in molecularly defined models of pancreatic cancer.

Kirane A, Toombs JE, Ostapoff K, Carbon JG, Zaknoen S, Braunfeld J, Schwarz RE, Burrows FJ, Brekken RA.

Clin Cancer Res. 2012 Sep 15;18(18):5031-42. doi: 10.1158/1078-0432.CCR-12-0453. Epub 2012 Jul 24.

6.

Direct evidence for a role of cyclooxygenase 2-derived prostaglandin E2 in human head and neck xenograft tumors.

Zweifel BS, Davis TW, Ornberg RL, Masferrer JL.

Cancer Res. 2002 Nov 15;62(22):6706-11.

7.

Inhibition of cyclooxygenase-2 activity by celecoxib does not lead to radiosensitization of human prostate cancer cells in vitro.

Ohneseit PA, Krebiehl G, Dittmann K, Kehlbach R, Rodemann HP.

Radiother Oncol. 2007 Feb;82(2):229-38. Epub 2007 Jan 4.

PMID:
17207548
8.

Synthesis and evaluation of the anti-inflammatory properties of selenium-derivatives of celecoxib.

Desai D, Kaushal N, Gandhi UH, Arner RJ, D'Souza C, Chen G, Vunta H, El-Bayoumy K, Amin S, Prabhu KS.

Chem Biol Interact. 2010 Dec 5;188(3):446-56. doi: 10.1016/j.cbi.2010.09.021. Epub 2010 Sep 29.

9.

Selective COX-2 inhibitors. Part 1: synthesis and biological evaluation of phenylazobenzenesulfonamides.

Tsai WJ, Shiao YJ, Lin SJ, Chiou WF, Lin LC, Yang TH, Teng CM, Wu TS, Yang LM.

Bioorg Med Chem Lett. 2006 Sep 1;16(17):4440-3. Epub 2006 Jun 30.

PMID:
16814546
10.
11.

Inhibition of prostaglandin E2 production by synthetic wogonin analogs.

Gurung SK, Kim HP, Park H.

Arch Pharm Res. 2009 Nov;32(11):1503-8. doi: 10.1007/s12272-009-2101-5.

PMID:
20091262
12.

Synthesis and release of human cartilage matrix proteoglycans are differently regulated by nitric oxide and prostaglandin-E2.

Mastbergen SC, Bijlsma JW, Lafeber FP.

Ann Rheum Dis. 2008 Jan;67(1):52-8. Epub 2007 May 7.

PMID:
17485421
13.

Adenovirus type 5 E1A-induced apoptosis in COX-2-overexpressing breast cancer cells.

Sugimoto T, Bartholomeusz C, Tari AM, Ueno NT.

Breast Cancer Res. 2007;9(4):R41.

14.

Inhibition of cyclooxygenase-2, but not cyclooxygenase-1, reduces prostaglandin E2 secretion from diabetic rat retinas.

Ayalasomayajula SP, Amrite AC, Kompella UB.

Eur J Pharmacol. 2004 Sep 13;498(1-3):275-8.

PMID:
15364005
15.

Selective COX-2 inhibitors. Part 2: synthesis and biological evaluation of 4-benzylideneamino- and 4-phenyliminomethyl-benzenesulfonamides.

Lin SJ, Tsai WJ, Chiou WF, Yang TH, Yang LM.

Bioorg Med Chem. 2008 Mar 1;16(5):2697-706. Epub 2007 Nov 17.

PMID:
18063374
17.

The anti-inflammatory effect of cyclooxygenase inhibitors in fibroblast-like synoviocytes from the human temporomandibular joint results from the suppression of PGE2 production.

Kawashima M, Ogura N, Akutsu M, Ito K, Kondoh T.

J Oral Pathol Med. 2013 Jul;42(6):499-506. doi: 10.1111/jop.12045. Epub 2013 Jan 18.

18.

1,2-Diarylpyrroles as potent and selective inhibitors of cyclooxygenase-2.

Khanna IK, Weier RM, Yu Y, Collins PW, Miyashiro JM, Koboldt CM, Veenhuizen AW, Currie JL, Seibert K, Isakson PC.

J Med Chem. 1997 May 23;40(11):1619-33.

PMID:
9171872
19.

Antitumor effects of inhibitors of nitric oxide synthase or cyclooxygenase-2 on human KB carcinoma cells overexpressing COX-2.

Ohtsu N, Takaoka K, Segawa E, Hashitani S, Noguchi K, Kishimoto H, Urade M.

Oncol Rep. 2010 Jul;24(1):31-6.

PMID:
20514441
20.

A novel role for cyclooxygenase-2 in regulating vascular channel formation by human breast cancer cells.

Basu GD, Liang WS, Stephan DA, Wegener LT, Conley CR, Pockaj BA, Mukherjee P.

Breast Cancer Res. 2006;8(6):R69.

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