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Items: 1 to 20 of 113

1.

CD4⁺CD25⁺Foxp3⁺ regulatory T cell formation requires more specific recognition of a self-peptide than thymocyte deletion.

Cozzo Picca C, Simons DM, Oh S, Aitken M, Perng OA, Mergenthaler C, Kropf E, Erikson J, Caton AJ.

Proc Natl Acad Sci U S A. 2011 Sep 6;108(36):14890-5. doi: 10.1073/pnas.1103810108. Epub 2011 Aug 22.

2.

Strength of TCR signal from self-peptide modulates autoreactive thymocyte deletion and Foxp3(+) Treg-cell formation.

Caton AJ, Kropf E, Simons DM, Aitken M, Weissler KA, Jordan MS.

Eur J Immunol. 2014 Mar;44(3):785-93. doi: 10.1002/eji.201343767. Epub 2013 Dec 27.

3.

Thymocyte deletion can bias Treg formation toward low-abundance self-peptide.

Picca CC, Oh S, Panarey L, Aitken M, Basehoar A, Caton AJ.

Eur J Immunol. 2009 Dec;39(12):3301-6. doi: 10.1002/eji.200939709.

4.
5.

CD4+CD25+ regulatory T cell repertoire formation shaped by differential presentation of peptides from a self-antigen.

Larkin J 3rd, Rankin AL, Picca CC, Riley MP, Jenks SA, Sant AJ, Caton AJ.

J Immunol. 2008 Feb 15;180(4):2149-57.

6.

Shaping of the autoreactive regulatory T cell repertoire by thymic cortical positive selection.

Ribot J, Enault G, Pilipenko S, Huchenq A, Calise M, Hudrisier D, Romagnoli P, van Meerwijk JP.

J Immunol. 2007 Nov 15;179(10):6741-8.

7.

Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide.

Jordan MS, Boesteanu A, Reed AJ, Petrone AL, Holenbeck AE, Lerman MA, Naji A, Caton AJ.

Nat Immunol. 2001 Apr;2(4):301-6.

PMID:
11276200
8.

Role of TCR specificity in CD4+ CD25+ regulatory T-cell selection.

Picca CC, Larkin J 3rd, Boesteanu A, Lerman MA, Rankin AL, Caton AJ.

Immunol Rev. 2006 Aug;212:74-85. Review.

PMID:
16903907
9.

CD4+ T-cell development in a mouse expressing a transgenic TCR derived from a Treg.

DiPaolo RJ, Shevach EM.

Eur J Immunol. 2009 Jan;39(1):234-40. doi: 10.1002/eji.200838772.

10.

Regulatory T-cell differentiation versus clonal deletion of autoreactive thymocytes.

Wirnsberger G, Hinterberger M, Klein L.

Immunol Cell Biol. 2011 Jan;89(1):45-53. doi: 10.1038/icb.2010.123. Epub 2010 Nov 2. Review.

PMID:
21042335
12.

Regulatory T cells: roles of T cell receptor for their development and function.

Ohkura N, Sakaguchi S.

Semin Immunopathol. 2010 Jun;32(2):95-106. doi: 10.1007/s00281-010-0200-5. Epub 2010 Feb 24. Review.

PMID:
20179931
13.

Activation of CD4+ CD25+ regulatory T cell suppressor function by analogs of the selecting peptide.

Larkin J 3rd, Picca CC, Caton AJ.

Eur J Immunol. 2007 Jan;37(1):139-46.

14.
15.

CD4(+) CD25(+) regulatory T cell selection.

Caton AJ, Cozzo C, Larkin J 3rd, Lerman MA, Boesteanu A, Jordan MS.

Ann N Y Acad Sci. 2004 Dec;1029:101-14. Review.

PMID:
15681750
16.

Thymus and autoimmunity: production of CD25+CD4+ naturally anergic and suppressive T cells as a key function of the thymus in maintaining immunologic self-tolerance.

Itoh M, Takahashi T, Sakaguchi N, Kuniyasu Y, Shimizu J, Otsuka F, Sakaguchi S.

J Immunol. 1999 May 1;162(9):5317-26.

17.

A signal integration model of thymic selection and natural regulatory T cell commitment.

Khailaie S, Robert PA, Toker A, Huehn J, Meyer-Hermann M.

J Immunol. 2014 Dec 15;193(12):5983-96. doi: 10.4049/jimmunol.1400889. Epub 2014 Nov 12.

18.

A role for accessibility to self-peptide-self-MHC complexes in intrathymic negative selection.

Viret C, Sant'Angelo DB, He X, Ramaswamy H, Janeway CA Jr.

J Immunol. 2001 Apr 1;166(7):4429-37.

19.
20.

Distinct modes of antigen presentation promote the formation, differentiation, and activity of foxp3+ regulatory T cells in vivo.

Weissler KA, Garcia V, Kropf E, Aitken M, Bedoya F, Wolf AI, Erikson J, Caton AJ.

J Immunol. 2015 Apr 15;194(8):3784-97. doi: 10.4049/jimmunol.1402960. Epub 2015 Mar 16.

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