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Notch pathway activation can replace the requirement for Wnt4 and Wnt9b in mesenchymal-to-epithelial transition of nephron stem cells.

Boyle SC, Kim M, Valerius MT, McMahon AP, Kopan R.

Development. 2011 Oct;138(19):4245-54. doi: 10.1242/dev.070433. Epub 2011 Aug 18.


Wnt4 induces nephronic tubules in metanephric mesenchyme by a non-canonical mechanism.

Tanigawa S, Wang H, Yang Y, Sharma N, Tarasova N, Ajima R, Yamaguchi TP, Rodriguez LG, Perantoni AO.

Dev Biol. 2011 Apr 1;352(1):58-69. doi: 10.1016/j.ydbio.2011.01.012. Epub 2011 Jan 21.


Wnt/beta-catenin signaling regulates nephron induction during mouse kidney development.

Park JS, Valerius MT, McMahon AP.

Development. 2007 Jul;134(13):2533-9. Epub 2007 May 30.


Notch is required for the formation of all nephron segments and primes nephron progenitors for differentiation.

Chung E, Deacon P, Park JS.

Development. 2017 Dec 15;144(24):4530-4539. doi: 10.1242/dev.156661. Epub 2017 Nov 7.


Zebrafish nephrogenesis is regulated by interactions between retinoic acid, mecom, and Notch signaling.

Li Y, Cheng CN, Verdun VA, Wingert RA.

Dev Biol. 2014 Feb 1;386(1):111-22. doi: 10.1016/j.ydbio.2013.11.021. Epub 2013 Dec 3.


Epithelial cell fate in the nephron tubule is mediated by the ETS transcription factors etv5a and etv4 during zebrafish kidney development.

Marra AN, Wingert RA.

Dev Biol. 2016 Mar 15;411(2):231-245. doi: 10.1016/j.ydbio.2016.01.035. Epub 2016 Jan 29.


WNT/beta-catenin signaling in nephron progenitors and their epithelial progeny.

Schmidt-Ott KM, Barasch J.

Kidney Int. 2008 Oct;74(8):1004-8. doi: 10.1038/ki.2008.322. Epub 2008 Jul 16. Review.


Induction and patterning of the metanephric nephron.

O'Brien LL, McMahon AP.

Semin Cell Dev Biol. 2014 Dec;36:31-8. doi: 10.1016/j.semcdb.2014.08.014. Epub 2014 Sep 3. Review.


Notch2 activation in the embryonic kidney depletes nephron progenitors.

Fujimura S, Jiang Q, Kobayashi C, Nishinakamura R.

J Am Soc Nephrol. 2010 May;21(5):803-10. doi: 10.1681/ASN.2009040353. Epub 2010 Mar 18.


Canonical Wnt9b signaling balances progenitor cell expansion and differentiation during kidney development.

Karner CM, Das A, Ma Z, Self M, Chen C, Lum L, Oliver G, Carroll TJ.

Development. 2011 Apr;138(7):1247-57. doi: 10.1242/dev.057646. Epub 2011 Feb 24.


Conditional expression of Wnt9b in Six2-positive cells disrupts stomach and kidney function.

Kiefer SM, Robbins L, Rauchman M.

PLoS One. 2012;7(8):e43098. doi: 10.1371/journal.pone.0043098. Epub 2012 Aug 17.


Wnt and Notch pathways have interrelated opposing roles on prostate progenitor cell proliferation and differentiation.

Shahi P, Seethammagari MR, Valdez JM, Xin L, Spencer DM.

Stem Cells. 2011 Apr;29(4):678-88. doi: 10.1002/stem.606.


Regulation of intestinal stem cells by Wnt and Notch signalling.

Horvay K, Abud HE.

Adv Exp Med Biol. 2013;786:175-86. doi: 10.1007/978-94-007-6621-1_10.


Nephron progenitors in the metanephric mesenchyme.

Nishinakamura R, Uchiyama Y, Sakaguchi M, Fujimura S.

Pediatr Nephrol. 2011 Sep;26(9):1463-7. doi: 10.1007/s00467-011-1806-0. Epub 2011 Feb 19. Review.


Secreted Frizzled-related proteins can regulate metanephric development.

Yoshino K, Rubin JS, Higinbotham KG, Uren A, Anest V, Plisov SY, Perantoni AO.

Mech Dev. 2001 Apr;102(1-2):45-55.


Mapping of the fate of cell lineages generated from cells that express the Wnt4 gene by time-lapse during kidney development.

Shan J, Jokela T, Skovorodkin I, Vainio S.

Differentiation. 2010 Jan;79(1):57-64. doi: 10.1016/j.diff.2009.08.006. Epub 2009 Sep 9.


Dissecting stages of mesenchymal-to-epithelial conversion during kidney development.

Schmidt-Ott KM, Lan D, Hirsh BJ, Barasch J.

Nephron Physiol. 2006;104(1):p56-60. Epub 2006 May 24. Review.


Lineage enforcement by inductive mesenchyme on adult epithelial stem cells across developmental germ layers.

Taylor RA, Wang H, Wilkinson SE, Richards MG, Britt KL, Vaillant F, Lindeman GJ, Visvader JE, Cunha GR, St John J, Risbridger GP.

Stem Cells. 2009 Dec;27(12):3032-42. doi: 10.1002/stem.244.


Notch activates Wnt-4 signalling to control medio-lateral patterning of the pronephros.

Naylor RW, Jones EA.

Development. 2009 Nov;136(21):3585-95. doi: 10.1242/dev.042606. Epub 2009 Sep 30.


Pygopus 2: tilting the Wnt-Notch balance in mammary epithelial lineage determination.

Roarty K, Rosen JM.

Breast Cancer Res. 2013 Dec 23;15(6):322. doi: 10.1186/bcr3592.

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