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Items: 1 to 20 of 130

1.

Specific detection of OCT3/4 isoform A/B/B1 expression in solid (germ cell) tumours and cell lines: confirmation of OCT3/4 specificity for germ cell tumours.

Rijlaarsdam MA, van Herk HA, Gillis AJ, Stoop H, Jenster G, Martens J, van Leenders GJ, Dinjens W, Hoogland AM, Timmermans M, Looijenga LH.

Br J Cancer. 2011 Sep 6;105(6):854-63. doi: 10.1038/bjc.2011.270. Epub 2011 Aug 16. Erratum in: Br J Cancer. 2012 Feb 14;106(4):791.

2.

POU5F1 (OCT3/4) identifies cells with pluripotent potential in human germ cell tumors.

Looijenga LH, Stoop H, de Leeuw HP, de Gouveia Brazao CA, Gillis AJ, van Roozendaal KE, van Zoelen EJ, Weber RF, Wolffenbuttel KP, van Dekken H, Honecker F, Bokemeyer C, Perlman EJ, Schneider DT, Kononen J, Sauter G, Oosterhuis JW.

Cancer Res. 2003 May 1;63(9):2244-50.

3.

Expression and interdependencies of pluripotency factors LIN28, OCT3/4, NANOG and SOX2 in human testicular germ cells and tumours of the testis.

Gillis AJ, Stoop H, Biermann K, van Gurp RJ, Swartzman E, Cribbes S, Ferlinz A, Shannon M, Oosterhuis JW, Looijenga LH.

Int J Androl. 2011 Aug;34(4 Pt 2):e160-74. doi: 10.1111/j.1365-2605.2011.01148.x. Epub 2011 Jun 2.

PMID:
21631526
4.

OCT4: biological functions and clinical applications as a marker of germ cell neoplasia.

Cheng L, Sung MT, Cossu-Rocca P, Jones TD, MacLennan GT, De Jong J, Lopez-Beltran A, Montironi R, Looijenga LH.

J Pathol. 2007 Jan;211(1):1-9. Review.

PMID:
17117392
5.

Embryonic stem cell transcription factor signatures in the diagnosis of primary and metastatic germ cell tumors.

Santagata S, Ligon KL, Hornick JL.

Am J Surg Pathol. 2007 Jun;31(6):836-45.

PMID:
17527070
6.

Differential methylation of the OCT3/4 upstream region in primary human testicular germ cell tumors.

De Jong J, Weeda S, Gillis AJ, Oosterhuis JW, Looijenga LH.

Oncol Rep. 2007 Jul;18(1):127-32.

PMID:
17549357
7.

MAGEC2 is a sensitive and novel marker for seminoma: a tissue microarray analysis of 325 testicular germ cell tumors.

Bode PK, Barghorn A, Fritzsche FR, Riener MO, Kristiansen G, Knuth A, Moch H.

Mod Pathol. 2011 Jun;24(6):829-35.

PMID:
21780320
8.

Testicular mixed germ cell tumors: a morphological and immunohistochemical study using stem cell markers, OCT3/4, SOX2 and GDF3, with emphasis on morphologically difficult-to-classify areas.

Gopalan A, Dhall D, Olgac S, Fine SW, Korkola JE, Houldsworth J, Chaganti RS, Bosl GJ, Reuter VE, Tickoo SK.

Mod Pathol. 2009 Aug;22(8):1066-74. doi: 10.1038/modpathol.2009.66. Epub 2009 Apr 24.

9.

Human testicular (non)seminomatous germ cell tumours: the clinical implications of recent pathobiological insights.

Looijenga LH.

J Pathol. 2009 Jun;218(2):146-62. doi: 10.1002/path.2522. Review.

PMID:
19253916
10.

The novel function of OCT4B isoform-265 in genotoxic stress.

Gao Y, Wei J, Han J, Wang X, Su G, Zhao Y, Chen B, Xiao Z, Cao J, Dai J.

Stem Cells. 2012 Apr;30(4):665-72. doi: 10.1002/stem.1034.

11.

[OCT4 expression in hepatocellular carcinoma and its clinical significance].

Huang PZ, Lu CL, Li BK, Hong J, Huang L, Wang L, Zhang Y, Yuan YF.

Chin J Cancer. 2010 Jan;29(1):111-16. Chinese.

12.

OCT4 staining in testicular tumors: a sensitive and specific marker for seminoma and embryonal carcinoma.

Jones TD, Ulbright TM, Eble JN, Baldridge LA, Cheng L.

Am J Surg Pathol. 2004 Jul;28(7):935-40.

PMID:
15223965
13.

Expression of embryonic stem cell markers in cultured JKT-1, a cell line derived from a human seminoma.

Bouskine A, Vega A, Nebout M, Benahmed M, FĂ©nichel P.

Int J Androl. 2010 Feb;33(1):54-63. doi: 10.1111/j.1365-2605.2009.00950.x. Epub 2009 Feb 10.

PMID:
19226408
14.

Stem cell marker OCT3/4 in tumor biology and germ cell tumor diagnostics: history and future.

de Jong J, Looijenga LH.

Crit Rev Oncog. 2006 Dec;12(3-4):171-203. Review.

PMID:
17425502
15.

Oct3/4 and Sox2 are significantly associated with an unfavorable clinical outcome in human esophageal squamous cell carcinoma.

Wang Q, He W, Lu C, Wang Z, Wang J, Giercksky KE, Nesland JM, Suo Z.

Anticancer Res. 2009 Apr;29(4):1233-41.

16.

Global DNA methylation in fetal human germ cells and germ cell tumours: association with differentiation and cisplatin resistance.

Wermann H, Stoop H, Gillis AJ, Honecker F, van Gurp RJ, Ammerpohl O, Richter J, Oosterhuis JW, Bokemeyer C, Looijenga LH.

J Pathol. 2010 Aug;221(4):433-42. doi: 10.1002/path.2725.

PMID:
20593487
17.

Role of SOX2 in the etiology of embryonal carcinoma, based on analysis of the NCCIT and NT2 cell lines.

Eini R, Stoop H, Gillis AJ, Biermann K, Dorssers LC, Looijenga LH.

PLoS One. 2014 Jan 3;9(1):e83585. doi: 10.1371/journal.pone.0083585. eCollection 2014.

18.

The novel OCT4 spliced variant OCT4B1 can generate three protein isoforms by alternative splicing into OCT4B.

Gao Y, Wang X, Han J, Xiao Z, Chen B, Su G, Dai J.

J Genet Genomics. 2010 Jul;37(7):461-5. doi: 10.1016/S1673-8527(09)60065-5.

PMID:
20659710
19.

Diagnostic value of OCT3/4 for pre-invasive and invasive testicular germ cell tumours.

de Jong J, Stoop H, Dohle GR, Bangma CH, Kliffen M, van Esser JW, van den Bent M, Kros JM, Oosterhuis JW, Looijenga LH.

J Pathol. 2005 Jun;206(2):242-9.

PMID:
15818593
20.

OCT4B modulates OCT4A expression as ceRNA in tumor cells.

Li D, Yang ZK, Bu JY, Xu CY, Sun H, Tang JB, Lin P, Cheng W, Huang N, Cui RJ, Yu XG, Zheng XL.

Oncol Rep. 2015 May;33(5):2622-30. doi: 10.3892/or.2015.3862. Epub 2015 Mar 18.

PMID:
25812694

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