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Items: 1 to 20 of 129

1.

Enhancement of proteasomal function protects against cardiac proteinopathy and ischemia/reperfusion injury in mice.

Li J, Horak KM, Su H, Sanbe A, Robbins J, Wang X.

J Clin Invest. 2011 Sep;121(9):3689-700. doi: 10.1172/JCI45709. Epub 2011 Aug 15.

2.

Genetically induced moderate inhibition of the proteasome in cardiomyocytes exacerbates myocardial ischemia-reperfusion injury in mice.

Tian Z, Zheng H, Li J, Li Y, Su H, Wang X.

Circ Res. 2012 Aug 17;111(5):532-42. doi: 10.1161/CIRCRESAHA.112.270983. Epub 2012 Jun 26.

3.

Enhancement of proteasome function by PA28α overexpression protects against oxidative stress.

Li J, Powell SR, Wang X.

FASEB J. 2011 Mar;25(3):883-93. doi: 10.1096/fj.10-160895. Epub 2010 Nov 23.

4.

Protein kinase g positively regulates proteasome-mediated degradation of misfolded proteins.

Ranek MJ, Terpstra EJ, Li J, Kass DA, Wang X.

Circulation. 2013 Jul 23;128(4):365-76. doi: 10.1161/CIRCULATIONAHA.113.001971. Epub 2013 Jun 14.

5.

COP9 signalosome controls the degradation of cytosolic misfolded proteins and protects against cardiac proteotoxicity.

Su H, Li J, Zhang H, Ma W, Wei N, Liu J, Wang X.

Circ Res. 2015 Nov 6;117(11):956-66. doi: 10.1161/CIRCRESAHA.115.306783. Epub 2015 Sep 17.

6.

Cardiac proteasome functional insufficiency plays a pathogenic role in diabetic cardiomyopathy.

Li J, Ma W, Yue G, Tang Y, Kim IM, Weintraub NL, Wang X, Su H.

J Mol Cell Cardiol. 2017 Jan;102:53-60. doi: 10.1016/j.yjmcc.2016.11.013. Epub 2016 Nov 30.

PMID:
27913284
7.

Activation of PKN mediates survival of cardiac myocytes in the heart during ischemia/reperfusion.

Takagi H, Hsu CP, Kajimoto K, Shao D, Yang Y, Maejima Y, Zhai P, Yehia G, Yamada C, Zablocki D, Sadoshima J.

Circ Res. 2010 Sep 3;107(5):642-9. doi: 10.1161/CIRCRESAHA.110.217554. Epub 2010 Jul 1.

8.

Sumo E2 enzyme UBC9 is required for efficient protein quality control in cardiomyocytes.

Gupta MK, Gulick J, Liu R, Wang X, Molkentin JD, Robbins J.

Circ Res. 2014 Sep 26;115(8):721-9. doi: 10.1161/CIRCRESAHA.115.304760. Epub 2014 Aug 5.

9.
10.

The ubiquitin-proteasome system in cardiac proteinopathy: a quality control perspective.

Su H, Wang X.

Cardiovasc Res. 2010 Jan 15;85(2):253-62. doi: 10.1093/cvr/cvp287. Epub 2009 Aug 20. Review.

11.

Perturbation of cullin deneddylation via conditional Csn8 ablation impairs the ubiquitin-proteasome system and causes cardiomyocyte necrosis and dilated cardiomyopathy in mice.

Su H, Li J, Menon S, Liu J, Kumarapeli AR, Wei N, Wang X.

Circ Res. 2011 Jan 7;108(1):40-50. doi: 10.1161/CIRCRESAHA.110.230607. Epub 2010 Nov 4.

12.

Autophagy and p62 in cardiac proteinopathy.

Zheng Q, Su H, Ranek MJ, Wang X.

Circ Res. 2011 Jul 22;109(3):296-308. doi: 10.1161/CIRCRESAHA.111.244707. Epub 2011 Jun 9.

13.

Proteasome functional insufficiency in cardiac pathogenesis.

Wang X, Li J, Zheng H, Su H, Powell SR.

Am J Physiol Heart Circ Physiol. 2011 Dec;301(6):H2207-19. doi: 10.1152/ajpheart.00714.2011. Epub 2011 Sep 23. Review.

14.

Impairment of the ubiquitin-proteasome system in desminopathy mouse hearts.

Liu J, Chen Q, Huang W, Horak KM, Zheng H, Mestril R, Wang X.

FASEB J. 2006 Feb;20(2):362-4. Epub 2005 Dec 21.

PMID:
16371426
15.

Search and destroy: the role of protein quality control in maintaining cardiac function.

Patterson C.

J Mol Cell Cardiol. 2006 Apr;40(4):438-41. Epub 2006 Mar 6. No abstract available.

PMID:
16516914
16.

The ubiquitin-proteasome system: focus on the heart.

Zolk O, Schenke C, Sarikas A.

Cardiovasc Res. 2006 Jun 1;70(3):410-21. Epub 2006 Feb 23. Review.

PMID:
16497285
17.

Doxycycline attenuates protein aggregation in cardiomyocytes and improves survival of a mouse model of cardiac proteinopathy.

Zheng H, Tang M, Zheng Q, Kumarapeli AR, Horak KM, Tian Z, Wang X.

J Am Coll Cardiol. 2010 Oct 19;56(17):1418-26. doi: 10.1016/j.jacc.2010.01.075.

18.

The ubiquitin ligase MuRF1 protects against cardiac ischemia/reperfusion injury by its proteasome-dependent degradation of phospho-c-Jun.

Li HH, Du J, Fan YN, Zhang ML, Liu DP, Li L, Lockyer P, Kang EY, Patterson C, Willis MS.

Am J Pathol. 2011 Mar;178(3):1043-58. doi: 10.1016/j.ajpath.2010.11.049.

19.

Overexpression of histidine-rich Ca-binding protein protects against ischemia/reperfusion-induced cardiac injury.

Zhou X, Fan GC, Ren X, Waggoner JR, Gregory KN, Chen G, Jones WK, Kranias EG.

Cardiovasc Res. 2007 Aug 1;75(3):487-97. Epub 2007 Apr 19.

PMID:
17499229
20.

Priming the proteasome by protein kinase G: a novel cardioprotective mechanism of sildenafil.

Zhang H, Wang X.

Future Cardiol. 2015 Mar;11(2):177-89. doi: 10.2217/fca.15.3. Review.

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