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Items: 1 to 20 of 117


Quantitative analysis of protein phosphorylations and interactions by multi-colour IP-FCM as an input for kinetic modelling of signalling networks.

Deswal S, Schulze AK, Höfer T, Schamel WW.

PLoS One. 2011;6(7):e22928. doi: 10.1371/journal.pone.0022928. Epub 2011 Jul 29.


Intracellular Phospho-Flow cytometry reveals novel insights into TCR proximal signaling events. A comparison with Western blot.

Haas A, Weckbecker G, Welzenbach K.

Cytometry A. 2008 Sep;73(9):799-807. doi: 10.1002/cyto.a.20598.


Docking protein Gab2 is phosphorylated by ZAP-70 and negatively regulates T cell receptor signaling by recruitment of inhibitory molecules.

Yamasaki S, Nishida K, Hibi M, Sakuma M, Shiina R, Takeuchi A, Ohnishi H, Hirano T, Saito T.

J Biol Chem. 2001 Nov 30;276(48):45175-83. Epub 2001 Sep 25.


Contributions of the T cell receptor-associated CD3gamma-ITAM to thymocyte selection.

Haks MC, Pépin E, van den Brakel JH, Smeele SA, Belkowski SM, Kessels HW, Krimpenfort P, Kruisbeek AM.

J Exp Med. 2002 Jul 1;196(1):1-13.


Prolonged exposure of T cells to TNF down-regulates TCR zeta and expression of the TCR/CD3 complex at the cell surface.

Isomäki P, Panesar M, Annenkov A, Clark JM, Foxwell BM, Chernajovsky Y, Cope AP.

J Immunol. 2001 May 1;166(9):5495-507.


Fine-tuning of proximal TCR signaling by ZAP-70 tyrosine residues in Jurkat cells.

Szabo M, Czompoly T, Kvell K, Talaber G, Bartis D, Nemeth P, Berki T, Boldizsar F.

Int Immunol. 2012 Feb;24(2):79-87. doi: 10.1093/intimm/dxr105. Epub 2011 Dec 29.


IP-FCM measures physiologic protein-protein interactions modulated by signal transduction and small-molecule drug inhibition.

Smith SE, Bida AT, Davis TR, Sicotte H, Patterson SE, Gil D, Schrum AG.

PLoS One. 2012;7(9):e45722. doi: 10.1371/journal.pone.0045722. Epub 2012 Sep 21.


Dynamics of proximal signaling events after TCR/CD8-mediated induction of proliferation or apoptosis in mature CD8+ T cells.

Wang X, Simeoni L, Lindquist JA, Saez-Rodriguez J, Ambach A, Gilles ED, Kliche S, Schraven B.

J Immunol. 2008 May 15;180(10):6703-12.


Regulation of TCR signal transduction in murine thymocytes by multiple TCR zeta-chain signaling motifs.

van Oers NS, Love PE, Shores EW, Weiss A.

J Immunol. 1998 Jan 1;160(1):163-70.


Involvement of hematopoietic progenitor kinase 1 in T cell receptor signaling.

Ling P, Meyer CF, Redmond LP, Shui JW, Davis B, Rich RR, Hu MC, Wange RL, Tan TH.

J Biol Chem. 2001 Jun 1;276(22):18908-14. Epub 2001 Mar 13.


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