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Reciprocal transcriptional regulation of metabolic and signaling pathways correlates with disease severity in heart failure.

Barth AS, Kumordzie A, Frangakis C, Margulies KB, Cappola TP, Tomaselli GF.

Circ Cardiovasc Genet. 2011 Oct;4(5):475-83. doi: 10.1161/CIRCGENETICS.110.957571. Epub 2011 Aug 9.


Dynamic gene expression patterns in animal models of early and late heart failure reveal biphasic-bidirectional transcriptional activation of signaling pathways.

Rowell J, Koitabashi N, Kass DA, Barth AS.

Physiol Genomics. 2014 Oct 15;46(20):779-87. doi: 10.1152/physiolgenomics.00054.2014. Epub 2014 Aug 26.


Transcriptomic profiling of the canine tachycardia-induced heart failure model: global comparison to human and murine heart failure.

Gao Z, Xu H, DiSilvestre D, Halperin VL, Tunin R, Tian Y, Yu W, Winslow RL, Tomaselli GF.

J Mol Cell Cardiol. 2006 Jan;40(1):76-86. Epub 2005 Oct 17.


Key pathways associated with heart failure development revealed by gene networks correlated with cardiac remodeling.

Gao Z, Barth AS, DiSilvestre D, Akar FG, Tian Y, Tanskanen A, Kass DA, Winslow RL, Tomaselli GF.

Physiol Genomics. 2008 Nov 12;35(3):222-30. doi: 10.1152/physiolgenomics.00100.2007. Epub 2008 Sep 9.


Reciprocal regulation of metabolic and signaling pathways.

Barth AS, Kumordzie A, Colantuoni C, Margulies KB, Cappola TP, Tomaselli GF.

BMC Genomics. 2010 Mar 24;11:197. doi: 10.1186/1471-2164-11-197.


Global gene expression profiling in the failing myocardium.

Asakura M, Kitakaze M.

Circ J. 2009 Sep;73(9):1568-76. Epub 2009 Jul 29. Review.


Mixed messages: transcription patterns in failing and recovering human myocardium.

Margulies KB, Matiwala S, Cornejo C, Olsen H, Craven WA, Bednarik D.

Circ Res. 2005 Mar 18;96(5):592-9. Epub 2005 Feb 17.


Energy metabolic reprogramming in the hypertrophied and early stage failing heart: a multisystems approach.

Lai L, Leone TC, Keller MP, Martin OJ, Broman AT, Nigro J, Kapoor K, Koves TR, Stevens R, Ilkayeva OR, Vega RB, Attie AD, Muoio DM, Kelly DP.

Circ Heart Fail. 2014 Nov;7(6):1022-31. doi: 10.1161/CIRCHEARTFAILURE.114.001469. Epub 2014 Sep 18.


Metabolic characterization of volume overload heart failure due to aorto-caval fistula in rats.

Melenovsky V, Benes J, Skaroupkova P, Sedmera D, Strnad H, Kolar M, Vlcek C, Petrak J, Benes J Jr, Papousek F, Oliyarnyk O, Kazdova L, Cervenka L.

Mol Cell Biochem. 2011 Aug;354(1-2):83-96. doi: 10.1007/s11010-011-0808-3. Epub 2011 Apr 5.


Secretogranin II; a protein increased in the myocardium and circulation in heart failure with cardioprotective properties.

Røsjø H, Stridsberg M, Florholmen G, Stensløkken KO, Ottesen AH, Sjaastad I, Husberg C, Dahl MB, Øie E, Louch WE, Omland T, Christensen G.

PLoS One. 2012;7(5):e37401. doi: 10.1371/journal.pone.0037401. Epub 2012 May 24.


Moderate severity heart failure does not involve a downregulation of myocardial fatty acid oxidation.

Chandler MP, Kerner J, Huang H, Vazquez E, Reszko A, Martini WZ, Hoppel CL, Imai M, Rastogi S, Sabbah HN, Stanley WC.

Am J Physiol Heart Circ Physiol. 2004 Oct;287(4):H1538-43. Epub 2004 Jun 10.


Cytokine expression profiling of the myocardium reveals a role for CX3CL1 (fractalkine) in heart failure.

Husberg C, Nygård S, Finsen AV, Damås JK, Frigessi A, Oie E, Waehre A, Gullestad L, Aukrust P, Yndestad A, Christensen G.

J Mol Cell Cardiol. 2008 Aug;45(2):261-9. doi: 10.1016/j.yjmcc.2008.05.009. Epub 2008 May 28.


Inducible NO synthase is constitutively expressed in porcine myocardium and its level decreases along with tachycardia-induced heart failure.

Paslawska U, Kiczak L, Bania J, Paslawski R, Janiszewski A, Dzięgiel P, Zacharski M, Tomaszek A, Michlik K.

Cardiovasc Pathol. 2016 Jan-Feb;25(1):3-11. doi: 10.1016/j.carpath.2015.08.003. Epub 2015 Aug 12.


Global gene expression analysis in nonfailing and failing myocardium pre- and postpulsatile and nonpulsatile ventricular assist device support.

Schwientek P, Ellinghaus P, Steppan S, D'Urso D, Seewald M, Kassner A, Cebulla R, Schulte-Eistrup S, Morshuis M, Röfe D, El Banayosy A, Körfer R, Milting H.

Physiol Genomics. 2010 Aug;42(3):397-405. doi: 10.1152/physiolgenomics.00030.2010. Epub 2010 May 11.


Cardiac resynchronization therapy restores sympathovagal balance in the failing heart by differential remodeling of cholinergic signaling.

DeMazumder D, Kass DA, O'Rourke B, Tomaselli GF.

Circ Res. 2015 May 8;116(10):1691-9. doi: 10.1161/CIRCRESAHA.116.305268. Epub 2015 Mar 2.


Induction of heart failure by minimally invasive aortic constriction in mice: reduced peroxisome proliferator-activated receptor γ coactivator levels and mitochondrial dysfunction.

Faerber G, Barreto-Perreia F, Schoepe M, Gilsbach R, Schrepper A, Schwarzer M, Mohr FW, Hein L, Doenst T.

J Thorac Cardiovasc Surg. 2011 Feb;141(2):492-500, 500.e1. doi: 10.1016/j.jtcvs.2010.03.029. Epub 2010 May 5.


The myocardial contractile response to physiological stress improves with high saturated fat feeding in heart failure.

Berthiaume JM, Bray MS, McElfresh TA, Chen X, Azam S, Young ME, Hoit BD, Chandler MP.

Am J Physiol Heart Circ Physiol. 2010 Aug;299(2):H410-21. doi: 10.1152/ajpheart.00270.2010. Epub 2010 May 28.


Myocardial G protein receptor-coupled kinase expression correlates with functional parameters and clinical severity in advanced heart failure.

Agüero J, Almenar L, Montó F, Oliver E, Sánchez-Lázaro I, Vicente D, Martínez-Dolz L, D'Ocon P, Rueda J, Salvador A.

J Card Fail. 2012 Jan;18(1):53-61. doi: 10.1016/j.cardfail.2011.10.008. Epub 2011 Nov 25.


[Adeno-associated viral gene transfer of SERCA2a improves heart function in chronic congestive heart failure rats].

Hui HP, Li XY, Liu XH, Sun S, Lu XC, Liu T, Yang W.

Zhonghua Xin Xue Guan Bing Za Zhi. 2006 Apr;34(4):357-62. Chinese.


[Overexpression of sarcoplasmic reticulum calcium ATPase induced hemodynamic and proteomic changes in a dog model of heart failure].

Fu ZQ, Li XY, Liu XH, Sun S, Liu T, Mi YF, Zhou SA, Ye WH, Wang QS.

Zhonghua Xin Xue Guan Bing Za Zhi. 2008 Mar;36(3):260-5. Chinese.


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