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Blunting of adaptive responses to resistance exercise training in women over 75y.

Greig CA, Gray C, Rankin D, Young A, Mann V, Noble B, Atherton PJ.

Exp Gerontol. 2011 Nov;46(11):884-90. doi: 10.1016/j.exger.2011.07.010. Epub 2011 Jul 28.


Synchronous deficits in cumulative muscle protein synthesis and ribosomal biogenesis underlie age-related anabolic resistance to exercise in humans.

Brook MS, Wilkinson DJ, Mitchell WK, Lund JN, Phillips BE, Szewczyk NJ, Greenhaff PL, Smith K, Atherton PJ.

J Physiol. 2016 Dec 15;594(24):7399-7417. doi: 10.1113/JP272857. Epub 2016 Nov 7.


Intake of branched-chain amino acids influences the levels of MAFbx mRNA and MuRF-1 total protein in resting and exercising human muscle.

Borgenvik M, Apró W, Blomstrand E.

Am J Physiol Endocrinol Metab. 2012 Mar 1;302(5):E510-21. doi: 10.1152/ajpendo.00353.2011. Epub 2011 Nov 29.


Aging Reduces the Activation of the mTORC1 Pathway after Resistance Exercise and Protein Intake in Human Skeletal Muscle: Potential Role of REDD1 and Impaired Anabolic Sensitivity.

Francaux M, Demeulder B, Naslain D, Fortin R, Lutz O, Caty G, Deldicque L.

Nutrients. 2016 Jan 15;8(1). pii: E47. doi: 10.3390/nu8010047.


Whey protein modifies gene expression related to protein metabolism affecting muscle weight in resistance-exercised rats.

Haraguchi FK, de Brito Magalhães CL, Neves LX, dos Santos RC, Pedrosa ML, Silva ME.

Nutrition. 2014 Jul-Aug;30(7-8):876-81. doi: 10.1016/j.nut.2013.12.007. Epub 2013 Dec 14.


Skeletal muscle amino acid transporter expression is increased in young and older adults following resistance exercise.

Drummond MJ, Fry CS, Glynn EL, Timmerman KL, Dickinson JM, Walker DK, Gundermann DM, Volpi E, Rasmussen BB.

J Appl Physiol (1985). 2011 Jul;111(1):135-42. doi: 10.1152/japplphysiol.01408.2010. Epub 2011 Apr 28.


Activation of mTOR signalling in young and old human skeletal muscle in response to combined resistance exercise and whey protein ingestion.

Farnfield MM, Breen L, Carey KA, Garnham A, Cameron-Smith D.

Appl Physiol Nutr Metab. 2012 Feb;37(1):21-30. doi: 10.1139/h11-132. Epub 2011 Dec 13.


Translational signaling responses preceding resistance training-mediated myofiber hypertrophy in young and old humans.

Mayhew DL, Kim JS, Cross JM, Ferrando AA, Bamman MM.

J Appl Physiol (1985). 2009 Nov;107(5):1655-62. doi: 10.1152/japplphysiol.91234.2008. Epub 2009 Jul 9.


Expression of growth-related genes in young and older human skeletal muscle following an acute stimulation of protein synthesis.

Drummond MJ, Miyazaki M, Dreyer HC, Pennings B, Dhanani S, Volpi E, Esser KA, Rasmussen BB.

J Appl Physiol (1985). 2009 Apr;106(4):1403-11. doi: 10.1152/japplphysiol.90842.2008. Epub 2008 Sep 11.


Resistance exercise training modulates acute gene expression during human skeletal muscle hypertrophy.

Nader GA, von Walden F, Liu C, Lindvall J, Gutmann L, Pistilli EE, Gordon PM.

J Appl Physiol (1985). 2014 Mar 15;116(6):693-702. doi: 10.1152/japplphysiol.01366.2013. Epub 2014 Jan 23.


REDD2 expression in rat skeletal muscle correlates with nutrient-induced activation of mTORC1: responses to aging, immobilization, and remobilization.

Kelleher AR, Pereira SL, Jefferson LS, Kimball SR.

Am J Physiol Endocrinol Metab. 2015 Jan 15;308(2):E122-9. doi: 10.1152/ajpendo.00341.2014. Epub 2014 Nov 18.


Resistance exercise induced mTORC1 signaling is not impaired by subsequent endurance exercise in human skeletal muscle.

Apró W, Wang L, Pontén M, Blomstrand E, Sahlin K.

Am J Physiol Endocrinol Metab. 2013 Jul 1;305(1):E22-32. doi: 10.1152/ajpendo.00091.2013. Epub 2013 Apr 30.


Acute molecular responses in untrained and trained muscle subjected to aerobic and resistance exercise training versus resistance training alone.

Fernandez-Gonzalo R, Lundberg TR, Tesch PA.

Acta Physiol (Oxf). 2013 Dec;209(4):283-94. doi: 10.1111/apha.12174.


The effects of resistance exercise training on macro- and micro-circulatory responses to feeding and skeletal muscle protein anabolism in older men.

Phillips BE, Atherton PJ, Varadhan K, Limb MC, Wilkinson DJ, Sjøberg KA, Smith K, Williams JP.

J Physiol. 2015 Jun 15;593(12):2721-34. doi: 10.1113/JP270343. Epub 2015 May 14.


Protein ingestion increases myofibrillar protein synthesis after concurrent exercise.

Camera DM, West DW, Phillips SM, Rerecich T, Stellingwerff T, Hawley JA, Coffey VG.

Med Sci Sports Exerc. 2015 Jan;47(1):82-91. doi: 10.1249/MSS.0000000000000390.


Exercise training attenuates MuRF-1 expression in the skeletal muscle of patients with chronic heart failure independent of age: the randomized Leipzig Exercise Intervention in Chronic Heart Failure and Aging catabolism study.

Gielen S, Sandri M, Kozarez I, Kratzsch J, Teupser D, Thiery J, Erbs S, Mangner N, Lenk K, Hambrecht R, Schuler G, Adams V.

Circulation. 2012 Jun 5;125(22):2716-27. doi: 10.1161/CIRCULATIONAHA.111.047381. Epub 2012 May 7.


Blood flow restriction exercise stimulates mTORC1 signaling and muscle protein synthesis in older men.

Fry CS, Glynn EL, Drummond MJ, Timmerman KL, Fujita S, Abe T, Dhanani S, Volpi E, Rasmussen BB.

J Appl Physiol (1985). 2010 May;108(5):1199-209. doi: 10.1152/japplphysiol.01266.2009. Epub 2010 Feb 11.


Proteolytic gene expression differs at rest and after resistance exercise between young and old women.

Raue U, Slivka D, Jemiolo B, Hollon C, Trappe S.

J Gerontol A Biol Sci Med Sci. 2007 Dec;62(12):1407-12.


Reduced REDD1 expression contributes to activation of mTORC1 following electrically induced muscle contraction.

Gordon BS, Steiner JL, Lang CH, Jefferson LS, Kimball SR.

Am J Physiol Endocrinol Metab. 2014 Oct 15;307(8):E703-11. doi: 10.1152/ajpendo.00250.2014. Epub 2014 Aug 26.


Emerging role for regulated in development and DNA damage 1 (REDD1) in the regulation of skeletal muscle metabolism.

Gordon BS, Steiner JL, Williamson DL, Lang CH, Kimball SR.

Am J Physiol Endocrinol Metab. 2016 Jul 1;311(1):E157-74. doi: 10.1152/ajpendo.00059.2016. Epub 2016 May 17. Review.

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