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Items: 1 to 20 of 153

2.

Mitochondria as a target in the therapeutic properties of curcumin.

Trujillo J, Granados-Castro LF, Zazueta C, Andérica-Romero AC, Chirino YI, Pedraza-Chaverrí J.

Arch Pharm (Weinheim). 2014 Dec;347(12):873-84. doi: 10.1002/ardp.201400266. Epub 2014 Sep 22. Review.

PMID:
25243820
3.

The Nrf2-ARE Signalling pathway: promising drug target to combat oxidative stress in neurodegenerative disorders.

van Muiswinkel FL, Kuiperij HB.

Curr Drug Targets CNS Neurol Disord. 2005 Jun;4(3):267-81. Review.

PMID:
15975029
4.

Fumaric acid esters exert neuroprotective effects in neuroinflammation via activation of the Nrf2 antioxidant pathway.

Linker RA, Lee DH, Ryan S, van Dam AM, Conrad R, Bista P, Zeng W, Hronowsky X, Buko A, Chollate S, Ellrichmann G, Brück W, Dawson K, Goelz S, Wiese S, Scannevin RH, Lukashev M, Gold R.

Brain. 2011 Mar;134(Pt 3):678-92. doi: 10.1093/brain/awq386.

PMID:
21354971
5.

Nrf2-induced antioxidant protection: a promising target to counteract ROS-mediated damage in neurodegenerative disease?

de Vries HE, Witte M, Hondius D, Rozemuller AJ, Drukarch B, Hoozemans J, van Horssen J.

Free Radic Biol Med. 2008 Nov 15;45(10):1375-83. doi: 10.1016/j.freeradbiomed.2008.09.001. Epub 2008 Sep 13. Review.

PMID:
18824091
6.
7.

Oxidative stress, mitochondrial dysfunction and cellular stress response in Friedreich's ataxia.

Calabrese V, Lodi R, Tonon C, D'Agata V, Sapienza M, Scapagnini G, Mangiameli A, Pennisi G, Stella AM, Butterfield DA.

J Neurol Sci. 2005 Jun 15;233(1-2):145-62. Review.

PMID:
15896810
8.

SMN deficiency does not induce oxidative stress in SMA iPSC-derived astrocytes or motor neurons.

Patitucci TN, Ebert AD.

Hum Mol Genet. 2016 Feb 1;25(3):514-23. doi: 10.1093/hmg/ddv489. Epub 2015 Dec 7.

PMID:
26643950
9.

Up-regulation of aldose reductase expression mediated by phosphatidylinositol 3-kinase/Akt and Nrf2 is involved in the protective effect of curcumin against oxidative damage.

Kang ES, Woo IS, Kim HJ, Eun SY, Paek KS, Kim HJ, Chang KC, Lee JH, Lee HT, Kim JH, Nishinaka T, Yabe-Nishimura C, Seo HG.

Free Radic Biol Med. 2007 Aug 15;43(4):535-45. Epub 2007 May 16.

PMID:
17640564
10.

Fumarates promote cytoprotection of central nervous system cells against oxidative stress via the nuclear factor (erythroid-derived 2)-like 2 pathway.

Scannevin RH, Chollate S, Jung MY, Shackett M, Patel H, Bista P, Zeng W, Ryan S, Yamamoto M, Lukashev M, Rhodes KJ.

J Pharmacol Exp Ther. 2012 Apr;341(1):274-84. doi: 10.1124/jpet.111.190132. Epub 2012 Jan 20.

11.

Curcumin ameliorates dopaminergic neuronal oxidative damage via activation of the Akt/Nrf2 pathway.

Cui Q, Li X, Zhu H.

Mol Med Rep. 2016 Feb;13(2):1381-8. doi: 10.3892/mmr.2015.4657. Epub 2015 Dec 8.

PMID:
26648392
12.

Fibroblast growth factor-1 induces heme oxygenase-1 via nuclear factor erythroid 2-related factor 2 (Nrf2) in spinal cord astrocytes: consequences for motor neuron survival.

Vargas MR, Pehar M, Cassina P, Martínez-Palma L, Thompson JA, Beckman JS, Barbeito L.

J Biol Chem. 2005 Jul 8;280(27):25571-9. Epub 2005 May 3.

13.

Prevention of glutamate excitotoxicity in motor neurons by 5,6-dihydrocyclopenta-1,2-dithiole-3-thione: implication to the development of neuroprotective drugs.

Li CY, Liu XY, Bu H, Li Z, Li B, Sun MM, Guo YS, Liu YL, Zhang Y.

Cell Mol Life Sci. 2007 Jul;64(14):1861-9.

PMID:
17530460
14.

Eriodictyol-7-O-glucoside activates Nrf2 and protects against cerebral ischemic injury.

Jing X, Ren D, Wei X, Shi H, Zhang X, Perez RG, Lou H, Lou H.

Toxicol Appl Pharmacol. 2013 Dec 15;273(3):672-9.

PMID:
24466583
15.
16.

Diterpenoids isolated from Sideritis species protect astrocytes against oxidative stress via Nrf2.

González-Burgos E, Carretero ME, Gómez-Serranillos MP.

J Nat Prod. 2012 Oct 26;75(10):1750-8. doi: 10.1021/np300418m. Epub 2012 Oct 9.

PMID:
23046382
17.

Involvement of Nrf2 signaling pathway in the neuroprotective activity of natural kaurane diterpenes.

González-Burgos E, Carretero ME, Gómez-Serranillos MP.

Neuroscience. 2013 Feb 12;231:400-12. doi: 10.1016/j.neuroscience.2012.10.018. Epub 2012 Oct 16. Erratum in: Neuroscience. 2014 Jun6;269():131.

PMID:
23079631
18.

Mechanisms of oxidative damage in multiple sclerosis and neurodegenerative diseases: therapeutic modulation via fumaric acid esters.

Lee DH, Gold R, Linker RA.

Int J Mol Sci. 2012;13(9):11783-803. doi: 10.3390/ijms130911783. Epub 2012 Sep 18.

19.
20.

The Nrf2-ARE cytoprotective pathway in astrocytes.

Vargas MR, Johnson JA.

Expert Rev Mol Med. 2009 Jun 3;11:e17. doi: 10.1017/S1462399409001094. Review.

PMID:
19490732

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