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Items: 1 to 20 of 109

1.

Conantokin-G: a novel peptide antagonist to the N-methyl-D-aspartic acid (NMDA) receptor.

Mena EE, Gullak MF, Pagnozzi MJ, Richter KE, Rivier J, Cruz LJ, Olivera BM.

Neurosci Lett. 1990 Oct 16;118(2):241-4.

PMID:
2177176
2.

Noncompetitive inhibition of N-methyl-D-aspartate by conantokin-G: evidence for an allosteric interaction at polyamine sites.

Skolnick P, Boje K, Miller R, Pennington M, Maccecchini ML.

J Neurochem. 1992 Oct;59(4):1516-21.

PMID:
1328523
3.

Synthetic analogues of conantokin-G: NMDA antagonists acting through a novel polyamine-coupled site.

Zhou LM, Szendrei GI, Fossom LH, Maccecchini ML, Skolnick P, Otvos L Jr.

J Neurochem. 1996 Feb;66(2):620-8.

PMID:
8592132
4.

Characterization of 3-carboxy-5-phosphono-1,2,3,4-tetrahydroisoquinoline (SC-48981), a potent competitive N-methy-D-aspartate (NMDA) receptor antagonist, in vitro and in vivo.

Vazquez ML, Garland DJ, Sun ET, Cler JA, Mick SJ, Hood WF, Monahan JB, Iyengar S, Rao TS.

Neurosci Lett. 1992 Feb 3;135(2):149-52.

PMID:
1352628
5.

Conantokin-G selectively inhibits N-methyl-D-aspartate-induced currents in Xenopus oocytes injected with mouse brain mRNA.

Hammerland LG, Olivera BM, Yoshikami D.

Eur J Pharmacol. 1992 Jul 1;226(3):239-44.

PMID:
1358659
6.

Conantokin-G antagonism of the NMDA receptor subtype expressed in cultured cerebellar granule cells.

Haack JA, Parks TN, Olivera BM.

Neurosci Lett. 1993 Nov 26;163(1):63-6.

PMID:
7905198
7.

CPP, a selective N-methyl-D-aspartate (NMDA)-type receptor antagonist: characterization in vitro and in vivo.

Lehmann J, Schneider J, McPherson S, Murphy DE, Bernard P, Tsai C, Bennett DA, Pastor G, Steel DJ, Boehm C, et al.

J Pharmacol Exp Ther. 1987 Mar;240(3):737-46.

PMID:
2882014
8.

Ifenprodil and SL 82.0715 as cerebral anti-ischemic agents. II. Evidence for N-methyl-D-aspartate receptor antagonist properties.

Carter C, Benavides J, Legendre P, Vincent JD, Noel F, Thuret F, Lloyd KG, Arbilla S, Zivkovic B, MacKenzie ET, et al.

J Pharmacol Exp Ther. 1988 Dec;247(3):1222-32.

PMID:
2849669
9.
10.

Polyamine-like actions of peptides derived from conantokin-G, an N-methyl-D-aspartate (NMDA) antagonist.

Chandler P, Pennington M, Maccecchini ML, Nashed NT, Skolnick P.

J Biol Chem. 1993 Aug 15;268(23):17173-8.

11.

Structure-activity studies of conantokins as human N-methyl-D-aspartate receptor modulators.

Nielsen KJ, Skjaerbaek N, Dooley M, Adams DA, Mortensen M, Dodd PR, Craik DJ, Alewood PF, Lewis RJ.

J Med Chem. 1999 Feb 11;42(3):415-26.

PMID:
9986713
12.

In vitro and in vivo characterization of conantokin-R, a selective NMDA receptor antagonist isolated from the venom of the fish-hunting snail Conus radiatus.

White HS, McCabe RT, Armstrong H, Donevan SD, Cruz LJ, Abogadie FC, Torres J, Rivier JE, Paarmann I, Hollmann M, Olivera BM.

J Pharmacol Exp Ther. 2000 Jan;292(1):425-32.

13.

Role of gamma-carboxyglutamic acid in the calcium-induced structural transition of conantokin G, a conotoxin from the marine snail Conus geographus.

Rigby AC, Baleja JD, Li L, Pedersen LG, Furie BC, Furie B.

Biochemistry. 1997 Dec 16;36(50):15677-84.

PMID:
9398296
14.

Pharmacological characterization of LY233053: a structurally novel tetrazole-substituted competitive N-methyl-D-aspartic acid antagonist with a short duration of action.

Schoepp DD, Ornstein PL, Leander JD, Lodge D, Salhoff CR, Zeman S, Zimmerman DM.

J Pharmacol Exp Ther. 1990 Dec;255(3):1301-8.

PMID:
2148188
15.

Point mutations identify the glutamate binding pocket of the N-methyl-D-aspartate receptor as major site of conantokin-G inhibition.

Wittekindt B, Malany S, Schemm R, Otvos L, Maccecchini ML, Laube B, Betz H.

Neuropharmacology. 2001 Nov;41(6):753-61.

PMID:
11640930
16.

The antidepressant metapramine is a low-affinity antagonist at N-methyl-D-aspartic acid receptors.

Boireau A, Bordier F, Durand G, Doble A.

Neuropharmacology. 1996;35(12):1703-7.

PMID:
9076749
17.

Pharmacological characterization of MDL 105,519, an NMDA receptor glycine site antagonist.

Baron BM, Harrison BL, Kehne JH, Schmidt CJ, van Giersbergen PL, White HS, Siegel BW, Senyah Y, McCloskey TC, Fadayel GM, Taylor VL, Murawsky MK, Nyce P, Salituro FG.

Eur J Pharmacol. 1997 Apr 4;323(2-3):181-92.

PMID:
9128837
18.

Structure-function relationships of the NMDA receptor antagonist peptide, conantokin-R.

Blandl T, Warder SE, Prorok M, Castellino FJ.

FEBS Lett. 2000 Mar 24;470(2):139-46.

19.

Inhibition of NMDA-induced currents by conantokin-G and conantokin-T in cultured embryonic murine hippocampal neurons.

Klein RC, Galdzicki Z, Castellino FJ.

Neuropharmacology. 1999 Dec;38(12):1819-29.

PMID:
10608277
20.

Guanine nucleotides are competitive inhibitors of N-methyl-D-aspartate at its receptor site both in vitro and in vivo.

Baron BM, Dudley MW, McCarty DR, Miller FP, Reynolds IJ, Schmidt CJ.

J Pharmacol Exp Ther. 1989 Jul;250(1):162-9.

PMID:
2545857
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