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Items: 1 to 20 of 114

1.

LXRα regulates macrophage arginase 1 through PU.1 and interferon regulatory factor 8.

Pourcet B, Feig JE, Vengrenyuk Y, Hobbs AJ, Kepka-Lenhart D, Garabedian MJ, Morris SM Jr, Fisher EA, Pineda-Torra I.

Circ Res. 2011 Aug 19;109(5):492-501. doi: 10.1161/CIRCRESAHA.111.241810. Epub 2011 Jul 14.

2.

Transcriptional regulation of macrophage arginase 1 expression and its role in atherosclerosis.

Pourcet B, Pineda-Torra I.

Trends Cardiovasc Med. 2013 Jul;23(5):143-52. doi: 10.1016/j.tcm.2012.10.003. Epub 2013 Jan 30. Review.

PMID:
23375628
4.

PU.1 and ICSBP control constitutive and IFN-gamma-regulated Tlr9 gene expression in mouse macrophages.

Schroder K, Lichtinger M, Irvine KM, Brion K, Trieu A, Ross IL, Ravasi T, Stacey KJ, Rehli M, Hume DA, Sweet MJ.

J Leukoc Biol. 2007 Jun;81(6):1577-90. Epub 2007 Mar 14.

PMID:
17360957
5.

Multiple Ets factors and interferon regulatory factor-4 modulate CD68 expression in a cell type-specific manner.

O'Reilly D, Quinn CM, El-Shanawany T, Gordon S, Greaves DR.

J Biol Chem. 2003 Jun 13;278(24):21909-19. Epub 2003 Apr 3.

6.

Regulation of macrophage arginase expression and tumor growth by the Ron receptor tyrosine kinase.

Sharda DR, Yu S, Ray M, Squadrito ML, De Palma M, Wynn TA, Morris SM Jr, Hankey PA.

J Immunol. 2011 Sep 1;187(5):2181-92. doi: 10.4049/jimmunol.1003460. Epub 2011 Aug 1.

7.

Phosphorylation of IRF8 in a pre-associated complex with Spi-1/PU.1 and non-phosphorylated Stat1 is critical for LPS induction of the IL1B gene.

Unlu S, Kumar A, Waterman WR, Tsukada J, Wang KZ, Galson DL, Auron PE.

Mol Immunol. 2007 Jul;44(13):3364-79. Epub 2007 Mar 26.

8.
9.

Modulation of Macrophage Gene Expression via Liver X Receptor α Serine 198 Phosphorylation.

Wu C, Hussein MA, Shrestha E, Leone S, Aiyegbo MS, Lambert WM, Pourcet B, Cardozo T, Gustafson JA, Fisher EA, Pineda-Torra I, Garabedian MJ.

Mol Cell Biol. 2015 Jun 1;35(11):2024-34. doi: 10.1128/MCB.00985-14. Epub 2015 Mar 30.

10.

Macrophage fatty-acid synthase deficiency decreases diet-induced atherosclerosis.

Schneider JG, Yang Z, Chakravarthy MV, Lodhi IJ, Wei X, Turk J, Semenkovich CF.

J Biol Chem. 2010 Jul 23;285(30):23398-409. doi: 10.1074/jbc.M110.100321. Epub 2010 May 17.

11.

Genome-wide analysis of LXRα activation reveals new transcriptional networks in human atherosclerotic foam cells.

Feldmann R, Fischer C, Kodelja V, Behrens S, Haas S, Vingron M, Timmermann B, Geikowski A, Sauer S.

Nucleic Acids Res. 2013 Apr 1;41(6):3518-31. doi: 10.1093/nar/gkt034. Epub 2013 Feb 7.

12.

Adipocyte enhancer-binding protein 1 (AEBP1) (a novel macrophage proinflammatory mediator) overexpression promotes and ablation attenuates atherosclerosis in ApoE (-/-) and LDLR (-/-) mice.

Bogachev O, Majdalawieh A, Pan X, Zhang L, Ro HS.

Mol Med. 2011 Sep-Oct;17(9-10):1056-64. doi: 10.2119/molmed.2011.00141. Epub 2011 Jun 14.

13.

Progressive visceral leishmaniasis is driven by dominant parasite-induced STAT6 activation and STAT6-dependent host arginase 1 expression.

Osorio EY, Zhao W, Espitia C, Saldarriaga O, Hawel L, Byus CV, Travi BL, Melby PC.

PLoS Pathog. 2012 Jan;8(1):e1002417. doi: 10.1371/journal.ppat.1002417. Epub 2012 Jan 19.

14.

Macrophage LXRα gene therapy ameliorates atherosclerosis as well as hypertriglyceridemia in LDLR(-/-) mice.

Li G, Biju KC, Xu X, Zhou Q, Chen C, Valente AJ, He W, Reddick RL, Freeman GL, Ahuja SS, Clark RA, Li S.

Gene Ther. 2011 Aug;18(8):835-41. doi: 10.1038/gt.2011.29. Epub 2011 Mar 10.

PMID:
21390069
15.

PAPP-A negatively regulates ABCA1, ABCG1 and SR-B1 expression by inhibiting LXRα through the IGF-I-mediated signaling pathway.

Tang SL, Chen WJ, Yin K, Zhao GJ, Mo ZC, Lv YC, Ouyang XP, Yu XH, Kuang HJ, Jiang ZS, Fu YC, Tang CK.

Atherosclerosis. 2012 Jun;222(2):344-54. doi: 10.1016/j.atherosclerosis.2012.03.005. Epub 2012 Mar 27.

PMID:
22503545
16.

Suppression of Il-12 transcription in macrophages following Fc gamma receptor ligation.

Grazia Cappiello M, Sutterwala FS, Trinchieri G, Mosser DM, Ma X.

J Immunol. 2001 Apr 1;166(7):4498-506.

17.

LXR promotes the maximal egress of monocyte-derived cells from mouse aortic plaques during atherosclerosis regression.

Feig JE, Pineda-Torra I, Sanson M, Bradley MN, Vengrenyuk Y, Bogunovic D, Gautier EL, Rubinstein D, Hong C, Liu J, Wu C, van Rooijen N, Bhardwaj N, Garabedian M, Tontonoz P, Fisher EA.

J Clin Invest. 2010 Dec;120(12):4415-24. doi: 10.1172/JCI38911.

18.

Genetic deletion of LXRα prevents arsenic-enhanced atherosclerosis, but not arsenic-altered plaque composition.

Lemaire M, Lemarié CA, Flores Molina M, Guilbert C, Lehoux S, Mann KK.

Toxicol Sci. 2014 Dec;142(2):477-88. doi: 10.1093/toxsci/kfu197. Epub 2014 Sep 30.

19.
20.

Panax notoginseng saponins attenuate atherosclerosis via reciprocal regulation of lipid metabolism and inflammation by inducing liver X receptor alpha expression.

Fan JS, Liu DN, Huang G, Xu ZZ, Jia Y, Zhang HG, Li XH, He FT.

J Ethnopharmacol. 2012 Aug 1;142(3):732-8. doi: 10.1016/j.jep.2012.05.053. Epub 2012 Jun 7.

PMID:
22683903

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