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Items: 1 to 20 of 81

1.

Regulatory domain selectivity in the cell-type specific PKN-dependence of cell migration.

Lachmann S, Jevons A, De Rycker M, Casamassima A, Radtke S, Collazos A, Parker PJ.

PLoS One. 2011;6(7):e21732. doi: 10.1371/journal.pone.0021732. Epub 2011 Jul 6.

2.

Purification and kinase assay of PKN.

Mukai H, Ono Y.

Methods Enzymol. 2006;406:234-50.

PMID:
16472661
3.

Phosphorylation of protein kinase N by phosphoinositide-dependent protein kinase-1 mediates insulin signals to the actin cytoskeleton.

Dong LQ, Landa LR, Wick MJ, Zhu L, Mukai H, Ono Y, Liu F.

Proc Natl Acad Sci U S A. 2000 May 9;97(10):5089-94.

4.

Site recognition and substrate screens for PKN family proteins.

Collazos A, Michael N, Whelan RD, Kelly G, Mellor H, Pang LC, Totty N, Parker PJ.

Biochem J. 2011 Sep 15;438(3):535-43. doi: 10.1042/BJ20110521.

PMID:
21749319
5.

Autocrine CCL2 promotes cell migration and invasion via PKC activation and tyrosine phosphorylation of paxillin in bladder cancer cells.

Chiu HY, Sun KH, Chen SY, Wang HH, Lee MY, Tsou YC, Jwo SC, Sun GH, Tang SJ.

Cytokine. 2012 Aug;59(2):423-32. doi: 10.1016/j.cyto.2012.04.017. Epub 2012 May 20.

PMID:
22617682
7.
8.

Protein kinase N (PKN) and PKN-related protein rhophilin as targets of small GTPase Rho.

Watanabe G, Saito Y, Madaule P, Ishizaki T, Fujisawa K, Morii N, Mukai H, Ono Y, Kakizuka A, Narumiya S.

Science. 1996 Feb 2;271(5249):645-8.

PMID:
8571126
9.
10.

Hyaluronan-CD44 interaction stimulates Rac1 signaling and PKN gamma kinase activation leading to cytoskeleton function and cell migration in astrocytes.

Bourguignon LY, Gilad E, Peyrollier K, Brightman A, Swanson RA.

J Neurochem. 2007 May;101(4):1002-17. Epub 2007 Mar 30.

11.

Development of an intracellularly acting inhibitory peptide selective for PKN.

Shiga K, Takayama K, Futaki S, Hutti JE, Cantley LC, Ueki K, Ono Y, Mukai H.

Biochem J. 2009 Dec 23;425(2):445-53. doi: 10.1042/BJ20090380.

12.
13.

Knockout of the PKN Family of Rho Effector Kinases Reveals a Non-redundant Role for PKN2 in Developmental Mesoderm Expansion.

Qu├ętier I, Marshall JJ, Spencer-Dene B, Lachmann S, Casamassima A, Franco C, Escuin S, Worrall JT, Baskaran P, Rajeeve V, Howell M, Copp AJ, Stamp G, Rosewell I, Cutillas P, Gerhardt H, Parker PJ, Cameron AJ.

Cell Rep. 2016 Jan 26;14(3):440-8. doi: 10.1016/j.celrep.2015.12.049. Epub 2016 Jan 7.

14.

Blocking tumor cell migration and invasion with biphenyl isoxazole derivative KRIBB3, a synthetic molecule that inhibits Hsp27 phosphorylation.

Shin KD, Lee MY, Shin DS, Lee S, Son KH, Koh S, Paik YK, Kwon BM, Han DC.

J Biol Chem. 2005 Dec 16;280(50):41439-48. Epub 2005 Oct 18.

15.
17.

Protein Kinase C-Related Kinase (PKN/PRK). Potential Key-Role for PKN1 in Protection of Hypoxic Neurons.

Thauerer B, Zur Nedden S, Baier-Bitterlich G.

Curr Neuropharmacol. 2014 May;12(3):213-8. doi: 10.2174/1570159X11666131225000518.

18.

The interaction of PKN3 with RhoC promotes malignant growth.

Unsal-Kacmaz K, Ragunathan S, Rosfjord E, Dann S, Upeslacis E, Grillo M, Hernandez R, Mack F, Klippel A.

Mol Oncol. 2012 Jun;6(3):284-98. doi: 10.1016/j.molonc.2011.12.001. Epub 2011 Dec 28.

19.

Downregulation of integrin-linked kinase inhibits epithelial-to-mesenchymal transition and metastasis in bladder cancer cells.

Zhu J, Pan X, Zhang Z, Gao J, Zhang L, Chen J.

Cell Signal. 2012 Jun;24(6):1323-32.

PMID:
22570869
20.

Signal transduction by protein kinase C in mammalian cells.

Kanashiro CA, Khalil RA.

Clin Exp Pharmacol Physiol. 1998 Dec;25(12):974-85. Review.

PMID:
9887993

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