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Items: 1 to 20 of 147

1.

Dicer recognizes the 5' end of RNA for efficient and accurate processing.

Park JE, Heo I, Tian Y, Simanshu DK, Chang H, Jee D, Patel DJ, Kim VN.

Nature. 2011 Jul 13;475(7355):201-5. doi: 10.1038/nature10198.

2.

A universal small molecule, inorganic phosphate, restricts the substrate specificity of Dicer-2 in small RNA biogenesis.

Fukunaga R, Zamore PD.

Cell Cycle. 2014;13(11):1671-6. doi: 10.4161/cc.29066. Epub 2014 Apr 30.

3.

Inorganic phosphate blocks binding of pre-miRNA to Dicer-2 via its PAZ domain.

Fukunaga R, Colpan C, Han BW, Zamore PD.

EMBO J. 2014 Feb 18;33(4):371-84. doi: 10.1002/embj.201387176. Epub 2014 Jan 31.

4.

Recognition of the pre-miRNA structure by Drosophila Dicer-1.

Tsutsumi A, Kawamata T, Izumi N, Seitz H, Tomari Y.

Nat Struct Mol Biol. 2011 Sep 18;18(10):1153-8. doi: 10.1038/nsmb.2125.

PMID:
21926993
5.

Substrate-specific kinetics of Dicer-catalyzed RNA processing.

Chakravarthy S, Sternberg SH, Kellenberger CA, Doudna JA.

J Mol Biol. 2010 Dec 3;404(3):392-402. doi: 10.1016/j.jmb.2010.09.030. Epub 2010 Oct 13.

6.

Short RNA duplexes guide sequence-dependent cleavage by human Dicer.

Bergeron L Jr, Perreault JP, Abou Elela S.

RNA. 2010 Dec;16(12):2464-73. doi: 10.1261/rna.2346510. Epub 2010 Oct 25.

7.

Coordinated activities of human dicer domains in regulatory RNA processing.

Ma E, Zhou K, Kidwell MA, Doudna JA.

J Mol Biol. 2012 Sep 28;422(4):466-76. doi: 10.1016/j.jmb.2012.06.009. Epub 2012 Jun 19.

8.

Phosphate and R2D2 restrict the substrate specificity of Dicer-2, an ATP-driven ribonuclease.

Cenik ES, Fukunaga R, Lu G, Dutcher R, Wang Y, Tanaka Hall TM, Zamore PD.

Mol Cell. 2011 Apr 22;42(2):172-84. doi: 10.1016/j.molcel.2011.03.002. Epub 2011 Mar 17.

9.

MCPIP1 ribonuclease antagonizes dicer and terminates microRNA biogenesis through precursor microRNA degradation.

Suzuki HI, Arase M, Matsuyama H, Choi YL, Ueno T, Mano H, Sugimoto K, Miyazono K.

Mol Cell. 2011 Nov 4;44(3):424-36. doi: 10.1016/j.molcel.2011.09.012.

10.

A comprehensive analysis of precursor microRNA cleavage by human Dicer.

Feng Y, Zhang X, Graves P, Zeng Y.

RNA. 2012 Nov;18(11):2083-92. doi: 10.1261/rna.033688.112. Epub 2012 Sep 14.

11.

Two-step cleavage of hairpin RNA with 5' overhangs by human DICER.

Ando Y, Maida Y, Morinaga A, Burroughs AM, Kimura R, Chiba J, Suzuki H, Masutomi K, Hayashizaki Y.

BMC Mol Biol. 2011 Feb 9;12:6. doi: 10.1186/1471-2199-12-6.

12.

Distinct roles for Drosophila Dicer-1 and Dicer-2 in the siRNA/miRNA silencing pathways.

Lee YS, Nakahara K, Pham JW, Kim K, He Z, Sontheimer EJ, Carthew RW.

Cell. 2004 Apr 2;117(1):69-81.

13.

Single processing center models for human Dicer and bacterial RNase III.

Zhang H, Kolb FA, Jaskiewicz L, Westhof E, Filipowicz W.

Cell. 2004 Jul 9;118(1):57-68.

14.

Dicer partner proteins tune the length of mature miRNAs in flies and mammals.

Fukunaga R, Han BW, Hung JH, Xu J, Weng Z, Zamore PD.

Cell. 2012 Oct 26;151(3):533-46. doi: 10.1016/j.cell.2012.09.027. Epub 2012 Oct 11. Erratum in: Cell. 2012 Nov 9;151(4):912.

15.

A role for the Dicer helicase domain in the processing of thermodynamically unstable hairpin RNAs.

Soifer HS, Sano M, Sakurai K, Chomchan P, Saetrom P, Sherman MA, Collingwood MA, Behlke MA, Rossi JJ.

Nucleic Acids Res. 2008 Nov;36(20):6511-22. doi: 10.1093/nar/gkn687. Epub 2008 Oct 15.

16.

Dicer-TRBP complex formation ensures accurate mammalian microRNA biogenesis.

Wilson RC, Tambe A, Kidwell MA, Noland CL, Schneider CP, Doudna JA.

Mol Cell. 2015 Feb 5;57(3):397-407. doi: 10.1016/j.molcel.2014.11.030. Epub 2014 Dec 31.

17.

The contributions of dsRNA structure to Dicer specificity and efficiency.

Vermeulen A, Behlen L, Reynolds A, Wolfson A, Marshall WS, Karpilow J, Khvorova A.

RNA. 2005 May;11(5):674-82. Epub 2005 Apr 5.

18.

RNase III-independent microRNA biogenesis in mammalian cells.

Maurin T, Cazalla D, Yang S Jr, Bortolamiol-Becet D, Lai EC.

RNA. 2012 Dec;18(12):2166-73. doi: 10.1261/rna.036194.112. Epub 2012 Oct 24.

19.

Re-evaluation of the roles of DROSHA, Export in 5, and DICER in microRNA biogenesis.

Kim YK, Kim B, Kim VN.

Proc Natl Acad Sci U S A. 2016 Mar 29;113(13):E1881-9. doi: 10.1073/pnas.1602532113. Epub 2016 Mar 14.

20.

Processing of pre-microRNAs by the Dicer-1-Loquacious complex in Drosophila cells.

Saito K, Ishizuka A, Siomi H, Siomi MC.

PLoS Biol. 2005 Jul;3(7):e235. Epub 2005 May 24.

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