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Items: 1 to 20 of 106

1.

Architecture of the Mediator head module.

Imasaki T, Calero G, Cai G, Tsai KL, Yamada K, Cardelli F, Erdjument-Bromage H, Tempst P, Berger I, Kornberg GL, Asturias FJ, Kornberg RD, Takagi Y.

Nature. 2011 Jul 3;475(7355):240-3. doi: 10.1038/nature10162.

2.

Structure of the Mediator head module.

Larivière L, Plaschka C, Seizl M, Wenzeck L, Kurth F, Cramer P.

Nature. 2012 Dec 20;492(7429):448-51. doi: 10.1038/nature11670. Epub 2012 Oct 31.

PMID:
23123849
3.

Architecture of the RNA polymerase II-Mediator core initiation complex.

Plaschka C, Larivière L, Wenzeck L, Seizl M, Hemann M, Tegunov D, Petrotchenko EV, Borchers CH, Baumeister W, Herzog F, Villa E, Cramer P.

Nature. 2015 Feb 19;518(7539):376-80. doi: 10.1038/nature14229. Epub 2015 Feb 4.

PMID:
25652824
4.

Structure of a Complete Mediator-RNA Polymerase II Pre-Initiation Complex.

Robinson PJ, Trnka MJ, Bushnell DA, Davis RE, Mattei PJ, Burlingame AL, Kornberg RD.

Cell. 2016 Sep 8;166(6):1411-1422.e16. doi: 10.1016/j.cell.2016.08.050.

PMID:
27610567
5.

p53 activates transcription by directing structural shifts in Mediator.

Meyer KD, Lin SC, Bernecky C, Gao Y, Taatjes DJ.

Nat Struct Mol Biol. 2010 Jun;17(6):753-60. doi: 10.1038/nsmb.1816. Epub 2010 May 9.

6.

Mediator-dependent recruitment of TFIIH modules in preinitiation complex.

Esnault C, Ghavi-Helm Y, Brun S, Soutourina J, Van Berkum N, Boschiero C, Holstege F, Werner M.

Mol Cell. 2008 Aug 8;31(3):337-46. doi: 10.1016/j.molcel.2008.06.021.

7.

Facilitated assembly of the preinitiation complex by separated tail and head/middle modules of the mediator.

Galdieri L, Desai P, Vancura A.

J Mol Biol. 2012 Jan 20;415(3):464-74. doi: 10.1016/j.jmb.2011.11.020. Epub 2011 Nov 23.

8.

Molecular architecture of the human Mediator-RNA polymerase II-TFIIF assembly.

Bernecky C, Grob P, Ebmeier CC, Nogales E, Taatjes DJ.

PLoS Biol. 2011 Mar;9(3):e1000603. doi: 10.1371/journal.pbio.1000603. Epub 2011 Mar 29.

9.

Med19(Rox3) regulates Intermodule interactions in the Saccharomyces cerevisiae mediator complex.

Baidoobonso SM, Guidi BW, Myers LC.

J Biol Chem. 2007 Feb 23;282(8):5551-9. Epub 2006 Dec 27.

10.

Preparation and topology of the Mediator middle module.

Koschubs T, Lorenzen K, Baumli S, Sandström S, Heck AJ, Cramer P.

Nucleic Acids Res. 2010 Jun;38(10):3186-95. doi: 10.1093/nar/gkq029. Epub 2010 Jan 31.

11.

Mediator head module structure and functional interactions.

Cai G, Imasaki T, Yamada K, Cardelli F, Takagi Y, Asturias FJ.

Nat Struct Mol Biol. 2010 Mar;17(3):273-9. doi: 10.1038/nsmb.1757. Epub 2010 Feb 14.

12.

Activator-mediator binding stabilizes RNA polymerase II orientation within the human mediator-RNA polymerase II-TFIIF assembly.

Bernecky C, Taatjes DJ.

J Mol Biol. 2012 Apr 13;417(5):387-94. doi: 10.1016/j.jmb.2012.02.014. Epub 2012 Feb 16.

13.

Interaction of the mediator head module with RNA polymerase II.

Cai G, Chaban YL, Imasaki T, Kovacs JA, Calero G, Penczek PA, Takagi Y, Asturias FJ.

Structure. 2012 May 9;20(5):899-910. doi: 10.1016/j.str.2012.02.023.

14.

Mediator head subcomplex Med11/22 contains a common helix bundle building block with a specific function in transcription initiation complex stabilization.

Seizl M, Larivière L, Pfaffeneder T, Wenzeck L, Cramer P.

Nucleic Acids Res. 2011 Aug;39(14):6291-304. doi: 10.1093/nar/gkr229. Epub 2011 Apr 15.

15.

Mediator phosphorylation prevents stress response transcription during non-stress conditions.

Miller C, Matic I, Maier KC, Schwalb B, Roether S, Strässer K, Tresch A, Mann M, Cramer P.

J Biol Chem. 2012 Dec 28;287(53):44017-26. doi: 10.1074/jbc.M112.430140. Epub 2012 Nov 7.

16.

A conserved Mediator-CDK8 kinase module association regulates Mediator-RNA polymerase II interaction.

Tsai KL, Sato S, Tomomori-Sato C, Conaway RC, Conaway JW, Asturias FJ.

Nat Struct Mol Biol. 2013 May;20(5):611-9. doi: 10.1038/nsmb.2549. Epub 2013 Apr 7.

17.

Model of the Mediator middle module based on protein cross-linking.

Larivière L, Plaschka C, Seizl M, Petrotchenko EV, Wenzeck L, Borchers CH, Cramer P.

Nucleic Acids Res. 2013 Nov;41(20):9266-73. doi: 10.1093/nar/gkt704. Epub 2013 Aug 11.

18.

Structure of transcribing mammalian RNA polymerase II.

Bernecky C, Herzog F, Baumeister W, Plitzko JM, Cramer P.

Nature. 2016 Jan 28;529(7587):551-4. doi: 10.1038/nature16482. Epub 2016 Jan 20.

PMID:
26789250
19.

Redefining the modular organization of the core Mediator complex.

Wang X, Sun Q, Ding Z, Ji J, Wang J, Kong X, Yang J, Cai G.

Cell Res. 2014 Jul;24(7):796-808. doi: 10.1038/cr.2014.64. Epub 2014 May 9.

20.

Mediator recruitment to heat shock genes requires dual Hsf1 activation domains and mediator tail subunits Med15 and Med16.

Kim S, Gross DS.

J Biol Chem. 2013 Apr 26;288(17):12197-213. doi: 10.1074/jbc.M112.449553. Epub 2013 Feb 27.

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