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Items: 1 to 20 of 170

1.

Restriction of advanced glycation end products improves insulin resistance in human type 2 diabetes: potential role of AGER1 and SIRT1.

Uribarri J, Cai W, Ramdas M, Goodman S, Pyzik R, Chen X, Zhu L, Striker GE, Vlassara H.

Diabetes Care. 2011 Jul;34(7):1610-6. doi: 10.2337/dc11-0091.

2.

Oral advanced glycation endproducts (AGEs) promote insulin resistance and diabetes by depleting the antioxidant defenses AGE receptor-1 and sirtuin 1.

Cai W, Ramdas M, Zhu L, Chen X, Striker GE, Vlassara H.

Proc Natl Acad Sci U S A. 2012 Sep 25;109(39):15888-93. Epub 2012 Aug 20.

3.

Suppression of native defense mechanisms, SIRT1 and PPARγ, by dietary glycoxidants precedes disease in adult humans; relevance to lifestyle-engendered chronic diseases.

Uribarri J, Cai W, Pyzik R, Goodman S, Chen X, Zhu L, Ramdas M, Striker GE, Vlassara H.

Amino Acids. 2014 Feb;46(2):301-9. doi: 10.1007/s00726-013-1502-4. Epub 2013 May 1.

4.

Advanced glycation end product receptor-1 transgenic mice are resistant to inflammation, oxidative stress, and post-injury intimal hyperplasia.

Torreggiani M, Liu H, Wu J, Zheng F, Cai W, Striker G, Vlassara H.

Am J Pathol. 2009 Oct;175(4):1722-32. doi: 10.2353/ajpath.2009.090138. Epub 2009 Sep 24.

5.

Reduced oxidant stress and extended lifespan in mice exposed to a low glycotoxin diet: association with increased AGER1 expression.

Cai W, He JC, Zhu L, Chen X, Wallenstein S, Striker GE, Vlassara H.

Am J Pathol. 2007 Jun;170(6):1893-902.

6.

Protection against loss of innate defenses in adulthood by low advanced glycation end products (AGE) intake: role of the antiinflammatory AGE receptor-1.

Vlassara H, Cai W, Goodman S, Pyzik R, Yong A, Chen X, Zhu L, Neade T, Beeri M, Silverman JM, Ferrucci L, Tansman L, Striker GE, Uribarri J.

J Clin Endocrinol Metab. 2009 Nov;94(11):4483-91. doi: 10.1210/jc.2009-0089. Epub 2009 Oct 9.

7.

AGE-receptor-1 counteracts cellular oxidant stress induced by AGEs via negative regulation of p66shc-dependent FKHRL1 phosphorylation.

Cai W, He JC, Zhu L, Chen X, Striker GE, Vlassara H.

Am J Physiol Cell Physiol. 2008 Jan;294(1):C145-52. Epub 2007 Nov 21.

8.

Short-term effects of dietary advanced glycation end products in rats.

Poulsen MW, Andersen JM, Hedegaard RV, Madsen AN, Krath BN, Monošík R, Bak MJ, Nielsen J, Holst B, Skibsted LH, Larsen LH, Dragsted LO.

Br J Nutr. 2016 Feb 28;115(4):629-36. doi: 10.1017/S0007114515004833.

PMID:
26824730
9.

Effects of sevelamer carbonate on advanced glycation end products and antioxidant/pro-oxidant status in patients with diabetic kidney disease.

Yubero-Serrano EM, Woodward M, Poretsky L, Vlassara H, Striker GE; AGE-less Study Group.

Clin J Am Soc Nephrol. 2015 May 7;10(5):759-66. doi: 10.2215/CJN.07750814. Epub 2015 Feb 20.

10.

Oral AGE restriction ameliorates insulin resistance in obese individuals with the metabolic syndrome: a randomised controlled trial.

Vlassara H, Cai W, Tripp E, Pyzik R, Yee K, Goldberg L, Tansman L, Chen X, Mani V, Fayad ZA, Nadkarni GN, Striker GE, He JC, Uribarri J.

Diabetologia. 2016 Oct;59(10):2181-92. doi: 10.1007/s00125-016-4053-x. Epub 2016 Jul 29.

11.

AGER1 regulates endothelial cell NADPH oxidase-dependent oxidant stress via PKC-delta: implications for vascular disease.

Cai W, Torreggiani M, Zhu L, Chen X, He JC, Striker GE, Vlassara H.

Am J Physiol Cell Physiol. 2010 Mar;298(3):C624-34. doi: 10.1152/ajpcell.00463.2009. Epub 2009 Dec 2.

12.

Oral glycotoxins determine the effects of calorie restriction on oxidant stress, age-related diseases, and lifespan.

Cai W, He JC, Zhu L, Chen X, Zheng F, Striker GE, Vlassara H.

Am J Pathol. 2008 Aug;173(2):327-36. doi: 10.2353/ajpath.2008.080152. Epub 2008 Jul 3.

13.

Dietary advanced glycated end-products and medicines influence the expression of SIRT1 and DDOST in peripheral mononuclear cells from long-term type 1 diabetes patients.

Santos-Bezerra DP, Machado-Lima A, Monteiro MB, Admoni SN, Perez RV, Machado CG, Shimizu MH, Cavaleiro AM, Thieme K, Queiroz MS, Machado UF, Giannella-Neto D, Passarelli M, Corrêa-Giannella ML.

Diab Vasc Dis Res. 2018 Jan;15(1):81-89. doi: 10.1177/1479164117733918. Epub 2017 Oct 13.

PMID:
29027826
14.

Inhibition of Advanced Glycation End Products (AGEs) Accumulation by Pyridoxamine Modulates Glomerular and Mesangial Cell Estrogen Receptor α Expression in Aged Female Mice.

Pereira-Simon S, Rubio GA, Xia X, Cai W, Choi R, Striker GE, Elliot SJ.

PLoS One. 2016 Jul 18;11(7):e0159666. doi: 10.1371/journal.pone.0159666. eCollection 2016.

15.

Elevated serum advanced glycation endproducts in obese indicate risk for the metabolic syndrome: a link between healthy and unhealthy obesity?

Uribarri J, Cai W, Woodward M, Tripp E, Goldberg L, Pyzik R, Yee K, Tansman L, Chen X, Mani V, Fayad ZA, Vlassara H.

J Clin Endocrinol Metab. 2015 May;100(5):1957-66. doi: 10.1210/jc.2014-3925. Epub 2015 Feb 19.

16.

Polydatin promotes Nrf2-ARE anti-oxidative pathway through activating Sirt1 to resist AGEs-induced upregulation of fibronetin and transforming growth factor-β1 in rat glomerular messangial cells.

Huang K, Chen C, Hao J, Huang J, Wang S, Liu P, Huang H.

Mol Cell Endocrinol. 2015 Jan 5;399:178-89. doi: 10.1016/j.mce.2014.08.014. Epub 2014 Sep 2.

PMID:
25192797
17.

Serum advanced glycation end products (AGEs) are associated with insulin resistance.

Tan KC, Shiu SW, Wong Y, Tam X.

Diabetes Metab Res Rev. 2011 Jul;27(5):488-92. doi: 10.1002/dmrr.1188.

PMID:
21337488
18.

Advanced glycation endproducts in food and their effects on health.

Poulsen MW, Hedegaard RV, Andersen JM, de Courten B, Bügel S, Nielsen J, Skibsted LH, Dragsted LO.

Food Chem Toxicol. 2013 Oct;60:10-37. doi: 10.1016/j.fct.2013.06.052. Epub 2013 Jul 16. Review.

PMID:
23867544
19.

AGE restriction in diabetes mellitus: a paradigm shift.

Vlassara H, Striker GE.

Nat Rev Endocrinol. 2011 May 24;7(9):526-39. doi: 10.1038/nrendo.2011.74. Review.

20.

Sirt1 resists advanced glycation end products-induced expressions of fibronectin and TGF-β1 by activating the Nrf2/ARE pathway in glomerular mesangial cells.

Huang K, Huang J, Xie X, Wang S, Chen C, Shen X, Liu P, Huang H.

Free Radic Biol Med. 2013 Dec;65:528-40. doi: 10.1016/j.freeradbiomed.2013.07.029. Epub 2013 Jul 24.

PMID:
23891678

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