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Items: 1 to 20 of 83

1.

Regulation of NF-κB activity by competition between RelA acetylation and ubiquitination.

Li H, Wittwer T, Weber A, Schneider H, Moreno R, Maine GN, Kracht M, Schmitz ML, Burstein E.

Oncogene. 2012 Feb 2;31(5):611-23. doi: 10.1038/onc.2011.253. Epub 2011 Jun 27.

2.

Tumor necrosis factor-alpha induces RelA degradation via ubiquitination at lysine 195 to prevent excessive nuclear factor-kappaB activation.

Fan Y, Mao R, Zhao Y, Yu Y, Sun W, Song P, Shi Z, Zhang D, Yvon E, Zhang H, Fu S, Yang J.

J Biol Chem. 2009 Oct 23;284(43):29290-7. doi: 10.1074/jbc.M109.018994. Epub 2009 Aug 25.

3.

NF-kappaB RelA phosphorylation regulates RelA acetylation.

Chen LF, Williams SA, Mu Y, Nakano H, Duerr JM, Buckbinder L, Greene WC.

Mol Cell Biol. 2005 Sep;25(18):7966-75.

4.

Monoubiquitination of nuclear RelA negatively regulates NF-κB activity independent of proteasomal degradation.

Hochrainer K, Racchumi G, Zhang S, Iadecola C, Anrather J.

Cell Mol Life Sci. 2012 Jun;69(12):2057-73. doi: 10.1007/s00018-011-0912-2. Epub 2012 Jan 20.

5.

Functional interplay between acetylation and methylation of the RelA subunit of NF-kappaB.

Yang XD, Tajkhorshid E, Chen LF.

Mol Cell Biol. 2010 May;30(9):2170-80. doi: 10.1128/MCB.01343-09. Epub 2010 Feb 16.

6.

Modification of RelA by O-linked N-acetylglucosamine links glucose metabolism to NF-κB acetylation and transcription.

Allison DF, Wamsley JJ, Kumar M, Li D, Gray LG, Hart GW, Jones DR, Mayo MW.

Proc Natl Acad Sci U S A. 2012 Oct 16;109(42):16888-93. doi: 10.1073/pnas.1208468109. Epub 2012 Oct 1.

7.

p28(GANK) associates with p300 to attenuate the acetylation of RelA.

Ren YB, Luo T, Li J, Fu J, Wang Q, Cao GW, Chen Y, Wang HY.

Mol Carcinog. 2015 Dec;54(12):1626-35. doi: 10.1002/mc.22235. Epub 2014 Nov 14.

PMID:
25400040
8.

CSN-associated USP48 confers stability to nuclear NF-κB/RelA by trimming K48-linked Ub-chains.

Schweitzer K, Naumann M.

Biochim Biophys Acta. 2015 Feb;1853(2):453-69. doi: 10.1016/j.bbamcr.2014.11.028. Epub 2014 Dec 5.

9.

Methodology to study NF-κB/RelA ubiquitination in vivo.

Li H, Starokadomskyy P, Burstein E.

Methods Mol Biol. 2015;1280:371-81. doi: 10.1007/978-1-4939-2422-6_22.

PMID:
25736761
10.
11.

The ubiquitin ligase HERC3 attenuates NF-κB-dependent transcription independently of its enzymatic activity by delivering the RelA subunit for degradation.

Hochrainer K, Pejanovic N, Olaseun VA, Zhang S, Iadecola C, Anrather J.

Nucleic Acids Res. 2015 Nov 16;43(20):9889-904. doi: 10.1093/nar/gkv1064. Epub 2015 Oct 17.

12.

Thr435 phosphorylation regulates RelA (p65) NF-kappaB subunit transactivation.

O'Shea JM, Perkins ND.

Biochem J. 2010 Feb 24;426(3):345-54. doi: 10.1042/BJ20091630.

13.

Methods to detect NF-κB acetylation and methylation.

Chen J, Chen LF.

Methods Mol Biol. 2015;1280:395-409. doi: 10.1007/978-1-4939-2422-6_24.

14.

1B/(-)IRE DMT1 expression during brain ischemia contributes to cell death mediated by NF-κB/RelA acetylation at Lys310.

Ingrassia R, Lanzillotta A, Sarnico I, Benarese M, Blasi F, Borgese L, Bilo F, Depero L, Chiarugi A, Spano PF, Pizzi M.

PLoS One. 2012;7(5):e38019. doi: 10.1371/journal.pone.0038019. Epub 2012 May 29.

15.

Exclusive ubiquitination and sumoylation on overlapping lysine residues mediate NF-kappaB activation by the human T-cell leukemia virus tax oncoprotein.

Lamsoul I, Lodewick J, Lebrun S, Brasseur R, Burny A, Gaynor RB, Bex F.

Mol Cell Biol. 2005 Dec;25(23):10391-406.

16.

CD28 costimulation regulates FOXP3 in a RelA/NF-κB-dependent mechanism.

Soligo M, Camperio C, Caristi S, Scottà C, Del Porto P, Costanzo A, Mantel PY, Schmidt-Weber CB, Piccolella E.

Eur J Immunol. 2011 Feb;41(2):503-13. doi: 10.1002/eji.201040712. Epub 2011 Jan 11.

17.

Brd4 maintains constitutively active NF-κB in cancer cells by binding to acetylated RelA.

Zou Z, Huang B, Wu X, Zhang H, Qi J, Bradner J, Nair S, Chen LF.

Oncogene. 2014 May 1;33(18):2395-404. doi: 10.1038/onc.2013.179. Epub 2013 May 20.

18.

Role of Ca2+/calmodulin-dependent kinase II-IRAK1 interaction in LMP1-induced NF-κB activation.

Kim JE, Kim SY, Lim SY, Kieff E, Song YJ.

Mol Cell Biol. 2014 Feb;34(3):325-34. doi: 10.1128/MCB.00912-13. Epub 2013 Nov 18.

19.

Brd4 coactivates transcriptional activation of NF-kappaB via specific binding to acetylated RelA.

Huang B, Yang XD, Zhou MM, Ozato K, Chen LF.

Mol Cell Biol. 2009 Mar;29(5):1375-87. doi: 10.1128/MCB.01365-08. Epub 2008 Dec 22.

20.

Regulation of NF-kappaB action by reversible acetylation.

Greene WC, Chen LF.

Novartis Found Symp. 2004;259:208-17; discussion 218-25. Review.

PMID:
15171256

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