Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 112

1.

NLRX1 negatively regulates TLR-induced NF-κB signaling by targeting TRAF6 and IKK.

Xia X, Cui J, Wang HY, Zhu L, Matsueda S, Wang Q, Yang X, Hong J, Songyang Z, Chen ZJ, Wang RF.

Immunity. 2011 Jun 24;34(6):843-53. doi: 10.1016/j.immuni.2011.02.022.

2.

USP18 negatively regulates NF-κB signaling by targeting TAK1 and NEMO for deubiquitination through distinct mechanisms.

Yang Z, Xian H, Hu J, Tian S, Qin Y, Wang RF, Cui J.

Sci Rep. 2015 Aug 4;5:12738. doi: 10.1038/srep12738.

3.

Quercetin disrupts tyrosine-phosphorylated phosphatidylinositol 3-kinase and myeloid differentiation factor-88 association, and inhibits MAPK/AP-1 and IKK/NF-κB-induced inflammatory mediators production in RAW 264.7 cells.

Endale M, Park SC, Kim S, Kim SH, Yang Y, Cho JY, Rhee MH.

Immunobiology. 2013 Dec;218(12):1452-67. doi: 10.1016/j.imbio.2013.04.019. Epub 2013 May 9.

PMID:
23735482
4.

The innate immune sensor NLRC3 attenuates Toll-like receptor signaling via modification of the signaling adaptor TRAF6 and transcription factor NF-κB.

Schneider M, Zimmermann AG, Roberts RA, Zhang L, Swanson KV, Wen H, Davis BK, Allen IC, Holl EK, Ye Z, Rahman AH, Conti BJ, Eitas TK, Koller BH, Ting JP.

Nat Immunol. 2012 Sep;13(9):823-31. doi: 10.1038/ni.2378. Epub 2012 Aug 5.

5.

NLRX1 protein attenuates inflammatory responses to infection by interfering with the RIG-I-MAVS and TRAF6-NF-κB signaling pathways.

Allen IC, Moore CB, Schneider M, Lei Y, Davis BK, Scull MA, Gris D, Roney KE, Zimmermann AG, Bowzard JB, Ranjan P, Monroe KM, Pickles RJ, Sambhara S, Ting JP.

Immunity. 2011 Jun 24;34(6):854-65. doi: 10.1016/j.immuni.2011.03.026.

6.

TRAF6-dependent Act1 phosphorylation by the IκB kinase-related kinases suppresses interleukin-17-induced NF-κB activation.

Qu F, Gao H, Zhu S, Shi P, Zhang Y, Liu Y, Jallal B, Yao Y, Shi Y, Qian Y.

Mol Cell Biol. 2012 Oct;32(19):3925-37. doi: 10.1128/MCB.00268-12. Epub 2012 Jul 30.

7.

TRAF Family Member-associated NF-κB Activator (TANK) Inhibits Genotoxic Nuclear Factor κB Activation by Facilitating Deubiquitinase USP10-dependent Deubiquitination of TRAF6 Ligase.

Wang W, Huang X, Xin HB, Fu M, Xue A, Wu ZH.

J Biol Chem. 2015 May 22;290(21):13372-85. doi: 10.1074/jbc.M115.643767. Epub 2015 Apr 10.

8.

Regulation and function of IKK and IKK-related kinases.

Häcker H, Karin M.

Sci STKE. 2006 Oct 17;2006(357):re13. Review.

PMID:
17047224
9.

Site-specific Lys-63-linked tumor necrosis factor receptor-associated factor 6 auto-ubiquitination is a critical determinant of I kappa B kinase activation.

Lamothe B, Besse A, Campos AD, Webster WK, Wu H, Darnay BG.

J Biol Chem. 2007 Feb 9;282(6):4102-12. Epub 2006 Nov 29.

10.

HSP27 regulates IL-1 stimulated IKK activation through interacting with TRAF6 and affecting its ubiquitination.

Wu Y, Liu J, Zhang Z, Huang H, Shen J, Zhang S, Jiang Y, Luo L, Yin Z.

Cell Signal. 2009 Jan;21(1):143-50. doi: 10.1016/j.cellsig.2008.10.001. Epub 2008 Oct 10.

PMID:
18950704
11.

LRRC14 attenuates Toll-like receptor-mediated NF-κB signaling through disruption of IKK complex.

Wu C, Yang Y, Ou J, Zhu L, Zhao W, Cui J.

Exp Cell Res. 2016 Sep 10;347(1):65-73. doi: 10.1016/j.yexcr.2016.07.011. Epub 2016 Jul 15.

PMID:
27426725
12.

BAT3 negatively regulates lipopolysaccharide-induced NF-κB signaling through TRAF6.

Lee Y, Lee IY, Yun HJ, Lee WS, Kang S, Cho SG, Lee JE, Choi EJ.

Biochem Biophys Res Commun. 2016 Sep 16;478(2):784-90. doi: 10.1016/j.bbrc.2016.08.025. Epub 2016 Aug 5.

PMID:
27501752
13.

Lys63-linked polyubiquitination of IRAK-1 is required for interleukin-1 receptor- and toll-like receptor-mediated NF-kappaB activation.

Conze DB, Wu CJ, Thomas JA, Landstrom A, Ashwell JD.

Mol Cell Biol. 2008 May;28(10):3538-47. doi: 10.1128/MCB.02098-07. Epub 2008 Mar 17.

14.

TRAF6 negatively regulates TNFalpha-induced NF-kappaB activation.

Funakoshi-Tago M, Kamada N, Shimizu T, Hashiguchi Y, Tago K, Sonoda Y, Kasahara T.

Cytokine. 2009 Feb;45(2):72-9. doi: 10.1016/j.cyto.2008.10.010. Epub 2008 Dec 16.

PMID:
19091594
15.

TRAF6 establishes innate immune responses by activating NF-kappaB and IRF7 upon sensing cytosolic viral RNA and DNA.

Konno H, Yamamoto T, Yamazaki K, Gohda J, Akiyama T, Semba K, Goto H, Kato A, Yujiri T, Imai T, Kawaguchi Y, Su B, Takeuchi O, Akira S, Tsunetsugu-Yokota Y, Inoue J.

PLoS One. 2009 May 25;4(5):e5674. doi: 10.1371/journal.pone.0005674.

16.

Phosphoinositide-dependent kinase-1 inhibits TRAF6 ubiquitination by interrupting the formation of TAK1-TAB2 complex in TLR4 signaling.

Moon G, Kim J, Min Y, Wi SM, Shim JH, Chun E, Lee KY.

Cell Signal. 2015 Dec;27(12):2524-33. doi: 10.1016/j.cellsig.2015.09.018. Epub 2015 Sep 30.

PMID:
26432169
17.

MyD88 adapter-like (Mal)/TIRAP interaction with TRAF6 is critical for TLR2- and TLR4-mediated NF-kappaB proinflammatory responses.

Verstak B, Nagpal K, Bottomley SP, Golenbock DT, Hertzog PJ, Mansell A.

J Biol Chem. 2009 Sep 4;284(36):24192-203. doi: 10.1074/jbc.M109.023044. Epub 2009 Jul 10.

18.

Pattern recognition scavenger receptor CD204 attenuates Toll-like receptor 4-induced NF-kappaB activation by directly inhibiting ubiquitination of tumor necrosis factor (TNF) receptor-associated factor 6.

Yu X, Yi H, Guo C, Zuo D, Wang Y, Kim HL, Subjeck JR, Wang XY.

J Biol Chem. 2011 May 27;286(21):18795-806. doi: 10.1074/jbc.M111.224345. Epub 2011 Apr 1.

19.

hCINAP negatively regulates NF-κB signaling by recruiting the phosphatase PP1 to deactivate IKK complex.

Qu L, Ji Y, Zhu X, Zheng X.

J Mol Cell Biol. 2015 Dec;7(6):529-42. doi: 10.1093/jmcb/mjv041. Epub 2015 Jun 18.

PMID:
26089539
20.

Interleukin-1-induced NF-kappaB activation is NEMO-dependent but does not require IKKbeta.

Solt LA, Madge LA, Orange JS, May MJ.

J Biol Chem. 2007 Mar 23;282(12):8724-33. Epub 2007 Jan 23.

Supplemental Content

Support Center