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Reference ranges for testosterone in men generated using liquid chromatography tandem mass spectrometry in a community-based sample of healthy nonobese young men in the Framingham Heart Study and applied to three geographically distinct cohorts.

Bhasin S, Pencina M, Jasuja GK, Travison TG, Coviello A, Orwoll E, Wang PY, Nielson C, Wu F, Tajar A, Labrie F, Vesper H, Zhang A, Ulloor J, Singh R, D'Agostino R, Vasan RS.

J Clin Endocrinol Metab. 2011 Aug;96(8):2430-9. doi: 10.1210/jc.2010-3012. Epub 2011 Jun 22.


Age-specific reference ranges for serum testosterone and androstenedione concentrations in women measured by liquid chromatography-tandem mass spectrometry.

Haring R, Hannemann A, John U, Radke D, Nauck M, Wallaschofski H, Owen L, Adaway J, Keevil BG, Brabant G.

J Clin Endocrinol Metab. 2012 Feb;97(2):408-15. doi: 10.1210/jc.2011-2134. Epub 2011 Dec 7.


Harmonized Reference Ranges for Circulating Testosterone Levels in Men of Four Cohort Studies in the United States and Europe.

Travison TG, Vesper HW, Orwoll E, Wu F, Kaufman JM, Wang Y, Lapauw B, Fiers T, Matsumoto AM, Bhasin S.

J Clin Endocrinol Metab. 2017 Apr 1;102(4):1161-1173. doi: 10.1210/jc.2016-2935.


The prevalence of and risk factors for androgen deficiency in aging Taiwanese men.

Liu CC, Wu WJ, Lee YC, Wang CJ, Ke HL, Li WM, Hsiao HL, Yeh HC, Li CC, Chou YH, Huang CH, Huang SP.

J Sex Med. 2009 Apr;6(4):936-46. doi: 10.1111/j.1743-6109.2008.01171.x. Epub 2008 Feb 9.


Reference ranges and determinants of testosterone, dihydrotestosterone, and estradiol levels measured using liquid chromatography-tandem mass spectrometry in a population-based cohort of older men.

Yeap BB, Alfonso H, Chubb SA, Handelsman DJ, Hankey GJ, Norman PE, Flicker L.

J Clin Endocrinol Metab. 2012 Nov;97(11):4030-9. doi: 10.1210/jc.2012-2265. Epub 2012 Sep 13.


Free testosterone levels are associated with mobility limitation and physical performance in community-dwelling men: the Framingham Offspring Study.

Krasnoff JB, Basaria S, Pencina MJ, Jasuja GK, Vasan RS, Ulloor J, Zhang A, Coviello A, Kelly-Hayes M, D'Agostino RB, Wolf PA, Bhasin S, Murabito JM.

J Clin Endocrinol Metab. 2010 Jun;95(6):2790-9. doi: 10.1210/jc.2009-2680. Epub 2010 Apr 9.


Low circulating levels of insulin-like growth factors and testosterone in chronically institutionalized elderly men.

Abbasi AA, Drinka PJ, Mattson DE, Rudman D.

J Am Geriatr Soc. 1993 Sep;41(9):975-82.


Specificity and predictive value of circulating testosterone assessed by tandem mass spectrometry for the diagnosis of polycystic ovary syndrome by the National Institutes of Health 1990 criteria.

Salameh WA, Redor-Goldman MM, Clarke NJ, Mathur R, Azziz R, Reitz RE.

Fertil Steril. 2014 Apr;101(4):1135-1141.e2. doi: 10.1016/j.fertnstert.2013.12.056. Epub 2014 Feb 15. Erratum in: Fertil Steril. 2015 Jan;103(1):299.


Comparison of testosterone fractions between Framingham Heart Study participants and Japanese participants.

Taya M, Koh E, Izumi K, Iijima M, Maeda Y, Matsushita T, Iwamoto T, Namiki M.

Int J Urol. 2014 Jul;21(7):689-95. doi: 10.1111/iju.12393. Epub 2014 Jan 9.


The determination of total testosterone and free testosterone (RIA) are not applicable to the evaluation of gonadal function in HIV-infected males.

Moreno-Pérez O, Escoín C, Serna-Candel C, Portilla J, Boix V, Alfayate R, González-Sánchez V, Mauri M, Sánchez-Payá J, Picó A.

J Sex Med. 2010 Aug;7(8):2873-83. doi: 10.1111/j.1743-6109.2010.01886.x. Epub 2010 Jul 7.


Association of Free Testosterone With Hypogonadal Symptoms in Men With Near-normal Total Testosterone Levels.

Ramasamy R, Golan R, Wilken N, Scovell JM, Lipshultz LI.

Urology. 2015 Aug;86(2):287-90. doi: 10.1016/j.urology.2015.05.007. Epub 2015 Jul 18.


Current Practices of Measuring and Reference Range Reporting of Free and Total Testosterone in the United States.

Le M, Flores D, May D, Gourley E, Nangia AK.

J Urol. 2016 May;195(5):1556-61. doi: 10.1016/j.juro.2015.12.070. Epub 2015 Dec 18.


Age trends in estradiol and estrone levels measured using liquid chromatography tandem mass spectrometry in community-dwelling men of the Framingham Heart Study.

Jasuja GK, Travison TG, Davda M, Murabito JM, Basaria S, Zhang A, Kushnir MM, Rockwood AL, Meikle W, Pencina MJ, Coviello A, Rose AJ, D'Agostino R, Vasan RS, Bhasin S.

J Gerontol A Biol Sci Med Sci. 2013 Jun;68(6):733-40. doi: 10.1093/gerona/gls216. Epub 2012 Oct 25.


Low Free Testosterone Is Associated with Hypogonadal Signs and Symptoms in Men with Normal Total Testosterone.

Antonio L, Wu FC, O'Neill TW, Pye SR, Ahern TB, Laurent MR, Huhtaniemi IT, Lean ME, Keevil BG, Rastrelli G, Forti G, Bartfai G, Casanueva FF, Kula K, Punab M, Giwercman A, Claessens F, Decallonne B, Vanderschueren D; European Male Ageing Study Study Group.

J Clin Endocrinol Metab. 2016 Jul;101(7):2647-57. doi: 10.1210/jc.2015-4106. Epub 2016 Feb 24.


Subjective sexual response to testosterone replacement therapy based on initial serum levels of total testosterone.

Reyes-Vallejo L, Lazarou S, Morgentaler A.

J Sex Med. 2007 Nov;4(6):1757-62. Epub 2006 Nov 6.


[Evaluation of relationships between plasma androgens level and clinical signs of hipoandrogenism according to age and comorbidity of metabolic syndrome in men].

Herman WA, Krzoska A, Pawliczak E, Roszak M, Łacka K.

Pol Merkur Lekarski. 2014 Jan;36(211):16-21. Polish.


Adult testosterone and calculated free testosterone reference ranges by tandem mass spectrometry.

Neale SM, Hocking R, Biswas M, Turkes A, Rees D, Rees DA, Evans C.

Ann Clin Biochem. 2013 Mar;50(Pt 2):159-61. doi: 10.1258/acb.2012.012047. Epub 2013 Feb 12.


The heritability of circulating testosterone, oestradiol, oestrone and sex hormone binding globulin concentrations in men: the Framingham Heart Study.

Travison TG, Zhuang WV, Lunetta KL, Karasik D, Bhasin S, Kiel DP, Coviello AD, Murabito JM.

Clin Endocrinol (Oxf). 2014 Feb;80(2):277-82. doi: 10.1111/cen.12260. Epub 2013 Jun 27.


Morning free and total testosterone in HIV-infected men: implications for the assessment of hypogonadism.

Monroe AK, Dobs AS, Palella FJ, Kingsley LA, Witt MD, Brown TT.

AIDS Res Ther. 2014 Jan 22;11(1):6. doi: 10.1186/1742-6405-11-6.

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