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Items: 1 to 20 of 297

1.

Preconditioning involves selective mitophagy mediated by Parkin and p62/SQSTM1.

Huang C, Andres AM, Ratliff EP, Hernandez G, Lee P, Gottlieb RA.

PLoS One. 2011;6(6):e20975. doi: 10.1371/journal.pone.0020975. Epub 2011 Jun 8.

2.

p62/SQSTM1 is required for Parkin-induced mitochondrial clustering but not mitophagy; VDAC1 is dispensable for both.

Narendra D, Kane LA, Hauser DN, Fearnley IM, Youle RJ.

Autophagy. 2010 Nov;6(8):1090-106.

3.

Nix is critical to two distinct phases of mitophagy, reactive oxygen species-mediated autophagy induction and Parkin-ubiquitin-p62-mediated mitochondrial priming.

Ding WX, Ni HM, Li M, Liao Y, Chen X, Stolz DB, Dorn GW 2nd, Yin XM.

J Biol Chem. 2010 Sep 3;285(36):27879-90. doi: 10.1074/jbc.M110.119537. Epub 2010 Jun 23.

4.

Mitophagy is required for acute cardioprotection by simvastatin.

Andres AM, Hernandez G, Lee P, Huang C, Ratliff EP, Sin J, Thornton CA, Damasco MV, Gottlieb RA.

Antioxid Redox Signal. 2014 Nov 10;21(14):1960-73. doi: 10.1089/ars.2013.5416. Epub 2013 Sep 20.

5.

Parkin-induced ubiquitination of Mff promotes its association with p62/SQSTM1 during mitochondrial depolarization.

Gao J, Qin S, Jiang C.

Acta Biochim Biophys Sin (Shanghai). 2015 Jul;47(7):522-9. doi: 10.1093/abbs/gmv044. Epub 2015 May 24.

PMID:
26008206
6.

AMBRA1 is able to induce mitophagy via LC3 binding, regardless of PARKIN and p62/SQSTM1.

Strappazzon F, Nazio F, Corrado M, Cianfanelli V, Romagnoli A, Fimia GM, Campello S, Nardacci R, Piacentini M, Campanella M, Cecconi F.

Cell Death Differ. 2015 Mar;22(3):419-32. doi: 10.1038/cdd.2014.139. Epub 2014 Sep 12. Erratum in: Cell Death Differ. 2015 Mar;22(3):517.

7.

Optineurin is an autophagy receptor for damaged mitochondria in parkin-mediated mitophagy that is disrupted by an ALS-linked mutation.

Wong YC, Holzbaur EL.

Proc Natl Acad Sci U S A. 2014 Oct 21;111(42):E4439-48. doi: 10.1073/pnas.1405752111. Epub 2014 Oct 7.

8.

PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1.

Geisler S, Holmström KM, Skujat D, Fiesel FC, Rothfuss OC, Kahle PJ, Springer W.

Nat Cell Biol. 2010 Feb;12(2):119-31. doi: 10.1038/ncb2012. Epub 2010 Jan 24.

PMID:
20098416
9.

Mitochondrial and lysosomal biogenesis are activated following PINK1/parkin-mediated mitophagy.

Ivankovic D, Chau KY, Schapira AH, Gegg ME.

J Neurochem. 2016 Jan;136(2):388-402. doi: 10.1111/jnc.13412. Epub 2015 Nov 24.

10.

TBK1 controls autophagosomal engulfment of polyubiquitinated mitochondria through p62/SQSTM1 phosphorylation.

Matsumoto G, Shimogori T, Hattori N, Nukina N.

Hum Mol Genet. 2015 Aug 1;24(15):4429-42. doi: 10.1093/hmg/ddv179. Epub 2015 May 13.

PMID:
25972374
11.

Interdependence of Parkin-Mediated Mitophagy and Mitochondrial Fission in Adult Mouse Hearts.

Song M, Gong G, Burelle Y, Gustafsson ÅB, Kitsis RN, Matkovich SJ, Dorn GW 2nd.

Circ Res. 2015 Jul 31;117(4):346-51. doi: 10.1161/CIRCRESAHA.117.306859. Epub 2015 Jun 2.

12.

Tumor necrosis factor receptor-associated factor 2 mediates mitochondrial autophagy.

Yang KC, Ma X, Liu H, Murphy J, Barger PM, Mann DL, Diwan A.

Circ Heart Fail. 2015 Jan;8(1):175-87. doi: 10.1161/CIRCHEARTFAILURE.114.001635. Epub 2014 Oct 22.

13.

Acetylcholine Attenuates Hypoxia/Reoxygenation Injury by Inducing Mitophagy Through PINK1/Parkin Signal Pathway in H9c2 Cells.

Sun L, Zhao M, Yang Y, Xue RQ, Yu XJ, Liu JK, Zang WJ.

J Cell Physiol. 2016 May;231(5):1171-81. doi: 10.1002/jcp.25215. Epub 2015 Oct 23.

PMID:
26465230
14.

PMI: a ΔΨm independent pharmacological regulator of mitophagy.

East DA, Fagiani F, Crosby J, Georgakopoulos ND, Bertrand H, Schaap M, Fowkes A, Wells G, Campanella M.

Chem Biol. 2014 Nov 20;21(11):1585-96. doi: 10.1016/j.chembiol.2014.09.019.

15.

WDR26 promotes mitophagy of cardiomyocytes induced by hypoxia through Parkin translocation.

Feng Y, Zhao J, Hou H, Zhang H, Jiao Y, Wang J, Wang Y, Sun Y.

Acta Biochim Biophys Sin (Shanghai). 2016 Dec;48(12):1075-1084. Epub 2016 Oct 19.

PMID:
27797717
16.

p62/SQSTM1 cooperates with Parkin for perinuclear clustering of depolarized mitochondria.

Okatsu K, Saisho K, Shimanuki M, Nakada K, Shitara H, Sou YS, Kimura M, Sato S, Hattori N, Komatsu M, Tanaka K, Matsuda N.

Genes Cells. 2010 Aug;15(8):887-900. doi: 10.1111/j.1365-2443.2010.01426.x. Epub 2010 Jul 2.

17.

Choline dehydrogenase interacts with SQSTM1/p62 to recruit LC3 and stimulate mitophagy.

Park S, Choi SG, Yoo SM, Son JH, Jung YK.

Autophagy. 2014;10(11):1906-20. doi: 10.4161/auto.32177. Epub 2014 Oct 30.

18.

Parkin promotes proteasomal degradation of p62: implication of selective vulnerability of neuronal cells in the pathogenesis of Parkinson's disease.

Song P, Li S, Wu H, Gao R, Rao G, Wang D, Chen Z, Ma B, Wang H, Sui N, Deng H, Zhang Z, Tang T, Tan Z, Han Z, Lu T, Zhu Y, Chen Q.

Protein Cell. 2016 Feb;7(2):114-29. doi: 10.1007/s13238-015-0230-9. Epub 2016 Jan 8.

19.

Hepatitis C virus core protein suppresses mitophagy by interacting with parkin in the context of mitochondrial depolarization.

Hara Y, Yanatori I, Ikeda M, Kiyokage E, Nishina S, Tomiyama Y, Toida K, Kishi F, Kato N, Imamura M, Chayama K, Hino K.

Am J Pathol. 2014 Nov;184(11):3026-39. doi: 10.1016/j.ajpath.2014.07.024. Epub 2014 Sep 20.

PMID:
25244949
20.

Activation of the ubiquitin-proteasome system against arsenic trioxide cardiotoxicity involves ubiquitin ligase Parkin for mitochondrial homeostasis.

Watanabe M, Funakoshi T, Unuma K, Aki T, Uemura K.

Toxicology. 2014 Aug 1;322:43-50. doi: 10.1016/j.tox.2014.04.008. Epub 2014 May 4.

PMID:
24801902

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