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Items: 1 to 20 of 93

1.

Inositol hexakisphosphate kinase 1 regulates neutrophil function in innate immunity by inhibiting phosphatidylinositol-(3,4,5)-trisphosphate signaling.

Prasad A, Jia Y, Chakraborty A, Li Y, Jain SK, Zhong J, Roy SG, Loison F, Mondal S, Sakai J, Blanchard C, Snyder SH, Luo HR.

Nat Immunol. 2011 Jun 19;12(8):752-60. doi: 10.1038/ni.2052.

2.

Cigarette smoke (CS) and nicotine delay neutrophil spontaneous death via suppressing production of diphosphoinositol pentakisphosphate.

Xu Y, Li H, Bajrami B, Kwak H, Cao S, Liu P, Zhou J, Zhou Y, Zhu H, Ye K, Luo HR.

Proc Natl Acad Sci U S A. 2013 May 7;110(19):7726-31. doi: 10.1073/pnas.1302906110. Epub 2013 Apr 22.

3.

Inositol pyrophosphates mediate chemotaxis in Dictyostelium via pleckstrin homology domain-PtdIns(3,4,5)P3 interactions.

Luo HR, Huang YE, Chen JC, Saiardi A, Iijima M, Ye K, Huang Y, Nagata E, Devreotes P, Snyder SH.

Cell. 2003 Sep 5;114(5):559-72.

4.

Inositol 1,3,4,5-tetrakisphosphate negatively regulates phosphatidylinositol-3,4,5- trisphosphate signaling in neutrophils.

Jia Y, Subramanian KK, Erneux C, Pouillon V, Hattori H, Jo H, You J, Zhu D, Schurmans S, Luo HR.

Immunity. 2007 Sep;27(3):453-67. Epub 2007 Sep 6.

5.

Regulation of phosphatidylinositol 3-kinase activity and phosphatidylinositol 3,4,5-trisphosphate accumulation by neutrophil priming agents.

Cadwallader KA, Condliffe AM, McGregor A, Walker TR, White JF, Stephens LR, Chilvers ER.

J Immunol. 2002 Sep 15;169(6):3336-44.

6.

PPIP5K1 modulates ligand competition between diphosphoinositol polyphosphates and PtdIns(3,4,5)P3 for polyphosphoinositide-binding domains.

Gokhale NA, Zaremba A, Janoshazi AK, Weaver JD, Shears SB.

Biochem J. 2013 Aug 1;453(3):413-26. doi: 10.1042/BJ20121528.

7.

Inositol hexakisphosphate kinase-2, a physiologic mediator of cell death.

Nagata E, Luo HR, Saiardi A, Bae BI, Suzuki N, Snyder SH.

J Biol Chem. 2005 Jan 14;280(2):1634-40. Epub 2004 Nov 8.

8.

When worlds collide: inositol pyrophosphates and phosphoinositides intersect at the plasma membrane.

Erneux C, Elong Edimo W.

Biochem J. 2013 Aug 1;453(3):e3-4. doi: 10.1042/BJ20130785.

PMID:
23849059
9.

The Significance of the Bifunctional Kinase/Phosphatase Activities of Diphosphoinositol Pentakisphosphate Kinases (PPIP5Ks) for Coupling Inositol Pyrophosphate Cell Signaling to Cellular Phosphate Homeostasis.

Gu C, Nguyen HN, Hofer A, Jessen HJ, Dai X, Wang H, Shears SB.

J Biol Chem. 2017 Mar 17;292(11):4544-4555. doi: 10.1074/jbc.M116.765743. Epub 2017 Jan 26.

PMID:
28126903
10.

Molecular control of PtdIns(3,4,5)P3 signaling in neutrophils.

Luo HR, Mondal S.

EMBO Rep. 2015 Feb;16(2):149-63. doi: 10.15252/embr.201439466. Epub 2015 Jan 9. Review.

11.

The enzymes of human diphosphoinositol polyphosphate metabolism.

Thomas MP, Potter BV.

FEBS J. 2014 Jan;281(1):14-33. doi: 10.1111/febs.12575. Epub 2013 Nov 5. Review.

12.

Focal adhesion kinase regulates pathogen-killing capability and life span of neutrophils via mediating both adhesion-dependent and -independent cellular signals.

Kasorn A, Alcaide P, Jia Y, Subramanian KK, Sarraj B, Li Y, Loison F, Hattori H, Silberstein LE, Luscinskas WF, Luo HR.

J Immunol. 2009 Jul 15;183(2):1032-43. doi: 10.4049/jimmunol.0802984. Epub 2009 Jun 26.

14.

Cloning and characterization of two human VIP1-like inositol hexakisphosphate and diphosphoinositol pentakisphosphate kinases.

Fridy PC, Otto JC, Dollins DE, York JD.

J Biol Chem. 2007 Oct 19;282(42):30754-62. Epub 2007 Aug 9.

15.

Two inositol hexakisphosphate kinases drive inositol pyrophosphate synthesis in plants.

Desai M, Rangarajan P, Donahue JL, Williams SP, Land ES, Mandal MK, Phillippy BQ, Perera IY, Raboy V, Gillaspy GE.

Plant J. 2014 Nov;80(4):642-53. doi: 10.1111/tpj.12669.

16.

Regulation of innate immunity by inositol 1,3,4,5-tetrakisphosphate.

Jia Y, Schurmans S, Luo HR.

Cell Cycle. 2008 Sep 15;7(18):2803-8. Epub 2008 Sep 28.

PMID:
18769148
17.

Secretagogue-induced phosphoinositide metabolism in human leucocytes.

Dougherty RW, Godfrey PP, Hoyle PC, Putney JW Jr, Freer RJ.

Biochem J. 1984 Sep 1;222(2):307-14.

18.

Rac and Cdc42 play distinct roles in regulating PI(3,4,5)P3 and polarity during neutrophil chemotaxis.

Srinivasan S, Wang F, Glavas S, Ott A, Hofmann F, Aktories K, Kalman D, Bourne HR.

J Cell Biol. 2003 Feb 3;160(3):375-85. Epub 2003 Jan 27.

19.

Deletion of inositol hexakisphosphate kinase 1 (IP6K1) reduces cell migration and invasion, conferring protection from aerodigestive tract carcinoma in mice.

Jadav RS, Kumar D, Buwa N, Ganguli S, Thampatty SR, Balasubramanian N, Bhandari R.

Cell Signal. 2016 Aug;28(8):1124-36. doi: 10.1016/j.cellsig.2016.04.011. Epub 2016 Apr 30.

20.

GRAB: a physiologic guanine nucleotide exchange factor for Rab3A, which interacts with inositol hexakisphosphate kinase.

Luo HR, Saiardi A, Nagata E, Ye K, Yu H, Jung TS, Luo X, Jain S, Sawa A, Snyder SH.

Neuron. 2001 Aug 16;31(3):439-51.

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