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Items: 1 to 20 of 117

1.

Pirt, a TRPV1 modulator, is required for histamine-dependent and -independent itch.

Patel KN, Liu Q, Meeker S, Undem BJ, Dong X.

PLoS One. 2011;6(5):e20559. doi: 10.1371/journal.pone.0020559. Epub 2011 May 31.

2.

Pirt, a phosphoinositide-binding protein, functions as a regulatory subunit of TRPV1.

Kim AY, Tang Z, Liu Q, Patel KN, Maag D, Geng Y, Dong X.

Cell. 2008 May 2;133(3):475-85. doi: 10.1016/j.cell.2008.02.053.

3.

Transient Receptor Potential Vanilloid 4 Ion Channel Functions as a Pruriceptor in Epidermal Keratinocytes to Evoke Histaminergic Itch.

Chen Y, Fang Q, Wang Z, Zhang JY, MacLeod AS, Hall RP, Liedtke WB.

J Biol Chem. 2016 May 6;291(19):10252-62. doi: 10.1074/jbc.M116.716464. Epub 2016 Mar 9.

4.

Protein kinase Cδ mediates histamine-evoked itch and responses in pruriceptors.

Valtcheva MV, Davidson S, Zhao C, Leitges M, Gereau RW 4th.

Mol Pain. 2015 Jan 6;11:1. doi: 10.1186/1744-8069-11-1.

5.

Eact, a small molecule activator of TMEM16A, activates TRPV1 and elicits pain- and itch-related behaviours.

Liu S, Feng J, Luo J, Yang P, Brett TJ, Hu H.

Br J Pharmacol. 2016 Apr;173(7):1208-18. doi: 10.1111/bph.13420. Epub 2016 Mar 1. Erratum in: Br J Pharmacol. 2016 Sep;173(18):2808.

6.

A sensory neuron-expressed IL-31 receptor mediates T helper cell-dependent itch: Involvement of TRPV1 and TRPA1.

Cevikbas F, Wang X, Akiyama T, Kempkes C, Savinko T, Antal A, Kukova G, Buhl T, Ikoma A, Buddenkotte J, Soumelis V, Feld M, Alenius H, Dillon SR, Carstens E, Homey B, Basbaum A, Steinhoff M.

J Allergy Clin Immunol. 2014 Feb;133(2):448-60. doi: 10.1016/j.jaci.2013.10.048. Epub 2013 Dec 25.

7.

Lysophosphatidic acid-induced itch is mediated by signalling of LPA5 receptor, phospholipase D and TRPA1/TRPV1.

Kittaka H, Uchida K, Fukuta N, Tominaga M.

J Physiol. 2017 Apr 15;595(8):2681-2698. doi: 10.1113/JP273961. Epub 2017 Mar 22.

PMID:
28176353
8.

TLR3 deficiency impairs spinal cord synaptic transmission, central sensitization, and pruritus in mice.

Liu T, Berta T, Xu ZZ, Park CK, Zhang L, Lü N, Liu Q, Liu Y, Gao YJ, Liu YC, Ma Q, Dong X, Ji RR.

J Clin Invest. 2012 Jun;122(6):2195-207. doi: 10.1172/JCI45414. Epub 2012 May 8.

9.

TRPV1 and PLC Participate in Histamine H4 Receptor-Induced Itch.

Jian T, Yang N, Yang Y, Zhu C, Yuan X, Yu G, Wang C, Wang Z, Shi H, Tang M, He Q, Lan L, Wu G, Tang Z.

Neural Plast. 2016;2016:1682972. doi: 10.1155/2016/1682972. Epub 2015 Dec 24.

10.

Analysis of cellular and behavioral responses to imiquimod reveals a unique itch pathway in transient receptor potential vanilloid 1 (TRPV1)-expressing neurons.

Kim SJ, Park GH, Kim D, Lee J, Min H, Wall E, Lee CJ, Simon MI, Lee SJ, Han SK.

Proc Natl Acad Sci U S A. 2011 Feb 22;108(8):3371-6. doi: 10.1073/pnas.1019755108. Epub 2011 Feb 7.

11.

TRPV1-expressing primary afferents generate behavioral responses to pruritogens via multiple mechanisms.

Imamachi N, Park GH, Lee H, Anderson DJ, Simon MI, Basbaum AI, Han SK.

Proc Natl Acad Sci U S A. 2009 Jul 7;106(27):11330-5. doi: 10.1073/pnas.0905605106. Epub 2009 Jun 29.

12.

TRPA1 is required for histamine-independent, Mas-related G protein-coupled receptor-mediated itch.

Wilson SR, Gerhold KA, Bifolck-Fisher A, Liu Q, Patel KN, Dong X, Bautista DM.

Nat Neurosci. 2011 May;14(5):595-602. doi: 10.1038/nn.2789. Epub 2011 Apr 3.

13.

Excitation and modulation of TRPA1, TRPV1, and TRPM8 channel-expressing sensory neurons by the pruritogen chloroquine.

Than JY, Li L, Hasan R, Zhang X.

J Biol Chem. 2013 May 3;288(18):12818-27. doi: 10.1074/jbc.M113.450072. Epub 2013 Mar 18.

14.

Potentiation of the transient receptor potential vanilloid 1 channel contributes to pruritogenesis in a rat model of liver disease.

Belghiti M, Estévez-Herrera J, Giménez-Garzó C, González-Usano A, Montoliu C, Ferrer-Montiel A, Felipo V, Planells-Cases R.

J Biol Chem. 2013 Apr 5;288(14):9675-85. doi: 10.1074/jbc.M113.455162. Epub 2013 Feb 13.

15.

Localization of the PIP2 sensor of TRPV1 ion channels.

Ufret-Vincenty CA, Klein RM, Hua L, Angueyra J, Gordon SE.

J Biol Chem. 2011 Mar 18;286(11):9688-98. doi: 10.1074/jbc.M110.192526. Epub 2011 Jan 11.

16.

The cells and circuitry for itch responses in mice.

Mishra SK, Hoon MA.

Science. 2013 May 24;340(6135):968-71. doi: 10.1126/science.1233765.

17.

Pirt contributes to uterine contraction-induced pain in mice.

Wang C, Wang Z, Yang Y, Zhu C, Wu G, Yu G, Jian T, Yang N, Shi H, Tang M, He Q, Lan L, Liu Q, Guan Y, Dong X, Duan J, Tang Z.

Mol Pain. 2015 Sep 17;11:57. doi: 10.1186/s12990-015-0054-x.

18.

Involvement of TRPV4 in Serotonin-Evoked Scratching.

Akiyama T, Ivanov M, Nagamine M, Davoodi A, Carstens MI, Ikoma A, Cevikbas F, Kempkes C, Buddenkotte J, Steinhoff M, Carstens E.

J Invest Dermatol. 2016 Jan;136(1):154-60. doi: 10.1038/JID.2015.388.

19.

The distinct roles of two GPCRs, MrgprC11 and PAR2, in itch and hyperalgesia.

Liu Q, Weng HJ, Patel KN, Tang Z, Bai H, Steinhoff M, Dong X.

Sci Signal. 2011 Jul 12;4(181):ra45. doi: 10.1126/scisignal.2001925.

20.

Caffeic acid exhibits anti-pruritic effects by inhibition of multiple itch transmission pathways in mice.

Pradhananga S, Shim WS.

Eur J Pharmacol. 2015 Sep 5;762:313-21. doi: 10.1016/j.ejphar.2015.06.006. Epub 2015 Jun 6.

PMID:
26057691

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