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Items: 1 to 20 of 121

1.

High throughput determination of TGFβ1/SMAD3 targets in A549 lung epithelial cells.

Zhang Y, Handley D, Kaplan T, Yu H, Bais AS, Richards T, Pandit KV, Zeng Q, Benos PV, Friedman N, Eickelberg O, Kaminski N.

PLoS One. 2011;6(5):e20319. doi: 10.1371/journal.pone.0020319. Epub 2011 May 20.

2.

Interactions between β-catenin and transforming growth factor-β signaling pathways mediate epithelial-mesenchymal transition and are dependent on the transcriptional co-activator cAMP-response element-binding protein (CREB)-binding protein (CBP).

Zhou B, Liu Y, Kahn M, Ann DK, Han A, Wang H, Nguyen C, Flodby P, Zhong Q, Krishnaveni MS, Liebler JM, Minoo P, Crandall ED, Borok Z.

J Biol Chem. 2012 Mar 2;287(10):7026-38. doi: 10.1074/jbc.M111.276311. Epub 2012 Jan 12.

3.

TGFβ1 induces IL-6 and inhibits IL-8 release in human bronchial epithelial cells: the role of Smad2/3.

Ge Q, Moir LM, Black JL, Oliver BG, Burgess JK.

J Cell Physiol. 2010 Nov;225(3):846-54. doi: 10.1002/jcp.22295.

PMID:
20607798
4.

miR‑221 targets HMGA2 to inhibit bleomycin‑induced pulmonary fibrosis by regulating TGF‑β1/Smad3-induced EMT.

Wang YC, Liu JS, Tang HK, Nie J, Zhu JX, Wen LL, Guo QL.

Int J Mol Med. 2016 Oct;38(4):1208-16. doi: 10.3892/ijmm.2016.2705. Epub 2016 Aug 11.

PMID:
27513632
5.
6.

Transgelin is a direct target of TGF-beta/Smad3-dependent epithelial cell migration in lung fibrosis.

Yu H, Königshoff M, Jayachandran A, Handley D, Seeger W, Kaminski N, Eickelberg O.

FASEB J. 2008 Jun;22(6):1778-89. doi: 10.1096/fj.07-083857. Epub 2008 Feb 1.

PMID:
18245174
7.

Amplification of TGFβ Induced ITGB6 Gene Transcription May Promote Pulmonary Fibrosis.

Tatler AL, Goodwin AT, Gbolahan O, Saini G, Porte J, John AE, Clifford RL, Violette SM, Weinreb PH, Parfrey H, Wolters PJ, Gauldie J, Kolb M, Jenkins G.

PLoS One. 2016 Aug 5;11(8):e0158047. doi: 10.1371/journal.pone.0158047. eCollection 2016.

8.
9.

Astaxanthin prevents TGFβ1-induced pro-fibrogenic gene expression by inhibiting Smad3 activation in hepatic stellate cells.

Yang Y, Kim B, Park YK, Koo SI, Lee JY.

Biochim Biophys Acta. 2015 Jan;1850(1):178-85. doi: 10.1016/j.bbagen.2014.10.014. Epub 2014 Oct 23.

PMID:
25450180
10.

The TGFβ1 pathway is required for NFκB dependent gene expression in mouse keratinocytes.

Hogan KA, Ravindran A, Podolsky MA, Glick AB.

Cytokine. 2013 Dec;64(3):652-9. doi: 10.1016/j.cyto.2013.09.004. Epub 2013 Sep 24.

11.
12.

TGF-β-activated SMAD3/4 complex transcriptionally upregulates N-cadherin expression in non-small cell lung cancer.

Yang H, Wang L, Zhao J, Chen Y, Lei Z, Liu X, Xia W, Guo L, Zhang HT.

Lung Cancer. 2015 Mar;87(3):249-57. doi: 10.1016/j.lungcan.2014.12.015. Epub 2015 Jan 5.

PMID:
25595426
13.

Transforming growth factor-β1 induces expression of human coagulation factor XII via Smad3 and JNK signaling pathways in human lung fibroblasts.

Jablonska E, Markart P, Zakrzewicz D, Preissner KT, Wygrecka M.

J Biol Chem. 2010 Apr 9;285(15):11638-51. doi: 10.1074/jbc.M109.045963. Epub 2010 Feb 8.

14.

Platelet-Derived Growth Factor and Transforming Growth Factor β1 Regulate ARDS-Associated Lung Fibrosis Through Distinct Signaling Pathways.

Deng X, Jin K, Li Y, Gu W, Liu M, Zhou L.

Cell Physiol Biochem. 2015;36(3):937-46. doi: 10.1159/000430268. Epub 2015 Jun 12.

15.

Phosphoproteome profiling of transforming growth factor (TGF)-beta signaling: abrogation of TGFbeta1-dependent phosphorylation of transcription factor-II-I (TFII-I) enhances cooperation of TFII-I and Smad3 in transcription.

Stasyk T, Dubrovska A, Lomnytska M, Yakymovych I, Wernstedt C, Heldin CH, Hellman U, Souchelnytskyi S.

Mol Biol Cell. 2005 Oct;16(10):4765-80. Epub 2005 Jul 29.

16.

The differential role of Smad2 and Smad3 in the regulation of pro-fibrotic TGFbeta1 responses in human proximal-tubule epithelial cells.

Phanish MK, Wahab NA, Colville-Nash P, Hendry BM, Dockrell ME.

Biochem J. 2006 Jan 15;393(Pt 2):601-7.

17.

Transforming growth factor-{beta}1 induces Smad3-dependent {beta}1 integrin gene expression in epithelial-to-mesenchymal transition during chronic tubulointerstitial fibrosis.

Yeh YC, Wei WC, Wang YK, Lin SC, Sung JM, Tang MJ.

Am J Pathol. 2010 Oct;177(4):1743-54. doi: 10.2353/ajpath.2010.091183. Epub 2010 Aug 13.

18.

Saponins from the roots of Platycodon grandiflorum suppresses TGFβ1-induced epithelial-mesenchymal transition via repression of PI3K/Akt, ERK1/2 and Smad2/3 pathway in human lung carcinoma A549 cells.

Choi JH, Hwang YP, Kim HG, Khanal T, Do MT, Jin SW, Han HJ, Lee HS, Lee YC, Chung YC, Jeong TC, Jeong HG.

Nutr Cancer. 2014;66(1):140-51. doi: 10.1080/01635581.2014.853087. Epub 2013 Dec 16.

PMID:
24341702
19.

Transforming growth factor-beta inhibits pulmonary surfactant protein B gene transcription through SMAD3 interactions with NKX2.1 and HNF-3 transcription factors.

Li C, Zhu NL, Tan RC, Ballard PL, Derynck R, Minoo P.

J Biol Chem. 2002 Oct 11;277(41):38399-408. Epub 2002 Aug 2.

20.

RACK1 binds to Smad3 to modulate transforming growth factor-beta1-stimulated alpha2(I) collagen transcription in renal tubular epithelial cells.

Okano K, Schnaper HW, Bomsztyk K, Hayashida T.

J Biol Chem. 2006 Sep 8;281(36):26196-204. Epub 2006 Jul 18.

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