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Items: 1 to 20 of 90

1.

Mechanotransduction and the regulation of mTORC1 signaling in skeletal muscle.

Hornberger TA.

Int J Biochem Cell Biol. 2011 Sep;43(9):1267-76. doi: 10.1016/j.biocel.2011.05.007. Epub 2011 May 19. Review.

2.

Regulation of mTOR by mechanically induced signaling events in skeletal muscle.

Hornberger TA, Sukhija KB, Chien S.

Cell Cycle. 2006 Jul;5(13):1391-6. Epub 2006 Jul 1. Review.

PMID:
16855395
3.

The role of diacylglycerol kinase ΞΆ and phosphatidic acid in the mechanical activation of mammalian target of rapamycin (mTOR) signaling and skeletal muscle hypertrophy.

You JS, Lincoln HC, Kim CR, Frey JW, Goodman CA, Zhong XP, Hornberger TA.

J Biol Chem. 2014 Jan 17;289(3):1551-63. doi: 10.1074/jbc.M113.531392. Epub 2013 Dec 3.

4.

The role of mTORC1 in regulating protein synthesis and skeletal muscle mass in response to various mechanical stimuli.

Goodman CA.

Rev Physiol Biochem Pharmacol. 2014;166:43-95. doi: 10.1007/112_2013_17. Review.

PMID:
24442322
5.

The role of phospholipase D and phosphatidic acid in the mechanical activation of mTOR signaling in skeletal muscle.

Hornberger TA, Chu WK, Mak YW, Hsiung JW, Huang SA, Chien S.

Proc Natl Acad Sci U S A. 2006 Mar 21;103(12):4741-6. Epub 2006 Mar 14.

6.

Mechanical stimulation induces mTOR signaling via an ERK-independent mechanism: implications for a direct activation of mTOR by phosphatidic acid.

You JS, Frey JW, Hornberger TA.

PLoS One. 2012;7(10):e47258. doi: 10.1371/journal.pone.0047258. Epub 2012 Oct 15.

7.

Distinct amino acid-sensing mTOR pathways regulate skeletal myogenesis.

Yoon MS, Chen J.

Mol Biol Cell. 2013 Dec;24(23):3754-63. doi: 10.1091/mbc.E13-06-0353. Epub 2013 Sep 25.

8.

Phospholipase D mediates nutrient input to mammalian target of rapamycin complex 1 (mTORC1).

Xu L, Salloum D, Medlin PS, Saqcena M, Yellen P, Perrella B, Foster DA.

J Biol Chem. 2011 Jul 22;286(29):25477-86. doi: 10.1074/jbc.M111.249631. Epub 2011 May 28.

9.

The role of phosphoinositide 3-kinase and phosphatidic acid in the regulation of mammalian target of rapamycin following eccentric contractions.

O'Neil TK, Duffy LR, Frey JW, Hornberger TA.

J Physiol. 2009 Jul 15;587(Pt 14):3691-701. doi: 10.1113/jphysiol.2009.173609. Epub 2009 May 26.

10.

Amino acid regulation of TOR complex 1.

Avruch J, Long X, Ortiz-Vega S, Rapley J, Papageorgiou A, Dai N.

Am J Physiol Endocrinol Metab. 2009 Apr;296(4):E592-602. doi: 10.1152/ajpendo.90645.2008. Epub 2008 Sep 2. Review.

11.

Early activation of mTORC1 signalling in response to mechanical overload is independent of phosphoinositide 3-kinase/Akt signalling.

Miyazaki M, McCarthy JJ, Fedele MJ, Esser KA.

J Physiol. 2011 Apr 1;589(Pt 7):1831-46. doi: 10.1113/jphysiol.2011.205658. Epub 2011 Feb 7.

12.

The mechanical activation of mTOR signaling: an emerging role for late endosome/lysosomal targeting.

Jacobs BL, Goodman CA, Hornberger TA.

J Muscle Res Cell Motil. 2014 Feb;35(1):11-21. doi: 10.1007/s10974-013-9367-4. Epub 2013 Oct 29. Review.

13.

Phosphatidic acid activates mammalian target of rapamycin complex 1 (mTORC1) kinase by displacing FK506 binding protein 38 (FKBP38) and exerting an allosteric effect.

Yoon MS, Sun Y, Arauz E, Jiang Y, Chen J.

J Biol Chem. 2011 Aug 26;286(34):29568-74. doi: 10.1074/jbc.M111.262816. Epub 2011 Jul 7.

14.

The mechanistic and ergogenic effects of phosphatidic acid in skeletal muscle.

Shad BJ, Smeuninx B, Atherton PJ, Breen L.

Appl Physiol Nutr Metab. 2015 Dec;40(12):1233-41. doi: 10.1139/apnm-2015-0350. Epub 2015 Sep 21. Review.

PMID:
26566242
15.

Class III PI-3-kinase activates phospholipase D in an amino acid-sensing mTORC1 pathway.

Yoon MS, Du G, Backer JM, Frohman MA, Chen J.

J Cell Biol. 2011 Oct 31;195(3):435-47. doi: 10.1083/jcb.201107033. Epub 2011 Oct 24.

16.

mTOR signaling: PLD takes center stage.

Sun Y, Chen J.

Cell Cycle. 2008 Oct;7(20):3118-23. Epub 2008 Oct 27. Review.

PMID:
18927511
17.

The abundance and activation of mTORC1 regulators in skeletal muscle of neonatal pigs are modulated by insulin, amino acids, and age.

Suryawan A, Davis TA.

J Appl Physiol (1985). 2010 Nov;109(5):1448-54. doi: 10.1152/japplphysiol.00428.2010. Epub 2010 Aug 19.

18.

Bone and skeletal muscle: Key players in mechanotransduction and potential overlapping mechanisms.

Goodman CA, Hornberger TA, Robling AG.

Bone. 2015 Nov;80:24-36. doi: 10.1016/j.bone.2015.04.014. Review.

19.

Phospholipase D and mTORC1: nutrients are what bring them together.

Wiczer BM, Thomas G.

Sci Signal. 2012 Mar 27;5(217):pe13. doi: 10.1126/scisignal.2003019.

PMID:
22457329
20.

[The role of mTOR in the regulation of skeletal muscle metabolism].

Gol'berg ND, Druzhevskaia AM, Rogozkin VA, Akhmetov II.

Fiziol Cheloveka. 2014 Sep-Oct;40(5):123-32. Review. Russian.

PMID:
25711103

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