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Items: 1 to 20 of 106

1.

Structure of respiratory syncytial virus fusion glycoprotein in the postfusion conformation reveals preservation of neutralizing epitopes.

McLellan JS, Yang Y, Graham BS, Kwong PD.

J Virol. 2011 Aug;85(15):7788-96. doi: 10.1128/JVI.00555-11. Epub 2011 May 25.

2.

Structure of a major antigenic site on the respiratory syncytial virus fusion glycoprotein in complex with neutralizing antibody 101F.

McLellan JS, Chen M, Chang JS, Yang Y, Kim A, Graham BS, Kwong PD.

J Virol. 2010 Dec;84(23):12236-44. doi: 10.1128/JVI.01579-10. Epub 2010 Sep 29.

3.

A monomeric uncleaved respiratory syncytial virus F antigen retains prefusion-specific neutralizing epitopes.

Swanson KA, Balabanis K, Xie Y, Aggarwal Y, Palomo C, Mas V, Metrick C, Yang H, Shaw CA, Melero JA, Dormitzer PR, Carfi A.

J Virol. 2014 Oct;88(20):11802-10. doi: 10.1128/JVI.01225-14. Epub 2014 Jul 30.

4.

Structural basis for immunization with postfusion respiratory syncytial virus fusion F glycoprotein (RSV F) to elicit high neutralizing antibody titers.

Swanson KA, Settembre EC, Shaw CA, Dey AK, Rappuoli R, Mandl CW, Dormitzer PR, Carfi A.

Proc Natl Acad Sci U S A. 2011 Jun 7;108(23):9619-24. doi: 10.1073/pnas.1106536108. Epub 2011 May 17.

5.

Characterization of a Prefusion-Specific Antibody That Recognizes a Quaternary, Cleavage-Dependent Epitope on the RSV Fusion Glycoprotein.

Gilman MS, Moin SM, Mas V, Chen M, Patel NK, Kramer K, Zhu Q, Kabeche SC, Kumar A, Palomo C, Beaumont T, Baxa U, Ulbrandt ND, Melero JA, Graham BS, McLellan JS.

PLoS Pathog. 2015 Jul 10;11(7):e1005035. doi: 10.1371/journal.ppat.1005035. eCollection 2015 Jul.

6.

Structural basis of respiratory syncytial virus neutralization by motavizumab.

McLellan JS, Chen M, Kim A, Yang Y, Graham BS, Kwong PD.

Nat Struct Mol Biol. 2010 Feb;17(2):248-50. doi: 10.1038/nsmb.1723. Epub 2010 Jan 24.

7.

Influence of Respiratory Syncytial Virus F Glycoprotein Conformation on Induction of Protective Immune Responses.

Palomo C, Mas V, Thom M, Vázquez M, Cano O, Terrón MC, Luque D, Taylor G, Melero JA.

J Virol. 2016 May 12;90(11):5485-98. doi: 10.1128/JVI.00338-16. Print 2016 Jun 1.

8.

Engineering, Structure and Immunogenicity of the Human Metapneumovirus F Protein in the Postfusion Conformation.

Más V, Rodriguez L, Olmedillas E, Cano O, Palomo C, Terrón MC, Luque D, Melero JA, McLellan JS.

PLoS Pathog. 2016 Sep 9;12(9):e1005859. doi: 10.1371/journal.ppat.1005859. eCollection 2016 Sep.

9.

Design and characterization of epitope-scaffold immunogens that present the motavizumab epitope from respiratory syncytial virus.

McLellan JS, Correia BE, Chen M, Yang Y, Graham BS, Schief WR, Kwong PD.

J Mol Biol. 2011 Jun 24;409(5):853-66. doi: 10.1016/j.jmb.2011.04.044. Epub 2011 Apr 27.

10.

Neutralizing epitopes on the respiratory syncytial virus fusion glycoprotein.

McLellan JS.

Curr Opin Virol. 2015 Apr;11:70-5. doi: 10.1016/j.coviro.2015.03.002. Epub 2015 Mar 26. Review.

11.

Structure of RSV fusion glycoprotein trimer bound to a prefusion-specific neutralizing antibody.

McLellan JS, Chen M, Leung S, Graepel KW, Du X, Yang Y, Zhou T, Baxa U, Yasuda E, Beaumont T, Kumar A, Modjarrad K, Zheng Z, Zhao M, Xia N, Kwong PD, Graham BS.

Science. 2013 May 31;340(6136):1113-7. doi: 10.1126/science.1234914. Epub 2013 Apr 25.

12.

Stability Characterization of a Vaccine Antigen Based on the Respiratory Syncytial Virus Fusion Glycoprotein.

Flynn JA, Durr E, Swoyer R, Cejas PJ, Horton MS, Galli JD, Cosmi SA, Espeseth AS, Bett AJ, Zhang L.

PLoS One. 2016 Oct 20;11(10):e0164789. doi: 10.1371/journal.pone.0164789. eCollection 2016.

13.

Discovery and Characterization of Phage Display-Derived Human Monoclonal Antibodies against RSV F Glycoprotein.

Chen Z, Zhang L, Tang A, Callahan C, Pristatsky P, Swoyer R, Cejas P, Nahas D, Galli J, Cosmi S, DiStefano D, Hoang VM, Bett A, Casimiro D, Vora KA.

PLoS One. 2016 Jun 3;11(6):e0156798. doi: 10.1371/journal.pone.0156798. eCollection 2016.

14.

Respiratory syncytial virus-neutralizing monoclonal antibodies motavizumab and palivizumab inhibit fusion.

Huang K, Incognito L, Cheng X, Ulbrandt ND, Wu H.

J Virol. 2010 Aug;84(16):8132-40. doi: 10.1128/JVI.02699-09. Epub 2010 Jun 2.

15.

Characterization of neutralizing affinity-matured human respiratory syncytial virus F binding antibodies in the sub-picomolar affinity range.

Canziani GA, Melero JA, Lacy ER.

J Mol Recognit. 2012 Mar;25(3):136-46. doi: 10.1002/jmr.2149.

PMID:
22407977
16.

Characterization of Pre-F-GCN4t, a Modified Human Respiratory Syncytial Virus Fusion Protein Stabilized in a Noncleaved Prefusion Conformation.

Blais N, Gagné M, Hamuro Y, Rheault P, Boyer M, Steff AM, Baudoux G, Dewar V, Demers J, Ruelle JL, Martin D.

J Virol. 2017 Jun 9;91(13). pii: e02437-16. doi: 10.1128/JVI.02437-16. Print 2017 Jul 1.

17.

Evaluation of a synthetic peptide as a replacement for the recombinant fusion protein of respiratory syncytial virus in a potency ELISA.

McGivney JB 4th, Bishop E, Miller K, Casas-Finet J, Yang H, Wei Z, Strouse R, Schenerman M.

J Pharm Biomed Anal. 2011 Feb 20;54(3):572-6. doi: 10.1016/j.jpba.2010.09.008. Epub 2010 Sep 16.

PMID:
20943340
18.

Murine immune responses to virus-like particle-associated pre- and postfusion forms of the respiratory syncytial virus F protein.

McGinnes Cullen L, Schmidt MR, Kenward SA, Woodland RT, Morrison TG.

J Virol. 2015 Jul;89(13):6835-47. doi: 10.1128/JVI.00384-15. Epub 2015 Apr 22.

19.

Mechanism of neutralization of herpes simplex virus by antibodies directed at the fusion domain of glycoprotein B.

Cairns TM, Fontana J, Huang ZY, Whitbeck JC, Atanasiu D, Rao S, Shelly SS, Lou H, Ponce de Leon M, Steven AC, Eisenberg RJ, Cohen GH.

J Virol. 2014 Mar;88(5):2677-89. doi: 10.1128/JVI.03200-13. Epub 2013 Dec 18.

20.

A protective and safe intranasal RSV vaccine based on a recombinant prefusion-like form of the F protein bound to bacterium-like particles.

Rigter A, Widjaja I, Versantvoort H, Coenjaerts FE, van Roosmalen M, Leenhouts K, Rottier PJ, Haijema BJ, de Haan CA.

PLoS One. 2013 Aug 12;8(8):e71072. doi: 10.1371/journal.pone.0071072. eCollection 2013.

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