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Items: 1 to 20 of 110

1.

Identification of novel genes involved in sarcopenia through RNAi screening in Caenorhabditis elegans.

Kashyap L, Perera S, Fisher AL.

J Gerontol A Biol Sci Med Sci. 2012 Jan;67(1):56-65. doi: 10.1093/gerona/glr072. Epub 2011 May 17.

2.

Genes that shape the course of ageing.

Kirkwood TB.

Trends Endocrinol Metab. 2003 Oct;14(8):345-7. Review.

PMID:
14516929
3.
4.

SHC-1/p52Shc targets the insulin/IGF-1 and JNK signaling pathways to modulate life span and stress response in C. elegans.

Neumann-Haefelin E, Qi W, Finkbeiner E, Walz G, Baumeister R, Hertweck M.

Genes Dev. 2008 Oct 1;22(19):2721-35. doi: 10.1101/gad.478408.

5.

Caenorhabditis elegans EAK-3 inhibits dauer arrest via nonautonomous regulation of nuclear DAF-16/FoxO activity.

Zhang Y, Xu J, Puscau C, Kim Y, Wang X, Alam H, Hu PJ.

Dev Biol. 2008 Mar 15;315(2):290-302. doi: 10.1016/j.ydbio.2007.12.032. Epub 2008 Jan 3.

6.

14-3-3 regulates life span by both DAF-16-dependent and -independent mechanisms in Caenorhabditis elegans.

Araiz C, Ch√Ęteau MT, Galas S.

Exp Gerontol. 2008 Jun;43(6):505-19. doi: 10.1016/j.exger.2008.03.001. Epub 2008 Mar 18.

7.

The zinc-finger protein SEA-2 regulates larval developmental timing and adult lifespan in C. elegans.

Huang X, Zhang H, Zhang H.

Development. 2011 May;138(10):2059-68. doi: 10.1242/dev.057109. Epub 2011 Apr 6.

8.

Regulation of Caenorhabditis elegans RNA interference by the daf-2 insulin stress and longevity signaling pathway.

Wang D, Ruvkun G.

Cold Spring Harb Symp Quant Biol. 2004;69:429-31. No abstract available.

PMID:
16117677
9.

Quantitative mass spectrometry identifies insulin signaling targets in C. elegans.

Dong MQ, Venable JD, Au N, Xu T, Park SK, Cociorva D, Johnson JR, Dillin A, Yates JR 3rd.

Science. 2007 Aug 3;317(5838):660-3.

11.

Proteomic analyses of Caenorhabditis elegans dauer larvae and long-lived daf-2 mutants implicates a shared detoxification system in longevity assurance.

Jones LM, Staffa K, Perally S, LaCourse EJ, Brophy PM, Hamilton JV.

J Proteome Res. 2010 Jun 4;9(6):2871-81. doi: 10.1021/pr9009639.

PMID:
20392130
12.

The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans.

Ogg S, Paradis S, Gottlieb S, Patterson GI, Lee L, Tissenbaum HA, Ruvkun G.

Nature. 1997 Oct 30;389(6654):994-9.

PMID:
9353126
13.

Polyunsaturated fatty acids are involved in regulatory mechanism of fatty acid homeostasis via daf-2/insulin signaling in Caenorhabditis elegans.

Horikawa M, Sakamoto K.

Mol Cell Endocrinol. 2010 Jul 29;323(2):183-92. doi: 10.1016/j.mce.2010.03.004. Epub 2010 Mar 11.

PMID:
20226839
14.

DAF-16 target genes that control C. elegans life-span and metabolism.

Lee SS, Kennedy S, Tolonen AC, Ruvkun G.

Science. 2003 Apr 25;300(5619):644-7. Epub 2003 Apr 10.

15.

DAF-16/FOXO targets genes that regulate tumor growth in Caenorhabditis elegans.

Pinkston-Gosse J, Kenyon C.

Nat Genet. 2007 Nov;39(11):1403-9. Epub 2007 Oct 14.

PMID:
17934462
16.

Lifespan extension in hypomorphic daf-2 mutants of Caenorhabditis elegans is partially mediated by glutathione transferase CeGSTP2-2.

Ayyadevara S, Dandapat A, Singh SP, Benes H, Zimniak L, Shmookler Reis RJ, Zimniak P.

Aging Cell. 2005 Dec;4(6):299-307.

17.

Metabolic Youth in Middle Age: Predicting Aging in Caenorhabditis elegans Using Metabolomics.

Davies SK, Bundy JG, Leroi AM.

J Proteome Res. 2015 Nov 6;14(11):4603-9. doi: 10.1021/acs.jproteome.5b00442. Epub 2015 Oct 13.

18.

Asymmetric arginine dimethylation determines life span in C. elegans by regulating forkhead transcription factor DAF-16.

Takahashi Y, Daitoku H, Hirota K, Tamiya H, Yokoyama A, Kako K, Nagashima Y, Nakamura A, Shimada T, Watanabe S, Yamagata K, Yasuda K, Ishii N, Fukamizu A.

Cell Metab. 2011 May 4;13(5):505-16. doi: 10.1016/j.cmet.2011.03.017.

19.

Direct and indirect gene regulation by a life-extending FOXO protein in C. elegans: roles for GATA factors and lipid gene regulators.

Zhang P, Judy M, Lee SJ, Kenyon C.

Cell Metab. 2013 Jan 8;17(1):85-100. doi: 10.1016/j.cmet.2012.12.013.

20.

Shared transcriptional signature in Caenorhabditis elegans Dauer larvae and long-lived daf-2 mutants implicates detoxification system in longevity assurance.

McElwee JJ, Schuster E, Blanc E, Thomas JH, Gems D.

J Biol Chem. 2004 Oct 22;279(43):44533-43. Epub 2004 Aug 11.

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