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Items: 1 to 20 of 168

1.

The transcription factor BATF controls the global regulators of class-switch recombination in both B cells and T cells.

Ise W, Kohyama M, Schraml BU, Zhang T, Schwer B, Basu U, Alt FW, Tang J, Oltz EM, Murphy TL, Murphy KM.

Nat Immunol. 2011 Jun;12(6):536-43. doi: 10.1038/ni.2037. Epub 2011 May 15.

2.

A BATF-ling connection between B cells and follicular helper T cells.

Ellyard JI, Vinuesa CG.

Nat Immunol. 2011 Jun;12(6):519-20. doi: 10.1038/ni.2042.

PMID:
21587310
3.

B cell Rab7 mediates induction of activation-induced cytidine deaminase expression and class-switching in T-dependent and T-independent antibody responses.

Pone EJ, Lam T, Lou Z, Wang R, Chen Y, Liu D, Edinger AL, Xu Z, Casali P.

J Immunol. 2015 Apr 1;194(7):3065-78. doi: 10.4049/jimmunol.1401896. Epub 2015 Mar 4.

4.

Apurinic/apyrimidinic endonuclease 2 regulates the expansion of germinal centers by protecting against activation-induced cytidine deaminase-independent DNA damage in B cells.

Guikema JE, Linehan EK, Esa N, Tsuchimoto D, Nakabeppu Y, Woodland RT, Schrader CE.

J Immunol. 2014 Jul 15;193(2):931-9. doi: 10.4049/jimmunol.1400002. Epub 2014 Jun 16.

5.

Batf coordinates multiple aspects of B and T cell function required for normal antibody responses.

Betz BC, Jordan-Williams KL, Wang C, Kang SG, Liao J, Logan MR, Kim CH, Taparowsky EJ.

J Exp Med. 2010 May 10;207(5):933-42. doi: 10.1084/jem.20091548. Epub 2010 Apr 26.

6.

HoxC4 binds to the promoter of the cytidine deaminase AID gene to induce AID expression, class-switch DNA recombination and somatic hypermutation.

Park SR, Zan H, Pal Z, Zhang J, Al-Qahtani A, Pone EJ, Xu Z, Mai T, Casali P.

Nat Immunol. 2009 May;10(5):540-50. doi: 10.1038/ni.1725. Epub 2009 Apr 12.

7.

STAT6 is required for IL-4-induced germline Ig gene transcription and switch recombination.

Linehan LA, Warren WD, Thompson PA, Grusby MJ, Berton MT.

J Immunol. 1998 Jul 1;161(1):302-10.

8.

The activating protein 1 transcription factor basic leucine zipper transcription factor, ATF-like (BATF), regulates lymphocyte- and mast cell-driven immune responses in the setting of allergic asthma.

Übel C, Sopel N, Graser A, Hildner K, Reinhardt C, Zimmermann T, Rieker RJ, Maier A, Neurath MF, Murphy KM, Finotto S.

J Allergy Clin Immunol. 2014 Jan;133(1):198-206.e1-9. doi: 10.1016/j.jaci.2013.09.049. Epub 2013 Nov 28.

PMID:
24290279
9.

Transcriptional regulation of germinal center B and plasma cell fates by dynamical control of IRF4.

Ochiai K, Maienschein-Cline M, Simonetti G, Chen J, Rosenthal R, Brink R, Chong AS, Klein U, Dinner AR, Singh H, Sciammas R.

Immunity. 2013 May 23;38(5):918-29. doi: 10.1016/j.immuni.2013.04.009. Epub 2013 May 16.

10.

A negative feedback loop mediated by the Bcl6-cullin 3 complex limits Tfh cell differentiation.

Mathew R, Mao AP, Chiang AH, Bertozzi-Villa C, Bunker JJ, Scanlon ST, McDonald BD, Constantinides MG, Hollister K, Singer JD, Dent AL, Dinner AR, Bendelac A.

J Exp Med. 2014 Jun 2;211(6):1137-51. doi: 10.1084/jem.20132267. Epub 2014 May 26.

11.

Regulation of immunoglobulin class-switch recombination: choreography of noncoding transcription, targeted DNA deamination, and long-range DNA repair.

Matthews AJ, Zheng S, DiMenna LJ, Chaudhuri J.

Adv Immunol. 2014;122:1-57. doi: 10.1016/B978-0-12-800267-4.00001-8. Review.

12.

Induction of activation-induced cytidine deaminase-targeting adaptor 14-3-3γ is mediated by NF-κB-dependent recruitment of CFP1 to the 5'-CpG-3'-rich 14-3-3γ promoter and is sustained by E2A.

Mai T, Pone EJ, Li G, Lam TS, Moehlman J, Xu Z, Casali P.

J Immunol. 2013 Aug 15;191(4):1895-906. doi: 10.4049/jimmunol.1300922. Epub 2013 Jul 12.

13.

Dysregulated development of IL-17- and IL-21-expressing follicular helper T cells and increased germinal center formation in the absence of RORγt.

Wichner K, Stauss D, Kampfrath B, Krüger K, Müller G, Rehm A, Lipp M, Höpken UE.

FASEB J. 2016 Feb;30(2):761-74. doi: 10.1096/fj.15-274001. Epub 2015 Oct 23.

14.

The transcription factor BATF operates as an essential differentiation checkpoint in early effector CD8+ T cells.

Kurachi M, Barnitz RA, Yosef N, Odorizzi PM, DiIorio MA, Lemieux ME, Yates K, Godec J, Klatt MG, Regev A, Wherry EJ, Haining WN.

Nat Immunol. 2014 Apr;15(4):373-83. doi: 10.1038/ni.2834. Epub 2014 Mar 2.

15.

B lymphocyte activation by human papillomavirus-like particles directly induces Ig class switch recombination via TLR4-MyD88.

Yang R, Murillo FM, Delannoy MJ, Blosser RL, Yutzy WH 4th, Uematsu S, Takeda K, Akira S, Viscidi RP, Roden RB.

J Immunol. 2005 Jun 15;174(12):7912-9.

16.

The AP-1 transcription factor Batf controls T(H)17 differentiation.

Schraml BU, Hildner K, Ise W, Lee WL, Smith WA, Solomon B, Sahota G, Sim J, Mukasa R, Cemerski S, Hatton RD, Stormo GD, Weaver CT, Russell JH, Murphy TL, Murphy KM.

Nature. 2009 Jul 16;460(7253):405-9. doi: 10.1038/nature08114. Epub 2009 Jul 5.

17.

IFN-gamma-dependent and -independent initiation of switch recombination by NK cells.

Gao N, Dang T, Yuan D.

J Immunol. 2001 Aug 15;167(4):2011-8.

18.

TLR4- and TRIF-dependent stimulation of B lymphocytes by peptide liposomes enables T cell-independent isotype switch in mice.

Pihlgren M, Silva AB, Madani R, Giriens V, Waeckerle-Men Y, Fettelschoss A, Hickman DT, López-Deber MP, Ndao DM, Vukicevic M, Buccarello AL, Gafner V, Chuard N, Reis P, Piorkowska K, Pfeifer A, Kündig TM, Muhs A, Johansen P.

Blood. 2013 Jan 3;121(1):85-94. doi: 10.1182/blood-2012-02-413831. Epub 2012 Nov 8.

19.

Transcription factor IRF4 controls plasma cell differentiation and class-switch recombination.

Klein U, Casola S, Cattoretti G, Shen Q, Lia M, Mo T, Ludwig T, Rajewsky K, Dalla-Favera R.

Nat Immunol. 2006 Jul;7(7):773-82. Epub 2006 Jun 11.

PMID:
16767092
20.

AID dysregulation in lupus-prone MRL/Fas(lpr/lpr) mice increases class switch DNA recombination and promotes interchromosomal c-Myc/IgH loci translocations: modulation by HoxC4.

White CA, Seth Hawkins J, Pone EJ, Yu ES, Al-Qahtani A, Mai T, Zan H, Casali P.

Autoimmunity. 2011 Dec;44(8):585-98. doi: 10.3109/08916934.2011.577128. Epub 2011 May 18. Erratum in: Autoimmunity. 2011 Dec;44(8):664.

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