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Items: 1 to 20 of 72

1.

EAPP modulates the activity of p21 and Chk2.

Andorfer P, Schwarzmayr L, Rotheneder H.

Cell Cycle. 2011 Jul 1;10(13):2077-82.

2.

EAPP: gatekeeper at the crossroad of apoptosis and p21-mediated cell-cycle arrest.

Andorfer P, Rotheneder H.

Oncogene. 2011 Jun 9;30(23):2679-90. doi: 10.1038/onc.2010.639.

3.

Widdrol activates DNA damage checkpoint through the signaling Chk2-p53-Cdc25A-p21-MCM4 pathway in HT29 cells.

Yun HJ, Hyun SK, Park JH, Kim BW, Kwon HJ.

Mol Cell Biochem. 2012 Apr;363(1-2):281-9. doi: 10.1007/s11010-011-1180-z.

PMID:
22160829
4.

14-3-3sigma and p21 synergize to determine DNA damage response following Chk2 inhibition.

Meng S, Arbit T, Veeriah S, Mellinghoff IK, Fang F, Vivanco I, Rohle D, Chan TA.

Cell Cycle. 2009 Jul 15;8(14):2238-46.

PMID:
19502805
5.

Rsf-1, a chromatin remodeling protein, induces DNA damage and promotes genomic instability.

Sheu JJ, Guan B, Choi JH, Lin A, Lee CH, Hsiao YT, Wang TL, Tsai FJ, Shih IeM.

J Biol Chem. 2010 Dec 3;285(49):38260-9. doi: 10.1074/jbc.M110.138735.

6.
7.

The p53-p21WAF1 checkpoint pathway plays a protective role in preventing DNA rereplication induced by abrogation of FOXF1 function.

Lo PK, Lee JS, Sukumar S.

Cell Signal. 2012 Jan;24(1):316-24. doi: 10.1016/j.cellsig.2011.09.017.

8.

Defective Mre11-dependent activation of Chk2 by ataxia telangiectasia mutated in colorectal carcinoma cells in response to replication-dependent DNA double strand breaks.

Takemura H, Rao VA, Sordet O, Furuta T, Miao ZH, Meng L, Zhang H, Pommier Y.

J Biol Chem. 2006 Oct 13;281(41):30814-23.

9.

DNA damage-induced cell cycle regulation and function of novel Chk2 phosphoresidues.

Buscemi G, Carlessi L, Zannini L, Lisanti S, Fontanella E, Canevari S, Delia D.

Mol Cell Biol. 2006 Nov;26(21):7832-45.

10.

E2F1 uses the ATM signaling pathway to induce p53 and Chk2 phosphorylation and apoptosis.

Powers JT, Hong S, Mayhew CN, Rogers PM, Knudsen ES, Johnson DG.

Mol Cancer Res. 2004 Apr;2(4):203-14.

11.

Priming phosphorylation of Chk2 by polo-like kinase 3 (Plk3) mediates its full activation by ATM and a downstream checkpoint in response to DNA damage.

Bahassi el M, Myer DL, McKenney RJ, Hennigan RF, Stambrook PJ.

Mutat Res. 2006 Apr 11;596(1-2):166-76.

PMID:
16481012
12.

Role of the ATM-checkpoint kinase 2 pathway in CDT-mediated apoptosis of gingival epithelial cells.

Alaoui-El-Azher M, Mans JJ, Baker HV, Chen C, Progulske-Fox A, Lamont RJ, Handfield M.

PLoS One. 2010 Jul 23;5(7):e11714. doi: 10.1371/journal.pone.0011714.

14.

Chromium-mediated apoptosis: involvement of DNA-dependent protein kinase (DNA-PK) and differential induction of p53 target genes.

Hill R, Leidal AM, Madureira PA, Gillis LD, Waisman DM, Chiu A, Lee PW.

DNA Repair (Amst). 2008 Sep 1;7(9):1484-99. doi: 10.1016/j.dnarep.2008.05.007. Erratum in: DNA Repair (Amst). 2013 Oct;12(10):870.

PMID:
18602874
15.
16.

E2F1-dependent pathways are involved in amonafide analogue 7-d-induced DNA damage, G2/M arrest, and apoptosis in p53-deficient K562 cells.

Li Y, Shao J, Shen K, Xu Y, Liu J, Qian X.

J Cell Biochem. 2012 Oct;113(10):3165-77. doi: 10.1002/jcb.24194.

PMID:
22593008
17.

Activation of ATM and Chk2 kinases in relation to the amount of DNA strand breaks.

Buscemi G, Perego P, Carenini N, Nakanishi M, Chessa L, Chen J, Khanna K, Delia D.

Oncogene. 2004 Oct 7;23(46):7691-700.

PMID:
15361830
18.

Bendamustine induces G2 cell cycle arrest and apoptosis in myeloma cells: the role of ATM-Chk2-Cdc25A and ATM-p53-p21-pathways.

Gaul L, Mandl-Weber S, Baumann P, Emmerich B, Schmidmaier R.

J Cancer Res Clin Oncol. 2008 Feb;134(2):245-53.

PMID:
17653574
19.

An important role for CDK2 in G1 to S checkpoint activation and DNA damage response in human embryonic stem cells.

Neganova I, Vilella F, Atkinson SP, Lloret M, Passos JF, von Zglinicki T, O'Connor JE, Burks D, Jones R, Armstrong L, Lako M.

Stem Cells. 2011 Apr;29(4):651-9. doi: 10.1002/stem.620.

20.

DNA damage checkpoint kinase Chk2 triggers replicative senescence.

Gire V, Roux P, Wynford-Thomas D, Brondello JM, Dulic V.

EMBO J. 2004 Jul 7;23(13):2554-63.

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