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Items: 1 to 20 of 76

1.

Local interstitial delivery of z-butylidenephthalide by polymer wafers against malignant human gliomas.

Harn HJ, Lin SZ, Lin PC, Liu CY, Liu PY, Chang LF, Yen SY, Hsieh DK, Liu FC, Tai DF, Chiou TW.

Neuro Oncol. 2011 Jun;13(6):635-48. doi: 10.1093/neuonc/nor021. Epub 2011 May 12.

2.

The antitumor effects of Angelica sinensis on malignant brain tumors in vitro and in vivo.

Tsai NM, Lin SZ, Lee CC, Chen SP, Su HC, Chang WL, Harn HJ.

Clin Cancer Res. 2005 May 1;11(9):3475-84.

3.

The natural compound n-butylidenephthalide derived from Angelica sinensis inhibits malignant brain tumor growth in vitro and in vivo.

Tsai NM, Chen YL, Lee CC, Lin PC, Cheng YL, Chang WL, Lin SZ, Harn HJ.

J Neurochem. 2006 Nov;99(4):1251-62. Epub 2006 Sep 20.

4.

Orphan nuclear receptor, Nurr-77 was a possible target gene of butylidenephthalide chemotherapy on glioblastoma multiform brain tumor.

Lin PC, Chen YL, Chiu SC, Yu YL, Chen SP, Chien MH, Chen KY, Chang WL, Lin SZ, Chiou TW, Harn HJ.

J Neurochem. 2008 Aug;106(3):1017-26. doi: 10.1111/j.1471-4159.2008.05432.x. Epub 2008 Apr 17.

5.

Overexpression of the orphan receptor Nur77 and its translocation induced by PCH4 may inhibit malignant glioma cell growth and induce cell apoptosis.

Chang LF, Lin PC, Ho LI, Liu PY, Wu WC, Chiang IP, Chang HW, Lin SZ, Harn YC, Harn HJ, Chiou TW.

J Surg Oncol. 2011 Apr;103(5):442-50. doi: 10.1002/jso.21809. Epub 2011 Jan 18.

PMID:
21246566
6.

The induction of orphan nuclear receptor Nur77 expression by n-butylenephthalide as pharmaceuticals on hepatocellular carcinoma cell therapy.

Chen YL, Jian MH, Lin CC, Kang JC, Chen SP, Lin PC, Hung PJ, Chen JR, Chang WL, Lin SZ, Harn HJ.

Mol Pharmacol. 2008 Oct;74(4):1046-58. doi: 10.1124/mol.107.044800. Epub 2008 Jun 24.

7.

Interstitial delivery of carboplatin via biodegradable polymers is effective against experimental glioma in the rat.

Olivi A, Ewend MG, Utsuki T, Tyler B, Domb AJ, Brat DJ, Brem H.

Cancer Chemother Pharmacol. 1996;39(1-2):90-6.

PMID:
8995504
8.

Determination of Z-butylidenephthalide in plasma by high-performance liquid chromatography.

Ko WC, Yang JY, Chen CM.

J Chromatogr B Biomed Appl. 1996 Oct 25;685(2):379-82.

PMID:
8953184
9.

Effect of butylidenephthalide on calcium mobilization in isolated rat aorta.

Ko WC, Charng CY, Sheu JR, Tzeng SH, Chen CM.

J Pharm Pharmacol. 1998 Dec;50(12):1365-9.

PMID:
10052851
10.

Relaxant effects of butylidenephthalide in isolated dog blood vessels.

Ko WC, Liao CC, Shih CH, Lei CB, Chen CM.

Planta Med. 2002 Nov;68(11):1004-9.

PMID:
12451491
11.

Liposomal n-butylidenephthalide protects the drug from oxidation and enhances its antitumor effects in glioblastoma multiforme.

Lin YL, Chang KF, Huang XF, Hung CL, Chen SC, Chao WR, Liao KW, Tsai NM.

Int J Nanomedicine. 2015 Sep 28;10:6009-20. doi: 10.2147/IJN.S85790. eCollection 2015.

12.

Implantable biodegradable polymers for IUdR radiosensitization of experimental human malignant glioma.

Williams JA, Dillehay LE, Tabassi K, Sipos E, Fahlman C, Brem H.

J Neurooncol. 1997 May;32(3):181-92.

PMID:
9049879
13.

Treatment of malignant gliomas with mitoxantrone-loaded poly (lactide-co-glycolide) microspheres.

Yemisci M, Bozdag S, Cetin M, Söylemezoglu F, Capan Y, Dalkara T, Vural I.

Neurosurgery. 2006 Dec;59(6):1296-302; discussion 1302-3.

PMID:
17277693
14.

Local immunotherapy with interleukin-2 delivered from biodegradable polymer microspheres combined with interstitial chemotherapy: a novel treatment for experimental malignant glioma.

Rhines LD, Sampath P, DiMeco F, Lawson HC, Tyler BM, Hanes J, Olivi A, Brem H.

Neurosurgery. 2003 Apr;52(4):872-9; discussion 879-80.

PMID:
12657184
15.

The PPARγ agonist pioglitazone crosses the blood-brain barrier and reduces tumor growth in a human xenograft model.

Grommes C, Karlo JC, Caprariello A, Blankenship D, Dechant A, Landreth GE.

Cancer Chemother Pharmacol. 2013 Apr;71(4):929-36. doi: 10.1007/s00280-013-2084-2. Epub 2013 Jan 29.

PMID:
23358645
16.

Implantable polymers for tirapazamine treatments of experimental intracranial malignant glioma.

Yuan X, Tabassi K, Williams JA.

Radiat Oncol Investig. 1999;7(4):218-30.

PMID:
10492162
17.

Expression of Nur77 induced by an n-butylidenephthalide derivative promotes apoptosis and inhibits cell growth in oral squamous cell carcinoma.

Liu PY, Sheu JJ, Lin PC, Lin CT, Liu YJ, Ho LI, Chang LF, Wu WC, Chen SR, Chen J, Harn YC, Lin SZ, Tsai CH, Chiou TW, Harn HJ.

Invest New Drugs. 2012 Feb;30(1):79-89. doi: 10.1007/s10637-010-9518-z. Epub 2010 Sep 1.

PMID:
20809206
18.

Butylidenephthalide antagonizes cromakalim-induced systolic pressure reduction in conscious normotensive rats.

Shih CH, Lin YJ, Chen CM, Ko WC.

BMC Complement Altern Med. 2015 Oct 5;15:344. doi: 10.1186/s12906-015-0877-z.

19.

Local delivery of mitoxantrone for the treatment of malignant brain tumors in rats.

DiMeco F, Li KW, Tyler BM, Wolf AS, Brem H, Olivi A.

J Neurosurg. 2002 Nov;97(5):1173-8.

PMID:
12450040
20.

Interstitial taxol delivered from a biodegradable polymer implant against experimental malignant glioma.

Walter KA, Cahan MA, Gur A, Tyler B, Hilton J, Colvin OM, Burger PC, Domb A, Brem H.

Cancer Res. 1994 Apr 15;54(8):2207-12.

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