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The structural features of Trask that mediate its anti-adhesive functions.

Spassov DS, Ahuja D, Wong CH, Moasser MM.

PLoS One. 2011 Apr 29;6(4):e19154. doi: 10.1371/journal.pone.0019154.


A tumor-suppressing function in the epithelial adhesion protein Trask.

Spassov DS, Wong CH, Harris G, McDonough S, Phojanakong P, Wang D, Hann B, Bazarov AV, Yaswen P, Khanafshar E, Moasser MM.

Oncogene. 2012 Jan 26;31(4):419-31. doi: 10.1038/onc.2011.246.


Phosphorylation of Trask by Src kinases inhibits integrin clustering and functions in exclusion with focal adhesion signaling.

Spassov DS, Wong CH, Sergina N, Ahuja D, Fried M, Sheppard D, Moasser MM.

Mol Cell Biol. 2011 Feb;31(4):766-82. doi: 10.1128/MCB.00841-10.


In vivo cleaved CDCP1 promotes early tumor dissemination via complexing with activated β1 integrin and induction of FAK/PI3K/Akt motility signaling.

Casar B, Rimann I, Kato H, Shattil SJ, Quigley JP, Deryugina EI.

Oncogene. 2014 Jan 9;33(2):255-68. doi: 10.1038/onc.2012.547.


Cellular settings mediating Src Substrate switching between focal adhesion kinase tyrosine 861 and CUB-domain-containing protein 1 (CDCP1) tyrosine 734.

Wortmann A, He Y, Christensen ME, Linn M, Lumley JW, Pollock PM, Waterhouse NJ, Hooper JD.

J Biol Chem. 2011 Dec 9;286(49):42303-15. doi: 10.1074/jbc.M111.227462.


Significance of Trask protein interactions in brain metastatic cohorts of lung cancers.

Wu H, Shang LQ, Chen RL, Yang SM, Wang SL, Wang J, Sun G.

Tumour Biol. 2015 Jun;36(6):4181-7. doi: 10.1007/s13277-015-3053-7.


Adhesion signaling by a novel mitotic substrate of src kinases.

Bhatt AS, Erdjument-Bromage H, Tempst P, Craik CS, Moasser MM.

Oncogene. 2005 Aug 11;24(34):5333-43.


Adhesion or plasmin regulates tyrosine phosphorylation of a novel membrane glycoprotein p80/gp140/CUB domain-containing protein 1 in epithelia.

Brown TA, Yang TM, Zaitsevskaia T, Xia Y, Dunn CA, Sigle RO, Knudsen B, Carter WG.

J Biol Chem. 2004 Apr 9;279(15):14772-83.


The transmembrane src substrate Trask is an epithelial protein that signals during anchorage deprivation.

Spassov DS, Baehner FL, Wong CH, McDonough S, Moasser MM.

Am J Pathol. 2009 May;174(5):1756-65. doi: 10.2353/ajpath.2009.080890.


Structure and function of C-CAM1: effects of the cytoplasmic domain on cell aggregation.

Lin SH, Luo W, Earley K, Cheung P, Hixson DC.

Biochem J. 1995 Oct 1;311 ( Pt 1):239-45.


Phosphorylation of the SRC epithelial substrate Trask is tightly regulated in normal epithelia but widespread in many human epithelial cancers.

Wong CH, Baehner FL, Spassov DS, Ahuja D, Wang D, Hann B, Blair J, Shokat K, Welm AL, Moasser MM.

Clin Cancer Res. 2009 Apr 1;15(7):2311-22. doi: 10.1158/1078-0432.CCR-08-2533.


CUB-domain-containing protein 1 overexpression in solid cancers promotes cancer cell growth by activating Src family kinases.

Leroy C, Shen Q, Strande V, Meyer R, McLaughlin ME, Lezan E, Bentires-Alj M, Voshol H, Bonenfant D, Alex Gaither L.

Oncogene. 2015 Oct 29;34(44):5593-8. doi: 10.1038/onc.2015.19.


Structural requirements for cub domain containing protein 1 (CDCP1) and Src dependent cell transformation.

Kollmorgen G, Bossenmaier B, Niederfellner G, Häring HU, Lammers R.

PLoS One. 2012;7(12):e53050. doi: 10.1371/journal.pone.0053050.


CUB-domain-containing protein 1 regulates peritoneal dissemination of gastric scirrhous carcinoma.

Uekita T, Tanaka M, Takigahira M, Miyazawa Y, Nakanishi Y, Kanai Y, Yanagihara K, Sakai R.

Am J Pathol. 2008 Jun;172(6):1729-39. doi: 10.2353/ajpath.2008.070981.


Carcinoembryonic antigen-related cellular adhesion molecule 1 isoforms alternatively inhibit and costimulate human T cell function.

Chen D, Iijima H, Nagaishi T, Nakajima A, Russell S, Raychowdhury R, Morales V, Rudd CE, Utku N, Blumberg RS.

J Immunol. 2004 Mar 15;172(6):3535-43.


Siglec-5 (CD170) can mediate inhibitory signaling in the absence of immunoreceptor tyrosine-based inhibitory motif phosphorylation.

Avril T, Freeman SD, Attrill H, Clarke RG, Crocker PR.

J Biol Chem. 2005 May 20;280(20):19843-51.

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