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Items: 1 to 20 of 111

1.

Idas, a novel phylogenetically conserved geminin-related protein, binds to geminin and is required for cell cycle progression.

Pefani DE, Dimaki M, Spella M, Karantzelis N, Mitsiki E, Kyrousi C, Symeonidou IE, Perrakis A, Taraviras S, Lygerou Z.

J Biol Chem. 2011 Jul 1;286(26):23234-46. doi: 10.1074/jbc.M110.207688. Epub 2011 May 4.

2.

Hoxb4 transduction down-regulates Geminin protein, providing hematopoietic stem and progenitor cells with proliferation potential.

Ohno Y, Yasunaga S, Ohtsubo M, Mori S, Tsumura M, Okada S, Ohta T, Ohtani K, Kobayashi M, Takihara Y.

Proc Natl Acad Sci U S A. 2010 Dec 14;107(50):21529-34. doi: 10.1073/pnas.1011054107. Epub 2010 Nov 22.

3.

The Geminin and Idas coiled coils preferentially form a heterodimer that inhibits Geminin function in DNA replication licensing.

Caillat C, Pefani DE, Gillespie PJ, Taraviras S, Blow JJ, Lygerou Z, Perrakis A.

J Biol Chem. 2013 Nov 1;288(44):31624-34. doi: 10.1074/jbc.M113.491928. Epub 2013 Sep 24.

4.

Inhibition of eukaryotic DNA replication by geminin binding to Cdt1.

Wohlschlegel JA, Dwyer BT, Dhar SK, Cvetic C, Walter JC, Dutta A.

Science. 2000 Dec 22;290(5500):2309-12.

5.

Geminin prevents rereplication during xenopus development.

Kerns SL, Torke SJ, Benjamin JM, McGarry TJ.

J Biol Chem. 2007 Feb 23;282(8):5514-21. Epub 2006 Dec 19.

6.

The cell-cycle regulator geminin inhibits Hox function through direct and polycomb-mediated interactions.

Luo L, Yang X, Takihara Y, Knoetgen H, Kessel M.

Nature. 2004 Feb 19;427(6976):749-53.

PMID:
14973489
7.

Proteolysis of DNA replication licensing factor Cdt1 in S-phase is performed independently of geminin through its N-terminal region.

Nishitani H, Lygerou Z, Nishimoto T.

J Biol Chem. 2004 Jul 16;279(29):30807-16. Epub 2004 May 11.

8.

Mouse geminin inhibits not only Cdt1-MCM6 interactions but also a novel intrinsic Cdt1 DNA binding activity.

Yanagi K, Mizuno T, You Z, Hanaoka F.

J Biol Chem. 2002 Oct 25;277(43):40871-80. Epub 2002 Aug 20.

9.

TIPT2 and geminin interact with basal transcription factors to synergize in transcriptional regulation.

Pitulescu ME, Teichmann M, Luo L, Kessel M.

BMC Biochem. 2009 Jun 10;10:16. doi: 10.1186/1471-2091-10-16.

10.

The Drosophila Geminin homolog: roles for Geminin in limiting DNA replication, in anaphase and in neurogenesis.

Quinn LM, Herr A, McGarry TJ, Richardson H.

Genes Dev. 2001 Oct 15;15(20):2741-54.

11.

A Cdt1-geminin complex licenses chromatin for DNA replication and prevents rereplication during S phase in Xenopus.

Lutzmann M, Maiorano D, Méchali M.

EMBO J. 2006 Dec 13;25(24):5764-74. Epub 2006 Nov 23.

12.

Geminin has dimerization, Cdt1-binding, and destruction domains that are required for biological activity.

Benjamin JM, Torke SJ, Demeler B, McGarry TJ.

J Biol Chem. 2004 Oct 29;279(44):45957-68. Epub 2004 Aug 12.

13.

Cdt1 and geminin in DNA replication initiation.

Caillat C, Perrakis A.

Subcell Biochem. 2012;62:71-87. doi: 10.1007/978-94-007-4572-8_5. Review.

PMID:
22918581
14.

Cell cycle regulation of the licensing activity of Cdt1 in Xenopus laevis.

Maiorano D, Rul W, Méchali M.

Exp Cell Res. 2004 Apr 15;295(1):138-49.

PMID:
15051497
15.

Cdt1 and geminin are down-regulated upon cell cycle exit and are over-expressed in cancer-derived cell lines.

Xouri G, Lygerou Z, Nishitani H, Pachnis V, Nurse P, Taraviras S.

Eur J Biochem. 2004 Aug;271(16):3368-78.

16.

Cell cycle-dependent subcellular translocation of the human DNA licensing inhibitor geminin.

Dimaki M, Xouri G, Symeonidou IE, Sirinian C, Nishitani H, Taraviras S, Lygerou Z.

J Biol Chem. 2013 Aug 16;288(33):23953-63. doi: 10.1074/jbc.M113.453092. Epub 2013 Jun 29.

17.

Geminin is required for zygotic gene expression at the Xenopus mid-blastula transition.

Kerns SL, Schultz KM, Barry KA, Thorne TM, McGarry TJ.

PLoS One. 2012;7(5):e38009. doi: 10.1371/journal.pone.0038009. Epub 2012 May 25.

18.

The replicative regulator protein geminin on chromatin in the HeLa cell cycle.

Kulartz M, Knippers R.

J Biol Chem. 2004 Oct 1;279(40):41686-94. Epub 2004 Jul 28.

19.

Structural basis for inhibition of the replication licensing factor Cdt1 by geminin.

Lee C, Hong B, Choi JM, Kim Y, Watanabe S, Ishimi Y, Enomoto T, Tada S, Kim Y, Cho Y.

Nature. 2004 Aug 19;430(7002):913-7. Epub 2004 Aug 1.

PMID:
15286659
20.

Human geminin promotes pre-RC formation and DNA replication by stabilizing CDT1 in mitosis.

Ballabeni A, Melixetian M, Zamponi R, Masiero L, Marinoni F, Helin K.

EMBO J. 2004 Aug 4;23(15):3122-32. Epub 2004 Jul 15.

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