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Items: 1 to 20 of 119

1.

Protein kinase C mediates platelet secretion and thrombus formation through protein kinase D2.

Konopatskaya O, Matthews SA, Harper MT, Gilio K, Cosemans JM, Williams CM, Navarro MN, Carter DA, Heemskerk JW, Leitges M, Cantrell D, Poole AW.

Blood. 2011 Jul 14;118(2):416-24. doi: 10.1182/blood-2010-10-312199. Epub 2011 Apr 28.

2.

Diverse functions of protein kinase C isoforms in platelet activation and thrombus formation.

Harper MT, Poole AW.

J Thromb Haemost. 2010 Mar;8(3):454-62. doi: 10.1111/j.1538-7836.2009.03722.x. Epub 2009 Dec 11. Review.

3.

CGX1037 is a novel PKC isoform delta selective inhibitor in platelets.

Bhavanasi D, Kostyak JC, Swindle J, Kilpatrick LE, Kunapuli SP.

Platelets. 2015;26(1):2-9. doi: 10.3109/09537104.2013.868877. Epub 2014 Jan 16.

4.

Functional divergence of platelet protein kinase C (PKC) isoforms in thrombus formation on collagen.

Gilio K, Harper MT, Cosemans JM, Konopatskaya O, Munnix IC, Prinzen L, Leitges M, Liu Q, Molkentin JD, Heemskerk JW, Poole AW.

J Biol Chem. 2010 Jul 23;285(30):23410-9. doi: 10.1074/jbc.M110.136176. Epub 2010 May 17.

5.

PKCalpha regulates platelet granule secretion and thrombus formation in mice.

Konopatskaya O, Gilio K, Harper MT, Zhao Y, Cosemans JM, Karim ZA, Whiteheart SW, Molkentin JD, Verkade P, Watson SP, Heemskerk JW, Poole AW.

J Clin Invest. 2009 Feb;119(2):399-407. doi: 10.1172/JCI34665. Epub 2009 Jan 19.

6.

Impact of the serum- and glucocorticoid-inducible kinase 1 on platelet dense granule biogenesis and secretion.

Walker B, Schmid E, Russo A, Schmidt EM, Burk O, Münzer P, Velic A, Macek B, Schaller M, Schwab M, Seabra MC, Gawaz M, Lang F, Borst O.

J Thromb Haemost. 2015 Jul;13(7):1325-34. doi: 10.1111/jth.12998. Epub 2015 Jun 12.

PMID:
25944668
7.

PKCs in thrombus formation.

Zaid Y, Senhaji N, Naya A, Fadainia C, Kojok K.

Pathol Biol (Paris). 2015 Dec;63(6):268-71. doi: 10.1016/j.patbio.2015.09.001. Epub 2015 Oct 23. Review.

PMID:
26476932
8.
9.

Differential role of protein kinase C delta isoform in agonist-induced dense granule secretion in human platelets.

Murugappan S, Tuluc F, Dorsam RT, Shankar H, Kunapuli SP.

J Biol Chem. 2004 Jan 23;279(4):2360-7. Epub 2003 Oct 24.

10.

Impaired activation of platelets lacking protein kinase C-theta isoform.

Nagy B Jr, Bhavaraju K, Getz T, Bynagari YS, Kim S, Kunapuli SP.

Blood. 2009 Mar 12;113(11):2557-67. doi: 10.1182/blood-2008-07-169268. Epub 2009 Jan 22.

11.

Protein kinase C-theta in platelet activation.

Cohen S, Braiman A, Shubinsky G, Isakov N.

FEBS Lett. 2011 Oct 20;585(20):3208-15. doi: 10.1016/j.febslet.2011.09.014. Epub 2011 Sep 17. Review.

12.

Impaired thrombin-induced platelet activation and thrombus formation in mice lacking the Ca(2+)-dependent tyrosine kinase Pyk2.

Canobbio I, Cipolla L, Consonni A, Momi S, Guidetti G, Oliviero B, Falasca M, Okigaki M, Balduini C, Gresele P, Torti M.

Blood. 2013 Jan 24;121(4):648-57. doi: 10.1182/blood-2012-06-438762. Epub 2012 Nov 21.

13.

Submaximal inhibition of protein kinase C restores ADP-induced dense granule secretion in platelets in the presence of Ca2+.

Unsworth AJ, Smith H, Gissen P, Watson SP, Pears CJ.

J Biol Chem. 2011 Jun 17;286(24):21073-82. doi: 10.1074/jbc.M110.187138. Epub 2011 Apr 13.

14.

Genetic analysis of the role of protein kinase Ctheta in platelet function and thrombus formation.

Hall KJ, Harper MT, Gilio K, Cosemans JM, Heemskerk JW, Poole AW.

PLoS One. 2008 Sep 25;3(9):e3277. doi: 10.1371/journal.pone.0003277.

15.

A dual role for integrin-linked kinase in platelets: regulating integrin function and alpha-granule secretion.

Tucker KL, Sage T, Stevens JM, Jordan PA, Jones S, Barrett NE, St-Arnaud R, Frampton J, Dedhar S, Gibbins JM.

Blood. 2008 Dec 1;112(12):4523-31. doi: 10.1182/blood-2008-03-148502. Epub 2008 Sep 4.

16.

Protein kinase C regulation of 12-lipoxygenase-mediated human platelet activation.

Yeung J, Apopa PL, Vesci J, Kenyon V, Rai G, Jadhav A, Simeonov A, Holman TR, Maloney DJ, Boutaud O, Holinstat M.

Mol Pharmacol. 2012 Mar;81(3):420-30. doi: 10.1124/mol.111.075630. Epub 2011 Dec 9.

17.

Dual role of platelet protein kinase C in thrombus formation: stimulation of pro-aggregatory and suppression of procoagulant activity in platelets.

Strehl A, Munnix IC, Kuijpers MJ, van der Meijden PE, Cosemans JM, Feijge MA, Nieswandt B, Heemskerk JW.

J Biol Chem. 2007 Mar 9;282(10):7046-55. Epub 2007 Jan 8.

18.

Lyn, PKC-delta, SHIP-1 interactions regulate GPVI-mediated platelet-dense granule secretion.

Chari R, Kim S, Murugappan S, Sanjay A, Daniel JL, Kunapuli SP.

Blood. 2009 Oct 1;114(14):3056-63. doi: 10.1182/blood-2008-11-188516. Epub 2009 Jul 8.

19.

Dual regulation of glycogen synthase kinase 3 (GSK3)α/β by protein kinase C (PKC)α and Akt promotes thrombin-mediated integrin αIIbβ3 activation and granule secretion in platelets.

Moore SF, van den Bosch MT, Hunter RW, Sakamoto K, Poole AW, Hers I.

J Biol Chem. 2013 Feb 8;288(6):3918-28. doi: 10.1074/jbc.M112.429936. Epub 2012 Dec 13.

20.

Protein kinase Cδ mediates the activation of protein kinase D2 in platelets.

Bhavanasi D, Kim S, Goldfinger LE, Kunapuli SP.

Biochem Pharmacol. 2011 Oct 1;82(7):720-7. doi: 10.1016/j.bcp.2011.06.032. Epub 2011 Jun 28.

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