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Items: 1 to 20 of 59

1.

Interaction of sirolimus and everolimus with hepatic and intestinal organic anion-transporting polypeptide transporters.

Picard N, Levoir L, Lamoureux F, Yee SW, Giacomini KM, Marquet P.

Xenobiotica. 2011 Sep;41(9):752-7. doi: 10.3109/00498254.2011.573882. Epub 2011 Apr 27.

PMID:
21524191
2.
3.

Digoxin is not a substrate for organic anion-transporting polypeptide transporters OATP1A2, OATP1B1, OATP1B3, and OATP2B1 but is a substrate for a sodium-dependent transporter expressed in HEK293 cells.

Taub ME, Mease K, Sane RS, Watson CA, Chen L, Ellens H, Hirakawa B, Reyner EL, Jani M, Lee CA.

Drug Metab Dispos. 2011 Nov;39(11):2093-102. doi: 10.1124/dmd.111.040816. Epub 2011 Aug 17.

4.

Contribution of OATP (organic anion-transporting polypeptide) family transporters to the hepatic uptake of fexofenadine in humans.

Shimizu M, Fuse K, Okudaira K, Nishigaki R, Maeda K, Kusuhara H, Sugiyama Y.

Drug Metab Dispos. 2005 Oct;33(10):1477-81. Epub 2005 Jul 13.

5.

The role of organic anion-transporting polypeptides and their common genetic variants in mycophenolic acid pharmacokinetics.

Picard N, Yee SW, Woillard JB, Lebranchu Y, Le Meur Y, Giacomini KM, Marquet P.

Clin Pharmacol Ther. 2010 Jan;87(1):100-8. doi: 10.1038/clpt.2009.205. Epub 2009 Nov 4.

6.

Organic anion transporting polypeptide (OATP)-mediated transport of coproporphyrins I and III.

Bednarczyk D, Boiselle C.

Xenobiotica. 2016;46(5):457-66. doi: 10.3109/00498254.2015.1085111. Epub 2015 Sep 18.

PMID:
26383540
7.

In vivo disposition of doxorubicin is affected by mouse Oatp1a/1b and human OATP1A/1B transporters.

Durmus S, Naik J, Buil L, Wagenaar E, van Tellingen O, Schinkel AH.

Int J Cancer. 2014 Oct 1;135(7):1700-10. doi: 10.1002/ijc.28797. Epub 2014 Mar 4.

8.

Interactions of green tea catechins with organic anion-transporting polypeptides.

Roth M, Timmermann BN, Hagenbuch B.

Drug Metab Dispos. 2011 May;39(5):920-6. doi: 10.1124/dmd.110.036640. Epub 2011 Jan 28.

9.

Cyclosporine inhibition of hepatic and intestinal CYP3A4, uptake and efflux transporters: application of PBPK modeling in the assessment of drug-drug interaction potential.

Gertz M, Cartwright CM, Hobbs MJ, Kenworthy KE, Rowland M, Houston JB, Galetin A.

Pharm Res. 2013 Mar;30(3):761-80. doi: 10.1007/s11095-012-0918-y. Epub 2012 Nov 22.

PMID:
23179780
10.

Pharmaceutical excipients influence the function of human uptake transporting proteins.

Engel A, Oswald S, Siegmund W, Keiser M.

Mol Pharm. 2012 Sep 4;9(9):2577-81. doi: 10.1021/mp3001815. Epub 2012 Aug 1.

PMID:
22808947
11.

Long-lasting inhibitory effects of cyclosporin A, but not tacrolimus, on OATP1B1- and OATP1B3-mediated uptake.

Shitara Y, Takeuchi K, Nagamatsu Y, Wada S, Sugiyama Y, Horie T.

Drug Metab Pharmacokinet. 2012;27(4):368-78. Epub 2012 Jan 13.

12.

Interaction of silymarin flavonolignans with organic anion-transporting polypeptides.

Köck K, Xie Y, Hawke RL, Oberlies NH, Brouwer KL.

Drug Metab Dispos. 2013 May;41(5):958-65. doi: 10.1124/dmd.112.048272. Epub 2013 Feb 11.

13.

Interaction of macrolide antibiotics with intestinally expressed human and rat organic anion-transporting polypeptides.

Lan T, Rao A, Haywood J, Davis CB, Han C, Garver E, Dawson PA.

Drug Metab Dispos. 2009 Dec;37(12):2375-82. doi: 10.1124/dmd.109.028522. Epub 2009 Sep 9.

14.

Mechanism of polybrominated diphenyl ether uptake into the liver: PBDE congeners are substrates of human hepatic OATP transporters.

Pacyniak E, Roth M, Hagenbuch B, Guo GL.

Toxicol Sci. 2010 Jun;115(2):344-53. doi: 10.1093/toxsci/kfq059. Epub 2010 Feb 22.

15.

Organic anion-transporting polypeptides contribute to the hepatic uptake of berberine.

Chen C, Wu ZT, Ma LL, Ni X, Lin YF, Wang L, Chen KP, Huang CG, Pan G.

Xenobiotica. 2015;45(12):1138-46. doi: 10.3109/00498254.2015.1042537. Epub 2015 Jun 11.

PMID:
26068524
16.

Interaction of HIV protease inhibitors with OATP1B1, 1B3, and 2B1.

Annaert P, Ye ZW, Stieger B, Augustijns P.

Xenobiotica. 2010 Mar;40(3):163-76. doi: 10.3109/00498250903509375.

PMID:
20102298
17.

The organic anion transport polypeptide 1d1 (Oatp1d1) mediates hepatocellular uptake of phalloidin and microcystin into skate liver.

Meier-Abt F, Hammann-Hänni A, Stieger B, Ballatori N, Boyer JL.

Toxicol Appl Pharmacol. 2007 Feb 1;218(3):274-9. Epub 2006 Nov 21.

PMID:
17198718
18.

Disposition of ezetimibe is influenced by polymorphisms of the hepatic uptake carrier OATP1B1.

Oswald S, König J, Lütjohann D, Giessmann T, Kroemer HK, Rimmbach C, Rosskopf D, Fromm MF, Siegmund W.

Pharmacogenet Genomics. 2008 Jul;18(7):559-68. doi: 10.1097/FPC.0b013e3282fe9a2c.

PMID:
18551036
19.

Human OATP1B1, OATP1B3 and OATP1A2 can mediate the in vivo uptake and clearance of docetaxel.

Iusuf D, Hendrikx JJ, van Esch A, van de Steeg E, Wagenaar E, Rosing H, Beijnen JH, Schinkel AH.

Int J Cancer. 2015 Jan 1;136(1):225-33. doi: 10.1002/ijc.28970. Epub 2014 Jun 3.

20.

Involvement of mitogen-activated protein kinase signaling pathways in microcystin-LR-induced apoptosis after its selective uptake mediated by OATP1B1 and OATP1B3.

Komatsu M, Furukawa T, Ikeda R, Takumi S, Nong Q, Aoyama K, Akiyama S, Keppler D, Takeuchi T.

Toxicol Sci. 2007 Jun;97(2):407-16. Epub 2007 Mar 16.

PMID:
17369605

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