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Items: 1 to 20 of 47

1.

Protection from diabetes development by single-chain antibody-mediated delivery of a NF-κB inhibitor specifically to β-cells in vivo.

Ueberberg S, Deutschbein T, Klein HH, Dietrich JW, Akinturk S, Prochnow N, Schirrmacher R, Schneider S.

Am J Physiol Endocrinol Metab. 2011 Jul;301(1):E83-90. doi: 10.1152/ajpendo.00603.2010. Epub 2011 Apr 26.

2.

The ToI-beta transgenic mouse: a model to study the specific role of NF-kappaB in beta-cells.

Eldor R, Baum K, Abel R, Sever D, Melloul D.

Diabetes Res Clin Pract. 2009 Dec;86 Suppl 1:S7-14. doi: 10.1016/S0168-8227(09)70003-8.

PMID:
20115936
3.

Radix clematidis extract protects against cytokine- and streptozotocin-induced beta-cell damage by suppressing the NF-kappaB pathway.

Kim EK, Song MY, Hwang TO, Kim HJ, Moon WS, Ryu DG, So HS, Park R, Park JW, Kwon KB, Park BH.

Int J Mol Med. 2008 Sep;22(3):349-56.

PMID:
18698494
4.

Conditional and specific NF-kappaB blockade protects pancreatic beta cells from diabetogenic agents.

Eldor R, Yeffet A, Baum K, Doviner V, Amar D, Ben-Neriah Y, Christofori G, Peled A, Carel JC, Boitard C, Klein T, Serup P, Eizirik DL, Melloul D.

Proc Natl Acad Sci U S A. 2006 Mar 28;103(13):5072-7. Epub 2006 Mar 21.

5.

Role of NF-kappaB in beta-cell death.

Melloul D.

Biochem Soc Trans. 2008 Jun;36(Pt 3):334-9. doi: 10.1042/BST0360334. Review.

PMID:
18481952
6.

Beneficial effect of Flos magnoliae extract on multiple low dose streptozotocin-induced type 1 diabetes development and cytokine-induced beta-cell damage.

Kim EK, Song MY, Kim IS, Moon WS, Ryu DG, So HS, Park R, Park JW, Kwon KB, Park BH.

Int J Mol Med. 2008 Oct;22(4):481-8.

PMID:
18813855
7.

Fructus Xanthii extract protects against cytokine-induced damage in pancreatic beta-cells through suppression of NF-kappaB activation.

Song MY, Kim EK, Lee HJ, Park JW, Ryu DG, Kwon KB, Park BH.

Int J Mol Med. 2009 Apr;23(4):547-53.

PMID:
19288032
9.

Selective inhibition of NF-kappaB in dendritic cells by the NEMO-binding domain peptide blocks maturation and prevents T cell proliferation and polarization.

Tas SW, de Jong EC, Hajji N, May MJ, Ghosh S, Vervoordeldonk MJ, Tak PP.

Eur J Immunol. 2005 Apr;35(4):1164-74.

10.

Radix asari extract protects pancreatic beta cells against cytokine-induced toxicity: implication of the NF-kappaB-iNOS signaling cascade.

Song MY, Kim KA, Lee SY, Kim EK, Lv N, Lee JH, Park JW, Ryu DG, Kwon KB, Park BH.

Int J Mol Med. 2007 Nov;20(5):769-75.

PMID:
17912472
11.

A biphasic role of nuclear transcription factor (NF)-kappaB in the islet beta-cell apoptosis induced by interleukin (IL)-1beta.

Papaccio G, Graziano A, D'Aquino R, Valiante S, Naro F.

J Cell Physiol. 2005 Jul;204(1):124-30.

PMID:
15622524
12.

In silico identification of NF-kappaB-regulated genes in pancreatic beta-cells.

Naamane N, van Helden J, Eizirik DL.

BMC Bioinformatics. 2007 Feb 15;8:55.

13.

Generation of novel single-chain antibodies by phage-display technology to direct imaging agents highly selective to pancreatic beta- or alpha-cells in vivo.

Ueberberg S, Meier JJ, Waengler C, Schechinger W, Dietrich JW, Tannapfel A, Schmitz I, Schirrmacher R, Köller M, Klein HH, Schneider S.

Diabetes. 2009 Oct;58(10):2324-34. doi: 10.2337/db09-0658. Epub 2009 Jul 10.

14.

Protection of NIT-1 pancreatic beta-cells from immune attack by inhibition of NF-kappaB.

Stephens LA, Thomas HE, Kay TW.

J Autoimmun. 1997 Jun;10(3):293-8.

PMID:
9218757
15.

NO-mediated cytotoxicity contributes to multiple low-dose streptozotocin-induced diabetes but not to NOD diabetes.

Yasuda H, Jin Z, Nakayama M, Yamada K, Kishi M, Okumachi Y, Arai T, Moriyama H, Yokono K, Nagata M.

Diabetes Res Clin Pract. 2009 Feb;83(2):200-7. doi: 10.1016/j.diabres.2008.11.029. Epub 2008 Dec 30.

PMID:
19117633
16.

Dihydroavenanthramide D protects pancreatic beta-cells from cytokine and streptozotocin toxicity.

Lv N, Song MY, Lee YR, Choi HN, Kwon KB, Park JW, Park BH.

Biochem Biophys Res Commun. 2009 Sep 11;387(1):97-102. doi: 10.1016/j.bbrc.2009.06.133. Epub 2009 Jul 1.

PMID:
19576175
17.

Effects of DHMEQ, a novel nuclear factor-kappab inhibitor, on beta cell dysfunction in INS-1 cells.

Saisho Y, Hirose H, Horimai C, Miyashita K, Takei I, Umezawa K, Itoh H.

Endocr J. 2008 May;55(2):433-8. Epub 2008 Apr 2.

18.

Pancreatic islet-specific overexpression of Reg3β protein induced the expression of pro-islet genes and protected the mice against streptozotocin-induced diabetes mellitus.

Xiong X, Wang X, Li B, Chowdhury S, Lu Y, Srikant CB, Ning G, Liu JL.

Am J Physiol Endocrinol Metab. 2011 Apr;300(4):E669-80. doi: 10.1152/ajpendo.00600.2010. Epub 2011 Jan 18.

19.

Beta-cell function and mass in type 2 diabetes.

Larsen MO.

Dan Med Bull. 2009 Aug;56(3):153-64.

PMID:
19728971
20.

Newly weaned nonobese diabetic mice show heightened early diabetes sensitivity to multiple low doses of streptozotocin than nondiabetes-prone CD-1 mice: initial beta-cell damage a key trigger for type 1 diabetes?

Reddy S, Elliott RB, Chang M, Hsu T, Rodrigues JA, Qiao L, Robinson E.

Pancreas. 2008 Jul;37(1):e8-e19. doi: 10.1097/MPA.0b013e3181661b1b.

PMID:
18580436

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