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Items: 1 to 20 of 137

1.

Replication and extension of association between common genetic variants in SIM1 and human adiposity.

Swarbrick MM, Evans DS, Valle MI, Favre H, Wu SH, Njajou OT, Li R, Zmuda JM, Miljkovic I, Harris TB, Kwok PY, Vaisse C, Hsueh WC.

Obesity (Silver Spring). 2011 Dec;19(12):2394-403. doi: 10.1038/oby.2011.79. Epub 2011 Apr 21.

2.

Common variation in SIM1 is reproducibly associated with BMI in Pima Indians.

Traurig M, Mack J, Hanson RL, Ghoussaini M, Meyre D, Knowler WC, Kobes S, Froguel P, Bogardus C, Baier LJ.

Diabetes. 2009 Jul;58(7):1682-9. doi: 10.2337/db09-0028. Epub 2009 Apr 28.

3.

Studies of the SIM1 gene in relation to human obesity and obesity-related traits.

Hung CC, Luan J, Sims M, Keogh JM, Hall C, Wareham NJ, O'Rahilly S, Farooqi IS.

Int J Obes (Lond). 2007 Mar;31(3):429-34. Epub 2006 Aug 22.

PMID:
16924270
4.

Analysis of the SIM1 contribution to polygenic obesity in the French population.

Ghoussaini M, Stutzmann F, Couturier C, Vatin V, Durand E, Lecoeur C, Degraeve F, Heude B, Tauber M, Hercberg S, Levy-Marchal C, Tounian P, Weill J, Traurig M, Bogardus C, Baier LJ, Michaud JL, Froguel P, Meyre D.

Obesity (Silver Spring). 2010 Aug;18(8):1670-5. doi: 10.1038/oby.2009.468. Epub 2010 Jan 14.

5.

Characterization of human variants in obesity-related SIM1 protein identifies a hot-spot for dimerization with the partner protein ARNT2.

Sullivan AE, Raimondo A, Schwab TA, Bruning JB, Froguel P, Farooqi IS, Peet DJ, Whitelaw ML.

Biochem J. 2014 Aug 1;461(3):403-12. doi: 10.1042/BJ20131618.

PMID:
24814368
6.

Rare variants in single-minded 1 (SIM1) are associated with severe obesity.

Ramachandrappa S, Raimondo A, Cali AM, Keogh JM, Henning E, Saeed S, Thompson A, Garg S, Bochukova EG, Brage S, Trowse V, Wheeler E, Sullivan AE, Dattani M, Clayton PE, Datta V, Bruning JB, Wareham NJ, O'Rahilly S, Peet DJ, Barroso I, Whitelaw ML, Farooqi IS.

J Clin Invest. 2013 Jul;123(7):3042-50. doi: 10.1172/JCI68016. Epub 2013 Jun 17. Erratum in: J Clin Invest. 2013 Aug 1;123(8):3635. Datta, Vippan [corrected to Datta, Vipan].

7.

Mutation screen of the SIM1 gene in pediatric patients with early-onset obesity.

Zegers D, Beckers S, Hendrickx R, Van Camp JK, de Craemer V, Verrijken A, Van Hoorenbeeck K, Verhulst SL, Rooman RP, Desager KN, Massa G, Van Gaal LF, Van Hul W.

Int J Obes (Lond). 2014 Jul;38(7):1000-4. doi: 10.1038/ijo.2013.188. Epub 2013 Oct 7.

PMID:
24097297
8.

Effects of beta2-adrenergic receptor gene variants on adiposity: the HERITAGE Family Study.

Garenc C, Pérusse L, Chagnon YC, Rankinen T, Gagnon J, Borecki IB, Leon AS, Skinner JS, Wilmore JH, Rao DC, Bouchard C; HERITAGE Family Study.

Obes Res. 2003 May;11(5):612-8.

9.

Analysis of FTO gene variants with obesity and glucose homeostasis measures in the multiethnic Insulin Resistance Atherosclerosis Study cohort.

Wing MR, Ziegler JM, Langefeld CD, Roh BH, Palmer ND, Mayer-Davis EJ, Rewers MJ, Haffner SM, Wagenknecht LE, Bowden DW.

Int J Obes (Lond). 2011 Sep;35(9):1173-82. doi: 10.1038/ijo.2010.244. Epub 2010 Nov 23.

10.

Lifestyle and socioeconomic-status modify the effects of ADRB2 and NOS3 on adiposity in European-American and African-American adolescents.

Lagou V, Liu G, Zhu H, Stallmann-Jorgensen IS, Gutin B, Dong Y, Snieder H.

Obesity (Silver Spring). 2011 Mar;19(3):595-603. doi: 10.1038/oby.2010.224. Epub 2010 Oct 7.

11.

Functional characterization of SIM1-associated enhancers.

Kim MJ, Oksenberg N, Hoffmann TJ, Vaisse C, Ahituv N.

Hum Mol Genet. 2014 Apr 1;23(7):1700-8. doi: 10.1093/hmg/ddt559. Epub 2013 Nov 7.

12.
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14.

Patterns of association between PPARgamma genetic variation and indices of adiposity and insulin action in African-Americans and whites: the CARDIA Study.

Wei Q, Jacobs DR Jr, Schreiner PJ, Siscovick DS, Steffes MW, Fornage M.

J Mol Med (Berl). 2006 Nov;84(11):955-65. Epub 2006 Sep 6.

PMID:
16955276
15.

SIM1 overexpression partially rescues agouti yellow and diet-induced obesity by normalizing food intake.

Kublaoui BM, Holder JL Jr, Tolson KP, Gemelli T, Zinn AR.

Endocrinology. 2006 Oct;147(10):4542-9. Epub 2006 May 18.

PMID:
16709610
16.
17.

Profound obesity associated with a balanced translocation that disrupts the SIM1 gene.

Holder JL Jr, Butte NF, Zinn AR.

Hum Mol Genet. 2000 Jan 1;9(1):101-8.

PMID:
10587584
18.

Association between the 4 bp proinsulin gene insertion polymorphism (IVS-69) and body composition in black South African women.

Berman P, Collins M, Baumgarten I, Seoighe C, Jennings CL, Joffe Y, Lambert EV, Levitt NS, Faulenbach MV, Kahn SE, Goedecke JH.

Obesity (Silver Spring). 2009 Jun;17(6):1298-300. doi: 10.1038/oby.2009.40. Epub 2009 Feb 26.

19.

ARNT2 acts as the dimerization partner of SIM1 for the development of the hypothalamus.

Michaud JL, DeRossi C, May NR, Holdener BC, Fan CM.

Mech Dev. 2000 Feb;90(2):253-61.

20.

Discovery and fine-mapping of adiposity loci using high density imputation of genome-wide association studies in individuals of African ancestry: African Ancestry Anthropometry Genetics Consortium.

Ng MCY, Graff M, Lu Y, Justice AE, Mudgal P, Liu CT, Young K, Yanek LR, Feitosa MF, Wojczynski MK, Rand K, Brody JA, Cade BE, Dimitrov L, Duan Q, Guo X, Lange LA, Nalls MA, Okut H, Tajuddin SM, Tayo BO, Vedantam S, Bradfield JP, Chen G, Chen WM, Chesi A, Irvin MR, Padhukasahasram B, Smith JA, Zheng W, Allison MA, Ambrosone CB, Bandera EV, Bartz TM, Berndt SI, Bernstein L, Blot WJ, Bottinger EP, Carpten J, Chanock SJ, Chen YI, Conti DV, Cooper RS, Fornage M, Freedman BI, Garcia M, Goodman PJ, Hsu YH, Hu J, Huff CD, Ingles SA, John EM, Kittles R, Klein E, Li J, McKnight B, Nayak U, Nemesure B, Ogunniyi A, Olshan A, Press MF, Rohde R, Rybicki BA, Salako B, Sanderson M, Shao Y, Siscovick DS, Stanford JL, Stevens VL, Stram A, Strom SS, Vaidya D, Witte JS, Yao J, Zhu X, Ziegler RG, Zonderman AB, Adeyemo A, Ambs S, Cushman M, Faul JD, Hakonarson H, Levin AM, Nathanson KL, Ware EB, Weir DR, Zhao W, Zhi D; Bone Mineral Density in Childhood Study (BMDCS) Group, Arnett DK, Grant SFA, Kardia SLR, Oloapde OI, Rao DC, Rotimi CN, Sale MM, Williams LK, Zemel BS, Becker DM, Borecki IB, Evans MK, Harris TB, Hirschhorn JN, Li Y, Patel SR, Psaty BM, Rotter JI, Wilson JG, Bowden DW, Cupples LA, Haiman CA, Loos RJF, North KE.

PLoS Genet. 2017 Apr 21;13(4):e1006719. doi: 10.1371/journal.pgen.1006719. eCollection 2017 Apr.

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