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Items: 1 to 20 of 102

1.

Yeast SREBP cleavage activation requires the Golgi Dsc E3 ligase complex.

Stewart EV, Nwosu CC, Tong Z, Roguev A, Cummins TD, Kim DU, Hayles J, Park HO, Hoe KL, Powell DW, Krogan NJ, Espenshade PJ.

Mol Cell. 2011 Apr 22;42(2):160-71. doi: 10.1016/j.molcel.2011.02.035.

2.

Subunit architecture of the Golgi Dsc E3 ligase required for sterol regulatory element-binding protein (SREBP) cleavage in fission yeast.

Lloyd SJ, Raychaudhuri S, Espenshade PJ.

J Biol Chem. 2013 Jul 19;288(29):21043-54. doi: 10.1074/jbc.M113.468215. Epub 2013 Jun 12.

3.

Endoplasmic Reticulum Exit of Golgi-resident Defective for SREBP Cleavage (Dsc) E3 Ligase Complex Requires Its Activity.

Raychaudhuri S, Espenshade PJ.

J Biol Chem. 2015 Jun 5;290(23):14430-40. doi: 10.1074/jbc.M114.630863. Epub 2015 Apr 27.

4.

Yeast sterol regulatory element-binding protein (SREBP) cleavage requires Cdc48 and Dsc5, a ubiquitin regulatory X domain-containing subunit of the Golgi Dsc E3 ligase.

Stewart EV, Lloyd SJ, Burg JS, Nwosu CC, Lintner RE, Daza R, Russ C, Ponchner K, Nusbaum C, Espenshade PJ.

J Biol Chem. 2012 Jan 2;287(1):672-81. doi: 10.1074/jbc.M111.317370. Epub 2011 Nov 15.

5.

Structural requirements for sterol regulatory element-binding protein (SREBP) cleavage in fission yeast.

Cheung R, Espenshade PJ.

J Biol Chem. 2013 Jul 12;288(28):20351-60. doi: 10.1074/jbc.M113.482224. Epub 2013 May 31.

6.

Degradation of sterol regulatory element-binding protein precursor requires the endoplasmic reticulum-associated degradation components Ubc7 and Hrd1 in fission yeast.

Hughes BT, Nwosu CC, Espenshade PJ.

J Biol Chem. 2009 Jul 31;284(31):20512-21. doi: 10.1074/jbc.M109.002436. Epub 2009 Jun 11.

7.

Identification of candidate substrates for the Golgi Tul1 E3 ligase using quantitative diGly proteomics in yeast.

Tong Z, Kim MS, Pandey A, Espenshade PJ.

Mol Cell Proteomics. 2014 Nov;13(11):2871-82. doi: 10.1074/mcp.M114.040774. Epub 2014 Jul 30.

8.

Identification of Rbd2 as a candidate protease for sterol regulatory element binding protein (SREBP) cleavage in fission yeast.

Kim J, Ha HJ, Kim S, Choi AR, Lee SJ, Hoe KL, Kim DU.

Biochem Biophys Res Commun. 2015 Dec 25;468(4):606-10. doi: 10.1016/j.bbrc.2015.10.165. Epub 2015 Nov 3.

PMID:
26545776
9.
10.

Casein kinase 1 regulates sterol regulatory element-binding protein (SREBP) to control sterol homeostasis.

Brookheart RT, Lee CY, Espenshade PJ.

J Biol Chem. 2014 Jan 31;289(5):2725-35. doi: 10.1074/jbc.M113.511899. Epub 2013 Dec 10.

11.

Coordinate Regulation of Yeast Sterol Regulatory Element-binding Protein (SREBP) and Mga2 Transcription Factors.

Burr R, Stewart EV, Espenshade PJ.

J Biol Chem. 2017 Mar 31;292(13):5311-5324. doi: 10.1074/jbc.M117.778209. Epub 2017 Feb 15.

PMID:
28202541
12.

Nuclear protein quality is regulated by the ubiquitin-proteasome system through the activity of Ubc4 and San1 in fission yeast.

Matsuo Y, Kishimoto H, Tanae K, Kitamura K, Katayama S, Kawamukai M.

J Biol Chem. 2011 Apr 15;286(15):13775-90. doi: 10.1074/jbc.M110.169953. Epub 2011 Feb 15.

13.

COPI-mediated retrieval of SCAP is crucial for regulating lipogenesis under basal and sterol-deficient conditions.

Takashima K, Saitoh A, Funabashi T, Hirose S, Yagi C, Nozaki S, Sato R, Shin HW, Nakayama K.

J Cell Sci. 2015 Aug 1;128(15):2805-15. doi: 10.1242/jcs.164137. Epub 2015 Jun 19.

14.

Spatial separation of Golgi and ER during mitosis protects SREBP from unregulated activation.

Bartz R, Sun LP, Bisel B, Wei JH, Seemann J.

EMBO J. 2008 Apr 9;27(7):948-55. doi: 10.1038/emboj.2008.36. Epub 2008 Mar 6.

15.

Mitotic regulation of SREBP and ATF6 by separation of the Golgi and ER.

Bartz R, Seemann J.

Cell Cycle. 2008 Jul 15;7(14):2100-5. Epub 2008 May 22.

PMID:
18635952
16.

Structure of the WD40 domain of SCAP from fission yeast reveals the molecular basis for SREBP recognition.

Gong X, Li J, Shao W, Wu J, Qian H, Ren R, Espenshade P, Yan N.

Cell Res. 2015 Apr;25(4):401-11. doi: 10.1038/cr.2015.32. Epub 2015 Mar 13.

17.

Sterol regulatory element-binding protein (SREBP) cleavage regulates Golgi-to-endoplasmic reticulum recycling of SREBP cleavage-activating protein (SCAP).

Shao W, Espenshade PJ.

J Biol Chem. 2014 Mar 14;289(11):7547-57. doi: 10.1074/jbc.M113.545699. Epub 2014 Jan 29.

18.

A serine protease inhibitor prevents endoplasmic reticulum stress-induced cleavage but not transport of the membrane-bound transcription factor ATF6.

Okada T, Haze K, Nadanaka S, Yoshida H, Seidah NG, Hirano Y, Sato R, Negishi M, Mori K.

J Biol Chem. 2003 Aug 15;278(33):31024-32. Epub 2003 Jun 2.

19.

A Golgi rhomboid protease Rbd2 recruits Cdc48 to cleave yeast SREBP.

Hwang J, Ribbens D, Raychaudhuri S, Cairns L, Gu H, Frost A, Urban S, Espenshade PJ.

EMBO J. 2016 Nov 2;35(21):2332-2349. Epub 2016 Sep 21.

PMID:
27655872
20.

Sterols regulate cycling of SREBP cleavage-activating protein (SCAP) between endoplasmic reticulum and Golgi.

Nohturfft A, DeBose-Boyd RA, Scheek S, Goldstein JL, Brown MS.

Proc Natl Acad Sci U S A. 1999 Sep 28;96(20):11235-40.

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