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Items: 1 to 20 of 200

1.

Histone demethylase JMJD2B coordinates H3K4/H3K9 methylation and promotes hormonally responsive breast carcinogenesis.

Shi L, Sun L, Li Q, Liang J, Yu W, Yi X, Yang X, Li Y, Han X, Zhang Y, Xuan C, Yao Z, Shang Y.

Proc Natl Acad Sci U S A. 2011 May 3;108(18):7541-6. doi: 10.1073/pnas.1017374108.

2.

The histone demethylase JMJD2B plays an essential role in human carcinogenesis through positive regulation of cyclin-dependent kinase 6.

Toyokawa G, Cho HS, Iwai Y, Yoshimatsu M, Takawa M, Hayami S, Maejima K, Shimizu N, Tanaka H, Tsunoda T, Field HI, Kelly JD, Neal DE, Ponder BA, Maehara Y, Nakamura Y, Hamamoto R.

Cancer Prev Res (Phila). 2011 Dec;4(12):2051-61. doi: 10.1158/1940-6207.CAPR-11-0290.

3.

Lid2 is required for coordinating H3K4 and H3K9 methylation of heterochromatin and euchromatin.

Li F, Huarte M, Zaratiegui M, Vaughn MW, Shi Y, Martienssen R, Cande WZ.

Cell. 2008 Oct 17;135(2):272-83. doi: 10.1016/j.cell.2008.08.036.

4.

Regulation of estrogen receptor α by histone methyltransferase SMYD2-mediated protein methylation.

Zhang X, Tanaka K, Yan J, Li J, Peng D, Jiang Y, Yang Z, Barton MC, Wen H, Shi X.

Proc Natl Acad Sci U S A. 2013 Oct 22;110(43):17284-9. doi: 10.1073/pnas.1307959110.

5.

An epigenetic role for PRL-3 as a regulator of H3K9 methylation in colorectal cancer.

Liu Y, Zheng P, Liu Y, Ji T, Liu X, Yao S, Cheng X, Li Y, Chen L, Xiao Z, Zhou J, Li J.

Gut. 2013 Apr;62(4):571-81. doi: 10.1136/gutjnl-2011-301059.

PMID:
22345654
6.

Triptolide induces cell-cycle arrest and apoptosis of human multiple myeloma cells in vitro via altering expression of histone demethylase LSD1 and JMJD2B.

Wen L, Chen Y, Zeng LL, Zhao F, Li R, Liu Y, Zhang C.

Acta Pharmacol Sin. 2012 Jan;33(1):109-19. doi: 10.1038/aps.2011.145.

7.

miR-491-5p functions as a tumor suppressor by targeting JMJD2B in ERα-positive breast cancer.

Hui Z, Yiling C, Wenting Y, XuQun H, ChuanYi Z, Hui L.

FEBS Lett. 2015 Mar 24;589(7):812-21. doi: 10.1016/j.febslet.2015.02.014.

8.

Cooperative demethylation by JMJD2C and LSD1 promotes androgen receptor-dependent gene expression.

Wissmann M, Yin N, Müller JM, Greschik H, Fodor BD, Jenuwein T, Vogler C, Schneider R, Günther T, Buettner R, Metzger E, Schüle R.

Nat Cell Biol. 2007 Mar;9(3):347-53.

PMID:
17277772
9.

Jmjd2b antagonizes H3K9 trimethylation at pericentric heterochromatin in mammalian cells.

Fodor BD, Kubicek S, Yonezawa M, O'Sullivan RJ, Sengupta R, Perez-Burgos L, Opravil S, Mechtler K, Schotta G, Jenuwein T.

Genes Dev. 2006 Jun 15;20(12):1557-62.

10.

Interaction of the Jhd2 Histone H3 Lys-4 Demethylase with Chromatin Is Controlled by Histone H2A Surfaces and Restricted by H2B Ubiquitination.

Huang F, Ramakrishnan S, Pokhrel S, Pflueger C, Parnell TJ, Kasten MM, Currie SL, Bhachech N, Horikoshi M, Graves BJ, Cairns BR, Bhaskara S, Chandrasekharan MB.

J Biol Chem. 2015 Nov 27;290(48):28760-77. doi: 10.1074/jbc.M115.693085.

11.

Studies of H3K4me3 demethylation by KDM5B/Jarid1B/PLU1 reveals strong substrate recognition in vitro and identifies 2,4-pyridine-dicarboxylic acid as an in vitro and in cell inhibitor.

Kristensen LH, Nielsen AL, Helgstrand C, Lees M, Cloos P, Kastrup JS, Helin K, Olsen L, Gajhede M.

FEBS J. 2012 Jun;279(11):1905-14. doi: 10.1111/j.1742-4658.2012.08567.x.

12.

The X-linked mental retardation gene SMCX/JARID1C defines a family of histone H3 lysine 4 demethylases.

Iwase S, Lan F, Bayliss P, de la Torre-Ubieta L, Huarte M, Qi HH, Whetstine JR, Bonni A, Roberts TM, Shi Y.

Cell. 2007 Mar 23;128(6):1077-88.

13.

Control of histone H3 lysine 9 (H3K9) methylation state via cooperative two-step demethylation by Jumonji domain containing 1A (JMJD1A) homodimer.

Goda S, Isagawa T, Chikaoka Y, Kawamura T, Aburatani H.

J Biol Chem. 2013 Dec 27;288(52):36948-56. doi: 10.1074/jbc.M113.492595.

14.

Heat shock protein 90 (Hsp90) selectively regulates the stability of KDM4B/JMJD2B histone demethylase.

Ipenberg I, Guttmann-Raviv N, Khoury HP, Kupershmit I, Ayoub N.

J Biol Chem. 2013 May 24;288(21):14681-7. doi: 10.1074/jbc.C113.462770.

15.

On the mechanism of multiple lysine methylation by the human mixed lineage leukemia protein-1 (MLL1) core complex.

Patel A, Dharmarajan V, Vought VE, Cosgrove MS.

J Biol Chem. 2009 Sep 4;284(36):24242-56. doi: 10.1074/jbc.M109.014498.

16.

Histone demethylase JMJD2B functions as a co-factor of estrogen receptor in breast cancer proliferation and mammary gland development.

Kawazu M, Saso K, Tong KI, McQuire T, Goto K, Son DO, Wakeham A, Miyagishi M, Mak TW, Okada H.

PLoS One. 2011 Mar 18;6(3):e17830. doi: 10.1371/journal.pone.0017830.

17.

Structural basis of a histone H3 lysine 4 demethylase required for stem elongation in rice.

Chen Q, Chen X, Wang Q, Zhang F, Lou Z, Zhang Q, Zhou DX.

PLoS Genet. 2013;9(1):e1003239. doi: 10.1371/journal.pgen.1003239.

18.

PELP1 is a reader of histone H3 methylation that facilitates oestrogen receptor-alpha target gene activation by regulating lysine demethylase 1 specificity.

Nair SS, Nair BC, Cortez V, Chakravarty D, Metzger E, Schüle R, Brann DW, Tekmal RR, Vadlamudi RK.

EMBO Rep. 2010 Jun;11(6):438-44. doi: 10.1038/embor.2010.62.

19.

Binding of the JmjC demethylase JARID1B to LSD1/NuRD suppresses angiogenesis and metastasis in breast cancer cells by repressing chemokine CCL14.

Li Q, Shi L, Gui B, Yu W, Wang J, Zhang D, Han X, Yao Z, Shang Y.

Cancer Res. 2011 Nov 1;71(21):6899-908. doi: 10.1158/0008-5472.CAN-11-1523.

20.

JMJD3 is a histone H3K27 demethylase.

Xiang Y, Zhu Z, Han G, Lin H, Xu L, Chen CD.

Cell Res. 2007 Oct;17(10):850-7.

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