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Items: 1 to 20 of 132

1.

Rapid mobilization of hematopoietic progenitors by AMD3100 and catecholamines is mediated by CXCR4-dependent SDF-1 release from bone marrow stromal cells.

Dar A, Schajnovitz A, Lapid K, Kalinkovich A, Itkin T, Ludin A, Kao WM, Battista M, Tesio M, Kollet O, Cohen NN, Margalit R, Buss EC, Baleux F, Oishi S, Fujii N, Larochelle A, Dunbar CE, Broxmeyer HE, Frenette PS, Lapidot T.

Leukemia. 2011 Aug;25(8):1286-1296. doi: 10.1038/leu.2011.62. Epub 2011 Apr 15. Erratum in: Leukemia. 2011 Aug;25(8):1378.

2.

S1P promotes murine progenitor cell egress and mobilization via S1P1-mediated ROS signaling and SDF-1 release.

Golan K, Vagima Y, Ludin A, Itkin T, Cohen-Gur S, Kalinkovich A, Kollet O, Kim C, Schajnovitz A, Ovadya Y, Lapid K, Shivtiel S, Morris AJ, Ratajczak MZ, Lapidot T.

Blood. 2012 Mar 15;119(11):2478-88. doi: 10.1182/blood-2011-06-358614. Epub 2012 Jan 25.

3.

CXCR4-mediated bone marrow progenitor cell maintenance and mobilization are modulated by c-kit activity.

Cheng M, Zhou J, Wu M, Boriboun C, Thorne T, Liu T, Xiang Z, Zeng Q, Tanaka T, Tang YL, Kishore R, Tomasson MH, Miller RJ, Losordo DW, Qin G.

Circ Res. 2010 Oct 29;107(9):1083-93. doi: 10.1161/CIRCRESAHA.110.220970. Epub 2010 Sep 16.

4.

Update on clinical experience with AMD3100, an SDF-1/CXCL12-CXCR4 inhibitor, in mobilization of hematopoietic stem and progenitor cells.

Pusic I, DiPersio JF.

Curr Opin Hematol. 2010 Jul;17(4):319-26. doi: 10.1097/MOH.0b013e328338b7d5. Review.

PMID:
20473162
5.

Effective mobilization of hematopoietic progenitor cells in G-CSF mobilization defective CD26-/- mice through AMD3100-induced disruption of the CXCL12-CXCR4 axis.

Paganessi LA, Walker AL, Tan LL, Holmes I, Rich E, Fung HC, Christopherson KW 2nd.

Exp Hematol. 2011 Mar;39(3):384-90. doi: 10.1016/j.exphem.2010.12.003. Epub 2010 Dec 17.

6.

[The role of stromal cell-derived factor and its receptor-CXCR4 in G-CSF-induced hematopoietic stem cell mobilization].

Jin FY, Qiu LG, Li QC, Meng HX, Wang YF, Yu Z, Li Q, Han JL.

Zhonghua Xue Ye Xue Za Zhi. 2007 Feb;28(2):98-102. Chinese.

PMID:
17650669
7.

Rapid mobilization of murine and human hematopoietic stem and progenitor cells with AMD3100, a CXCR4 antagonist.

Broxmeyer HE, Orschell CM, Clapp DW, Hangoc G, Cooper S, Plett PA, Liles WC, Li X, Graham-Evans B, Campbell TB, Calandra G, Bridger G, Dale DC, Srour EF.

J Exp Med. 2005 Apr 18;201(8):1307-18.

9.

Adult stem cell mobilization enhances intramembranous bone regeneration: a pilot study.

McNulty MA, Virdi AS, Christopherson KW, Sena K, Frank RR, Sumner DR.

Clin Orthop Relat Res. 2012 Sep;470(9):2503-12. doi: 10.1007/s11999-012-2357-9.

10.

Plerixafor (AMD3100) induces prolonged mobilization of acute lymphoblastic leukemia cells and increases the proportion of cycling cells in the blood in mice.

Welschinger R, Liedtke F, Basnett J, Dela Pena A, Juarez JG, Bradstock KF, Bendall LJ.

Exp Hematol. 2013 Mar;41(3):293-302.e1. doi: 10.1016/j.exphem.2012.11.004. Epub 2012 Nov 23.

PMID:
23178377
11.

AMD3100 and CD26 modulate mobilization, engraftment, and survival of hematopoietic stem and progenitor cells mediated by the SDF-1/CXCL12-CXCR4 axis.

Broxmeyer HE, Hangoc G, Cooper S, Campbell T, Ito S, Mantel C.

Ann N Y Acad Sci. 2007 Jun;1106:1-19. Epub 2007 Mar 14.

PMID:
17360804
12.
13.

Insights into the mechanism of enhanced mobilization of hematopoietic progenitor cells and release of CXCL12 by a combination of AMD3100 and aminoglycoside-polyarginine conjugates.

Berchanski A, Kalinkovich A, Ludin A, Lapidot T, Lapidot A.

FEBS J. 2011 Nov;278(21):4150-65. doi: 10.1111/j.1742-4658.2011.08348.x. Epub 2011 Oct 4.

15.

G-CSF induces stem cell mobilization by decreasing bone marrow SDF-1 and up-regulating CXCR4.

Petit I, Szyper-Kravitz M, Nagler A, Lahav M, Peled A, Habler L, Ponomaryov T, Taichman RS, Arenzana-Seisdedos F, Fujii N, Sandbank J, Zipori D, Lapidot T.

Nat Immunol. 2002 Jul;3(7):687-94. Epub 2002 Jun 17. Erratum in: Nat Immunol 2002 Aug;3(8):787.

PMID:
12068293
16.
17.

AMD3100 improves ovariectomy-induced osteoporosis in mice by facilitating mobilization of hematopoietic stem/progenitor cells.

Im JY, Min WK, Park MH, Kim N, Lee JK, Jin HK, Choi JY, Kim SY, Bae JS.

BMB Rep. 2014 Aug;47(8):439-44.

18.

Small molecule Me6TREN mobilizes hematopoietic stem/progenitor cells by activating MMP-9 expression and disrupting SDF-1/CXCR4 axis.

Zhang J, Ren X, Shi W, Wang S, Chen H, Zhang B, Wang Z, Zhou Y, Chen L, Zhang R, Lv Y, Zhou J, Nan X, He L, Yue W, Li Y, Pei X.

Blood. 2014 Jan 16;123(3):428-41. doi: 10.1182/blood-2013-04-498535. Epub 2013 Nov 6.

19.

A critical role of Src family kinase in SDF-1/CXCR4-mediated bone-marrow progenitor cell recruitment to the ischemic heart.

Cheng M, Huang K, Zhou J, Yan D, Tang YL, Zhao TC, Miller RJ, Kishore R, Losordo DW, Qin G.

J Mol Cell Cardiol. 2015 Apr;81:49-53. doi: 10.1016/j.yjmcc.2015.01.024. Epub 2015 Feb 3.

20.

Parathyroid hormone is a DPP-IV inhibitor and increases SDF-1-driven homing of CXCR4(+) stem cells into the ischaemic heart.

Huber BC, Brunner S, Segeth A, Nathan P, Fischer R, Zaruba MM, Vallaster M, Theiss HD, David R, Gerbitz A, Franz WM.

Cardiovasc Res. 2011 Jun 1;90(3):529-37. doi: 10.1093/cvr/cvr014. Epub 2011 Jan 18.

PMID:
21245057

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