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Items: 1 to 20 of 128

1.

Regulation of lipopolysaccharide-induced translation of tumor necrosis factor-alpha by the toll-like receptor 4 adaptor protein TRAM.

Wang L, Trebicka E, Fu Y, Waggoner L, Akira S, Fitzgerald KA, Kagan JC, Cherayil BJ.

J Innate Immun. 2011;3(5):437-46. doi: 10.1159/000324833. Epub 2011 Apr 14.

2.

A role for the adaptor proteins TRAM and TRIF in toll-like receptor 2 signaling.

Nilsen NJ, Vladimer GI, Stenvik J, Orning MP, Zeid-Kilani MV, Bugge M, Bergstroem B, Conlon J, Husebye H, Hise AG, Fitzgerald KA, Espevik T, Lien E.

J Biol Chem. 2015 Feb 6;290(6):3209-22. doi: 10.1074/jbc.M114.593426. Epub 2014 Dec 11.

3.

TRIF signaling stimulates translation of TNF-alpha mRNA via prolonged activation of MK2.

Gais P, Tiedje C, Altmayr F, Gaestel M, Weighardt H, Holzmann B.

J Immunol. 2010 May 15;184(10):5842-8. doi: 10.4049/jimmunol.0902456. Epub 2010 Apr 7.

4.

Toll-like receptor 3 and 4 signalling through the TRIF and TRAM adaptors in haematopoietic cells promotes atherosclerosis.

Lundberg AM, Ketelhuth DF, Johansson ME, Gerdes N, Liu S, Yamamoto M, Akira S, Hansson GK.

Cardiovasc Res. 2013 Jul 15;99(2):364-73. doi: 10.1093/cvr/cvt033. Epub 2013 Feb 14.

PMID:
23417039
5.

TRIF signaling is essential for TLR4-driven IgE class switching.

Janssen E, Ozcan E, Liadaki K, Jabara HH, Manis J, Ullas S, Akira S, Fitzgerald KA, Golenbock DT, Geha RS.

J Immunol. 2014 Mar 15;192(6):2651-8. doi: 10.4049/jimmunol.1300909. Epub 2014 Feb 14.

6.

Inhibition of TLR4 signaling by TRAM-derived decoy peptides in vitro and in vivo.

Piao W, Vogel SN, Toshchakov VY.

J Immunol. 2013 Mar 1;190(5):2263-72. doi: 10.4049/jimmunol.1202703. Epub 2013 Jan 23.

7.

The immunoproteasomes regulate LPS-induced TRIF/TRAM signaling pathway in murine macrophages.

Reis J, Hassan F, Guan XQ, Shen J, Monaco JJ, Papasian CJ, Qureshi AA, Van Way CW 3rd, Vogel SN, Morrison DC, Qureshi N.

Cell Biochem Biophys. 2011 Jun;60(1-2):119-26. doi: 10.1007/s12013-011-9183-7.

9.

Recruitment of TLR adapter TRIF to TLR4 signaling complex is mediated by the second helical region of TRIF TIR domain.

Piao W, Ru LW, Piepenbrink KH, Sundberg EJ, Vogel SN, Toshchakov VY.

Proc Natl Acad Sci U S A. 2013 Nov 19;110(47):19036-41. doi: 10.1073/pnas.1313575110. Epub 2013 Nov 5.

10.

SHP-2 phosphatase negatively regulates the TRIF adaptor protein-dependent type I interferon and proinflammatory cytokine production.

An H, Zhao W, Hou J, Zhang Y, Xie Y, Zheng Y, Xu H, Qian C, Zhou J, Yu Y, Liu S, Feng G, Cao X.

Immunity. 2006 Dec;25(6):919-28. Epub 2006 Dec 7.

11.

Absence of TRIF signaling in lipopolysaccharide-stimulated murine mast cells.

Keck S, Müller I, Fejer G, Savic I, Tchaptchet S, Nielsen PJ, Galanos C, Huber M, Freudenberg MA.

J Immunol. 2011 May 1;186(9):5478-88. doi: 10.4049/jimmunol.1000458. Epub 2011 Mar 25.

12.

Inhibition of clathrin/dynamin-dependent internalization interferes with LPS-mediated TRAM-TRIF-dependent signaling pathway.

Wang Y, Yang Y, Liu X, Wang N, Cao H, Lu Y, Zhou H, Zheng J.

Cell Immunol. 2012;274(1-2):121-9. doi: 10.1016/j.cellimm.2011.12.007. Epub 2012 Jan 2.

PMID:
22341560
13.

Melatonin modulates TLR4-mediated inflammatory genes through MyD88- and TRIF-dependent signaling pathways in lipopolysaccharide-stimulated RAW264.7 cells.

Xia MZ, Liang YL, Wang H, Chen X, Huang YY, Zhang ZH, Chen YH, Zhang C, Zhao M, Xu DX, Song LH.

J Pineal Res. 2012 Nov;53(4):325-34. doi: 10.1111/j.1600-079X.2012.01002.x. Epub 2012 Apr 27.

PMID:
22537289
14.

Salmonella-induced SipB-independent cell death requires Toll-like receptor-4 signalling via the adapter proteins Tram and Trif.

Cook P, Tötemeyer S, Stevenson C, Fitzgerald KA, Yamamoto M, Akira S, Maskell DJ, Bryant CE.

Immunology. 2007 Oct;122(2):222-9. Epub 2007 May 9.

15.

Roles for LPS-dependent interaction and relocation of TLR4 and TRAM in TRIF-signaling.

Tanimura N, Saitoh S, Matsumoto F, Akashi-Takamura S, Miyake K.

Biochem Biophys Res Commun. 2008 Mar 28;368(1):94-9. doi: 10.1016/j.bbrc.2008.01.061. Epub 2008 Jan 28.

PMID:
18222170
16.

The TRIF/TBK1/IRF-3 activation pathway is the primary inhibitory target of resveratrol, contributing to its broad-spectrum anti-inflammatory effects.

Kim MH, Yoo DS, Lee SY, Byeon SE, Lee YG, Min T, Rho HS, Rhee MH, Lee J, Cho JY.

Pharmazie. 2011 Apr;66(4):293-300.

PMID:
21612158
17.

Toll-like receptor 3-elicited MAPK activation induces stabilization of interferon-β mRNA.

Johnsen IB, Nguyen TT, Bergstrøm B, Lien E, Anthonsen MW.

Cytokine. 2012 Mar;57(3):337-46. doi: 10.1016/j.cyto.2011.11.024. Epub 2011 Dec 24.

PMID:
22200507
18.

CD14 dependence of TLR4 endocytosis and TRIF signaling displays ligand specificity and is dissociable in endotoxin tolerance.

Rajaiah R, Perkins DJ, Ireland DD, Vogel SN.

Proc Natl Acad Sci U S A. 2015 Jul 7;112(27):8391-6. doi: 10.1073/pnas.1424980112. Epub 2015 Jun 23.

19.

Innate immune responses to endosymbiotic Wolbachia bacteria in Brugia malayi and Onchocerca volvulus are dependent on TLR2, TLR6, MyD88, and Mal, but not TLR4, TRIF, or TRAM.

Hise AG, Daehnel K, Gillette-Ferguson I, Cho E, McGarry HF, Taylor MJ, Golenbock DT, Fitzgerald KA, Kazura JW, Pearlman E.

J Immunol. 2007 Jan 15;178(2):1068-76.

20.

The TLR signaling adaptor TRAM interacts with TRAF6 to mediate activation of the inflammatory response by TLR4.

Verstak B, Stack J, Ve T, Mangan M, Hjerrild K, Jeon J, Stahl R, Latz E, Gay N, Kobe B, Bowie AG, Mansell A.

J Leukoc Biol. 2014 Sep;96(3):427-36. doi: 10.1189/jlb.2A0913-487R. Epub 2014 May 8.

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