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Items: 1 to 20 of 156

1.

Control of central and peripheral tolerance by Aire.

Metzger TC, Anderson MS.

Immunol Rev. 2011 May;241(1):89-103. doi: 10.1111/j.1600-065X.2011.01008.x. Review.

2.

[Function of Aire in central and peripheral immune tolerance].

Hanafusa T.

Nihon Rinsho Meneki Gakkai Kaishi. 2014;37(3):133-8. Review. Japanese.

3.

Deletional tolerance mediated by extrathymic Aire-expressing cells.

Gardner JM, Devoss JJ, Friedman RS, Wong DJ, Tan YX, Zhou X, Johannes KP, Su MA, Chang HY, Krummel MF, Anderson MS.

Science. 2008 Aug 8;321(5890):843-7. doi: 10.1126/science.1159407.

4.

The role of Aire in clonal selection.

Taniguchi RT, Anderson MS.

Immunol Cell Biol. 2011 Jan;89(1):40-4. doi: 10.1038/icb.2010.132. Epub 2010 Nov 16. Review.

5.

Thymosin α1: burying secrets in the thymus.

Moretti S, Oikonomou V, Garaci E, Romani L.

Expert Opin Biol Ther. 2015;15 Suppl 1:S51-8. doi: 10.1517/14712598.2015.1044895. Epub 2015 Jun 22.

PMID:
26098878
6.

Aire mediates thymic expression and tolerance of pancreatic antigens via an unconventional transcriptional mechanism.

Danso-Abeam D, Staats KA, Franckaert D, Van Den Bosch L, Liston A, Gray DH, Dooley J.

Eur J Immunol. 2013 Jan;43(1):75-84. doi: 10.1002/eji.201242761. Epub 2012 Dec 6.

7.

AIRE in the thymus and beyond.

Gardner JM, Fletcher AL, Anderson MS, Turley SJ.

Curr Opin Immunol. 2009 Dec;21(6):582-9. doi: 10.1016/j.coi.2009.08.007. Epub 2009 Oct 14. Review.

8.

Aire regulates the transfer of antigen from mTECs to dendritic cells for induction of thymic tolerance.

Hubert FX, Kinkel SA, Davey GM, Phipson B, Mueller SN, Liston A, Proietto AI, Cannon PZ, Forehan S, Smyth GK, Wu L, Goodnow CC, Carbone FR, Scott HS, Heath WR.

Blood. 2011 Sep 1;118(9):2462-72. doi: 10.1182/blood-2010-06-286393. Epub 2011 Apr 19.

9.

Gene dosage--limiting role of Aire in thymic expression, clonal deletion, and organ-specific autoimmunity.

Liston A, Gray DH, Lesage S, Fletcher AL, Wilson J, Webster KE, Scott HS, Boyd RL, Peltonen L, Goodnow CC.

J Exp Med. 2004 Oct 18;200(8):1015-26.

10.

Fezf2 Orchestrates a Thymic Program of Self-Antigen Expression for Immune Tolerance.

Takaba H, Morishita Y, Tomofuji Y, Danks L, Nitta T, Komatsu N, Kodama T, Takayanagi H.

Cell. 2015 Nov 5;163(4):975-87. doi: 10.1016/j.cell.2015.10.013.

12.

The cellular mechanism of Aire control of T cell tolerance.

Anderson MS, Venanzi ES, Chen Z, Berzins SP, Benoist C, Mathis D.

Immunity. 2005 Aug;23(2):227-39.

13.

Recent insights into the role and molecular mechanisms of the autoimmune regulator (AIRE) gene in autoimmunity.

Fierabracci A.

Autoimmun Rev. 2011 Jan;10(3):137-43. doi: 10.1016/j.autrev.2010.08.019. Epub 2010 Sep 17. Review.

PMID:
20850570
14.

Identification of a novel cis-regulatory element essential for immune tolerance.

LaFlam TN, Seumois G, Miller CN, Lwin W, Fasano KJ, Waterfield M, Proekt I, Vijayanand P, Anderson MS.

J Exp Med. 2015 Nov 16;212(12):1993-2002. doi: 10.1084/jem.20151069. Epub 2015 Nov 2.

15.

Mouse thymic epithelial cell lines expressing "Aire" and peripheral tissue-specific antigens reproduce in vitro negative selection of T cells.

Yamaguchi Y, Takayanagi A, Chen J, Sakai K, Kudoh J, Shimizu N.

Exp Cell Res. 2011 Aug 15;317(14):2019-30. doi: 10.1016/j.yexcr.2011.05.002. Epub 2011 Jun 15.

PMID:
21683072
16.

Aire-dependent thymic expression of desmoglein 3, the autoantigen in pemphigus vulgaris, and its role in T-cell tolerance.

Wada N, Nishifuji K, Yamada T, Kudoh J, Shimizu N, Matsumoto M, Peltonen L, Nagafuchi S, Amagai M.

J Invest Dermatol. 2011 Feb;131(2):410-7. doi: 10.1038/jid.2010.330. Epub 2010 Nov 4.

17.

Development of autoimmunity against transcriptionally unrepressed target antigen in the thymus of Aire-deficient mice.

Kuroda N, Mitani T, Takeda N, Ishimaru N, Arakaki R, Hayashi Y, Bando Y, Izumi K, Takahashi T, Nomura T, Sakaguchi S, Ueno T, Takahama Y, Uchida D, Sun S, Kajiura F, Mouri Y, Han H, Matsushima A, Yamada G, Matsumoto M.

J Immunol. 2005 Feb 15;174(4):1862-70.

18.

Aire Enforces Immune Tolerance by Directing Autoreactive T Cells into the Regulatory T Cell Lineage.

Malchow S, Leventhal DS, Lee V, Nishi S, Socci ND, Savage PA.

Immunity. 2016 May 17;44(5):1102-13. doi: 10.1016/j.immuni.2016.02.009. Epub 2016 Apr 26.

19.

Alterations of the autoimmune regulator transcription factor and failure of central tolerance: APECED as a model.

Gallo V, Giardino G, Capalbo D, Palamaro L, Romano R, Santamaria F, Maio F, Salerno M, Vajro P, Pignata C.

Expert Rev Clin Immunol. 2013 Jan;9(1):43-51. doi: 10.1586/eci.12.88. Review.

PMID:
23256763
20.

Selection of Foxp3+ regulatory T cells specific for self antigen expressed and presented by Aire+ medullary thymic epithelial cells.

Aschenbrenner K, D'Cruz LM, Vollmann EH, Hinterberger M, Emmerich J, Swee LK, Rolink A, Klein L.

Nat Immunol. 2007 Apr;8(4):351-8. Epub 2007 Feb 25.

PMID:
17322887

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