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Items: 1 to 20 of 112

1.

Impact of recently emerged sterol 14{alpha}-demethylase (CYP51) variants of Mycosphaerella graminicola on azole fungicide sensitivity.

Cools HJ, Mullins JG, Fraaije BA, Parker JE, Kelly DE, Lucas JA, Kelly SL.

Appl Environ Microbiol. 2011 Jun;77(11):3830-7. doi: 10.1128/AEM.00027-11.

2.

Heterologous expression of mutated eburicol 14alpha-demethylase (CYP51) proteins of Mycosphaerella graminicola to assess effects on azole fungicide sensitivity and intrinsic protein function.

Cools HJ, Parker JE, Kelly DE, Lucas JA, Fraaije BA, Kelly SL.

Appl Environ Microbiol. 2010 May;76(9):2866-72. doi: 10.1128/AEM.02158-09.

3.

Overexpression of the sterol 14α-demethylase gene (MgCYP51) in Mycosphaerella graminicola isolates confers a novel azole fungicide sensitivity phenotype.

Cools HJ, Bayon C, Atkins S, Lucas JA, Fraaije BA.

Pest Manag Sci. 2012 Jul;68(7):1034-40. doi: 10.1002/ps.3263.

PMID:
22411894
4.

Update on mechanisms of azole resistance in Mycosphaerella graminicola and implications for future control.

Cools HJ, Fraaije BA.

Pest Manag Sci. 2013 Feb;69(2):150-5. doi: 10.1002/ps.3348. Review.

PMID:
22730104
5.

Mechanism of binding of prothioconazole to Mycosphaerella graminicola CYP51 differs from that of other azole antifungals.

Parker JE, Warrilow AG, Cools HJ, Martel CM, Nes WD, Fraaije BA, Lucas JA, Kelly DE, Kelly SL.

Appl Environ Microbiol. 2011 Feb;77(4):1460-5. doi: 10.1128/AEM.01332-10.

6.

Molecular modelling of the emergence of azole resistance in Mycosphaerella graminicola.

Mullins JG, Parker JE, Cools HJ, Togawa RC, Lucas JA, Fraaije BA, Kelly DE, Kelly SL.

PLoS One. 2011;6(6):e20973. doi: 10.1371/journal.pone.0020973.

7.

Novel Substrate Specificity and Temperature-Sensitive Activity of Mycosphaerella graminicola CYP51 Supported by the Native NADPH Cytochrome P450 Reductase.

Price CL, Warrilow AG, Parker JE, Mullins JG, Nes WD, Kelly DE, Kelly SL.

Appl Environ Microbiol. 2015 May 15;81(10):3379-86. doi: 10.1128/AEM.03965-14.

8.

Sterol content analysis suggests altered eburicol 14alpha-demethylase (CYP51) activity in isolates of Mycosphaerella graminicola adapted to azole fungicides.

Bean TP, Cools HJ, Lucas JA, Hawkins ND, Ward JL, Shaw MW, Fraaije BA.

FEMS Microbiol Lett. 2009 Jun;296(2):266-73. doi: 10.1111/j.1574-6968.2009.01645.x.

9.

Alterations in the predicted regulatory and coding regions of the sterol 14α-demethylase gene (CYP51) confer decreased azole sensitivity in the oilseed rape pathogen Pyrenopeziza brassicae.

Carter HE, Fraaije BA, West JS, Kelly SL, Mehl A, Shaw MW, Cools HJ.

Mol Plant Pathol. 2014 Jun;15(5):513-22. doi: 10.1111/mpp.12106.

PMID:
24298976
10.

Protective and curative efficacy of prothioconazole against isolates of Mycosphaerella graminicola differing in their in vitro sensitivity to DMI fungicides.

Sanssené J, Selim S, Roisin-Fichter C, Djerroud L, Deweer C, Halama P.

Pest Manag Sci. 2011 Sep;67(9):1134-40. doi: 10.1002/ps.2163.

PMID:
21480466
11.

A novel substitution I381V in the sterol 14alpha-demethylase (CYP51) of Mycosphaerella graminicola is differentially selected by azole fungicides.

Fraaije BA, Cools HJ, Kim SH, Motteram J, Clark WS, Lucas JA.

Mol Plant Pathol. 2007 May;8(3):245-54. doi: 10.1111/j.1364-3703.2007.00388.x.

PMID:
20507496
12.
13.

Are azole fungicides losing ground against Septoria wheat disease? Resistance mechanisms in Mycosphaerella graminicola.

Cools HJ, Fraaije BA.

Pest Manag Sci. 2008 Jul;64(7):681-4. doi: 10.1002/ps.1568.

PMID:
18366065
14.

Multiple mechanisms account for variation in base-line sensitivity to azole fungicides in field isolates of Mycosphaerella graminicola.

Stergiopoulos I, van Nistelrooy JG, Kema GH, De Waard MA.

Pest Manag Sci. 2003 Dec;59(12):1333-43.

PMID:
14667055
15.

Expression and homology modelling of sterol 14alpha-demethylase of Magnaporthe grisea and its interaction with azoles.

Yang J, Zhang Q, Liao M, Xiao M, Xiao W, Yang S, Wan J.

Pest Manag Sci. 2009 Mar;65(3):260-5. doi: 10.1002/ps.1680.

PMID:
19152375
16.

QTL mapping of fungicide sensitivity reveals novel genes and pleiotropy with melanization in the pathogen Zymoseptoria tritici.

Lendenmann MH, Croll D, McDonald BA.

Fungal Genet Biol. 2015 Jul;80:53-67. doi: 10.1016/j.fgb.2015.05.001.

PMID:
25979163
17.

The amino acid substitution N136Y in Candida albicans sterol 14alpha-demethylase is involved in fluconazole resistance.

Alvarez-Rueda N, Fleury A, Logé C, Pagniez F, Robert E, Morio F, Le Pape P.

Med Mycol. 2016 Oct 1;54(7):764-75. doi: 10.1093/mmy/myw023.

PMID:
27143634
18.

Characterization of the sterol 14α-demethylases of Fusarium graminearum identifies a novel genus-specific CYP51 function.

Fan J, Urban M, Parker JE, Brewer HC, Kelly SL, Hammond-Kosack KE, Fraaije BA, Liu X, Cools HJ.

New Phytol. 2013 May;198(3):821-35. doi: 10.1111/nph.12193.

19.
20.

Assessment of the cytochrome B substitution G143A in the Algerian population of Mycosphaerella graminicola.

Allioui N, Siah A, Brinis L, Reignault P, Halama P.

Commun Agric Appl Biol Sci. 2013;78(3):613-6.

PMID:
25151839

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