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Germinal center-specific protein human germinal center associated lymphoma directly interacts with both myosin and actin and increases the binding of myosin to actin.

Lu X, Kazmierczak K, Jiang X, Jones M, Watt J, Helfman DM, Moore JR, Szczesna-Cordary D, Lossos IS.

FEBS J. 2011 Jun;278(11):1922-31. doi: 10.1111/j.1742-4658.2011.08109.x. Epub 2011 Apr 20.


miR-155 regulates HGAL expression and increases lymphoma cell motility.

Dagan LN, Jiang X, Bhatt S, Cubedo E, Rajewsky K, Lossos IS.

Blood. 2012 Jan 12;119(2):513-20. doi: 10.1182/blood-2011-08-370536. Epub 2011 Nov 16.


HGAL protein expression persists in disorders of germinal center dissolution: potential role of HGAL in the germinal center microenvironment.

Temmins C, Zhao S, Lossos IS, Natkunam Y.

Appl Immunohistochem Mol Morphol. 2011 May;19(3):266-72. doi: 10.1097/PAI.0b013e3181f89a4d.


Expression of the human germinal center-associated lymphoma (HGAL) protein, a new marker of germinal center B-cell derivation.

Natkunam Y, Lossos IS, Taidi B, Zhao S, Lu X, Ding F, Hammer AS, Marafioti T, Byrne GE Jr, Levy S, Warnke RA, Levy R.

Blood. 2005 May 15;105(10):3979-86. Epub 2005 Jan 27.


Expression of the human germinal center-associated lymphoma (HGAL) protein identifies a subset of classic Hodgkin lymphoma of germinal center derivation and improved survival.

Natkunam Y, Hsi ED, Aoun P, Zhao S, Elson P, Pohlman B, Naushad H, Bast M, Levy R, Lossos IS.

Blood. 2007 Jan 1;109(1):298-305. Epub 2006 Sep 5.


HGAL localization to cell membrane regulates B-cell receptor signaling.

Lu X, Sicard R, Jiang X, Stockus JN, McNamara G, Abdulreda M, Moy VT, Landgraf R, Lossos IS.

Blood. 2015 Jan 22;125(4):649-57. doi: 10.1182/blood-2014-04-571331. Epub 2014 Nov 7.


HGAL, a lymphoma prognostic biomarker, interacts with the cytoskeleton and mediates the effects of IL-6 on cell migration.

Lu X, Chen J, Malumbres R, Cubedo Gil E, Helfman DM, Lossos IS.

Blood. 2007 Dec 15;110(13):4268-77. Epub 2007 Sep 6.


Human germinal center-associated lymphoma protein expression is associated with improved failure-free survival in Brazilian patients with classical Hodgkin lymphoma.

Azambuja D, Lossos IS, Biasoli I, Morais JC, Britto L, Scheliga A, Pulcheri W, Natkunam Y, Spector N.

Leuk Lymphoma. 2009 Nov;50(11):1830-6. doi: 10.3109/10428190903242628.


HGAL, a germinal center specific protein, decreases lymphoma cell motility by modulation of the RhoA signaling pathway.

Jiang X, Lu X, McNamara G, Liu X, Cubedo E, Sarosiek KA, Sánchez-García I, Helfman DM, Lossos IS.

Blood. 2010 Dec 9;116(24):5217-27. doi: 10.1182/blood-2010-04-281568. Epub 2010 Sep 15.


HGAL is a novel interleukin-4-inducible gene that strongly predicts survival in diffuse large B-cell lymphoma.

Lossos IS, Alizadeh AA, Rajapaksa R, Tibshirani R, Levy R.

Blood. 2003 Jan 15;101(2):433-40.


PRDM1/Blimp1 downregulates expression of germinal center genes LMO2 and HGAL.

Cubedo E, Maurin M, Jiang X, Lossos IS, Wright KL.

FEBS J. 2011 Sep;278(17):3065-75. doi: 10.1111/j.1742-4658.2011.08227.x. Epub 2011 Aug 2.


The contribution of HGAL/GCET2 in immunohistological algorithms: a comparative study in 424 cases of nodal diffuse large B-cell lymphoma.

Gualco G, Bacchi LM, Domeny-Duarte P, Natkunam Y, Bacchi CE.

Mod Pathol. 2012 Nov;25(11):1439-45. doi: 10.1038/modpathol.2012.119. Epub 2012 Jun 29.


Diagnostic Utility of the Germinal Center-associated Markers GCET1, HGAL, and LMO2 in Hematolymphoid Neoplasms.

Menter T, Gasser A, Juskevicius D, Dirnhofer S, Tzankov A.

Appl Immunohistochem Mol Morphol. 2015 Aug;23(7):491-8. doi: 10.1097/PAI.0000000000000107.


Expression of the serpin centerin defines a germinal center phenotype in B-cell lymphomas.

Paterson MA, Hosking PS, Coughlin PB.

Am J Clin Pathol. 2008 Jul;130(1):117-26. doi: 10.1309/9QKE68QU7B825A3U.


Comparison of germinal center markers CD10, BCL6 and human germinal center-associated lymphoma (HGAL) in follicular lymphomas.

Goteri G, Lucarini G, Zizzi A, Costagliola A, Giantomassi F, Stramazzotti D, Rubini C, Leoni P.

Diagn Pathol. 2011 Oct 11;6:97. doi: 10.1186/1746-1596-6-97.


Immunoarchitectural patterns in follicular lymphoma: efficacy of HGAL and LMO2 in the detection of the interfollicular and diffuse components.

Younes SF, Beck AH, Lossos IS, Levy R, Warnke RA, Natkunam Y.

Am J Surg Pathol. 2010 Sep;34(9):1266-76. doi: 10.1097/PAS.0b013e3181e9343d.


Jaw1/LRMP, a germinal centre-associated marker for the immunohistological study of B-cell lymphomas.

Tedoldi S, Paterson JC, Cordell J, Tan SY, Jones M, Manek S, Dei Tos AP, Roberton H, Masir N, Natkunam Y, Pileri SA, Facchetti F, Hansmann ML, Mason DY, Marafioti T.

J Pathol. 2006 Aug;209(4):454-63.


Studies of a germinal centre B-cell expressed gene, GCET2, suggest its role as a membrane associated adapter protein.

Pan Z, Shen Y, Ge B, Du C, McKeithan T, Chan WC.

Br J Haematol. 2007 Jun;137(6):578-90. Epub 2007 May 9.


Functional characterization of human myosin-18A and its interaction with F-actin and GOLPH3.

Taft MH, Behrmann E, Munske-Weidemann LC, Thiel C, Raunser S, Manstein DJ.

J Biol Chem. 2013 Oct 18;288(42):30029-41. doi: 10.1074/jbc.M113.497180. Epub 2013 Aug 29.


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