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Items: 1 to 20 of 179

1.

In vitro inhibition of Huanglian [Rhizoma coptidis (L.)] and its six active alkaloids on six cytochrome P450 isoforms in human liver microsomes.

Han YL, Yu HL, Li D, Meng XL, Zhou ZY, Yu Q, Zhang XY, Wang FJ, Guo C.

Phytother Res. 2011 Nov;25(11):1660-5. doi: 10.1002/ptr.3475. Epub 2011 Mar 21.

PMID:
21425377
2.

Anti-Alzheimer and antioxidant activities of Coptidis Rhizoma alkaloids.

Jung HA, Min BS, Yokozawa T, Lee JH, Kim YS, Choi JS.

Biol Pharm Bull. 2009 Aug;32(8):1433-8.

3.

Inhibitory activities of the alkaloids from Coptidis Rhizoma against aldose reductase.

Jung HA, Yoon NY, Bae HJ, Min BS, Choi JS.

Arch Pharm Res. 2008 Nov;31(11):1405-12. doi: 10.1007/s12272-001-2124-z. Epub 2008 Nov 21.

PMID:
19023536
4.

Metabolism of 7-benzyloxy-4-trifluoromethyl-coumarin by human hepatic cytochrome P450 isoforms.

Renwick AB, Surry D, Price RJ, Lake BG, Evans DC.

Xenobiotica. 2000 Oct;30(10):955-69.

PMID:
11315104
5.

In vitro inhibitory effects of Wen-pi-tang-Hab-Wu-ling-san on human cytochrome P450 isoforms.

Lee HW, Kim DW, Phapale PB, Lim MS, Park J, Seo JJ, Park KM, Park YK, Yoon YR.

J Clin Pharm Ther. 2011 Aug;36(4):496-503. doi: 10.1111/j.1365-2710.2010.01201.x. Epub 2010 Aug 24.

PMID:
21729114
6.
7.

Trimethoprim and sulfamethoxazole are selective inhibitors of CYP2C8 and CYP2C9, respectively.

Wen X, Wang JS, Backman JT, Laitila J, Neuvonen PJ.

Drug Metab Dispos. 2002 Jun;30(6):631-5.

8.

Selective inhibition of vascular smooth muscle cell proliferation by coptisine isolated from Coptis rhizoma, one of the crude drugs composing Kampo medicines Unsei-in.

Tanabe H, Suzuki H, Nagatsu A, Mizukami H, Ogihara Y, Inoue M.

Phytomedicine. 2006 May;13(5):334-42. Epub 2005 Sep 23.

PMID:
16635741
9.

Identification of the toxic constituents in Rhizoma Coptidis.

Ma BL, Ma YM, Shi R, Wang TM, Zhang N, Wang CH, Yang Y.

J Ethnopharmacol. 2010 Mar 24;128(2):357-64. doi: 10.1016/j.jep.2010.01.047. Epub 2010 Feb 1.

PMID:
20117200
10.

[Microcalorimetric investigation on the interaction of six alkaloids from rhizoma coptidis].

Li JX, Wang JY, Zhang LL, Yan D, Wang RL, Li BC, Xiao XH.

Yao Xue Xue Bao. 2013 Dec;48(12):1807-11. Chinese.

PMID:
24689238
11.

Identification and characterization of potent CYP2D6 inhibitors in lotus leaves.

Ye LH, He XX, Kong LT, Liao YH, Pan RL, Xiao BX, Liu XM, Chang Q.

J Ethnopharmacol. 2014 Apr 11;153(1):190-6. doi: 10.1016/j.jep.2014.02.014. Epub 2014 Feb 21.

PMID:
24561383
12.

Dynamic monitoring of the cytotoxic effects of protoberberine alkaloids from Rhizoma Coptidis on HepG2 cells using the xCELLigence system.

Zhang LL, Ma LN, Yan D, Zhang CE, Gao D, Xiong Y, Sheng FY, Dong XP, Xiao XH.

Chin J Nat Med. 2014 Jun;12(6):428-35. doi: 10.1016/S1875-5364(14)60067-4.

PMID:
24969523
13.

Safety evaluation of main alkaloids from Rhizoma Coptidis.

Yi J, Ye X, Wang D, He K, Yang Y, Liu X, Li X.

J Ethnopharmacol. 2013 Jan 9;145(1):303-10. doi: 10.1016/j.jep.2012.10.062. Epub 2012 Nov 16.

PMID:
23159469
14.

Protective role of Coptidis Rhizoma alkaloids against peroxynitrite-induced damage to renal tubular epithelial cells.

Yokozawa T, Satoh A, Cho EJ, Kashiwada Y, Ikeshiro Y.

J Pharm Pharmacol. 2005 Mar;57(3):367-74.

PMID:
15807993
15.
16.

Equally potent inhibitors of cholesterol synthesis in human hepatocytes have distinguishable effects on different cytochrome P450 enzymes.

Cohen LH, van Leeuwen RE, van Thiel GC, van Pelt JF, Yap SH.

Biopharm Drug Dispos. 2000 Dec;21(9):353-64.

PMID:
11523064
17.

In vitro inhibitory effects of Kampo medicines on metabolic reactions catalyzed by human liver microsomes.

Takahashi K, Uejima E, Morisaki T, Takahashi K, Kurokawa N, Azuma J.

J Clin Pharm Ther. 2003 Aug;28(4):319-27.

PMID:
12911685
18.

In vitro modulatory effects on three major human cytochrome P450 enzymes by multiple active constituents and extracts of Centella asiatica.

Pan Y, Abd-Rashid BA, Ismail Z, Ismail R, Mak JW, Pook PC, Er HM, Ong CE.

J Ethnopharmacol. 2010 Jul 20;130(2):275-83. doi: 10.1016/j.jep.2010.05.002. Epub 2010 May 8.

PMID:
20457244
19.

Inhibitory effects of Hwang-Ryun-Hae-Dok-Tang on cytochrome P450 in human liver microsomes.

Lee SY, Jang H, Lee JY, Ma JY, Oh SJ, Kim SK.

Xenobiotica. 2015 Feb;45(2):131-8. doi: 10.3109/00498254.2014.953624. Epub 2014 Aug 22.

PMID:
25145883
20.

Effects of eupatilin and jaceosidin on cytochrome p450 enzyme activities in human liver microsomes.

Ji HY, Kim SY, Kim DK, Jeong JH, Lee HS.

Molecules. 2010 Sep 16;15(9):6466-75. doi: 10.3390/molecules15096466.

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