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Items: 1 to 20 of 173


A role for actin arcs in the leading-edge advance of migrating cells.

Burnette DT, Manley S, Sengupta P, Sougrat R, Davidson MW, Kachar B, Lippincott-Schwartz J.

Nat Cell Biol. 2011 Apr;13(4):371-81. doi: 10.1038/ncb2205. Epub 2011 Mar 20.


Building the actin cytoskeleton: filopodia contribute to the construction of contractile bundles in the lamella.

Nemethova M, Auinger S, Small JV.

J Cell Biol. 2008 Mar 24;180(6):1233-44. doi: 10.1083/jcb.200709134.


Distinction at the leading edge of the cell.

Timpson P, Daly RJ.

Bioessays. 2005 Apr;27(4):349-52.


Two distinct actin networks drive the protrusion of migrating cells.

Ponti A, Machacek M, Gupton SL, Waterman-Storer CM, Danuser G.

Science. 2004 Sep 17;305(5691):1782-6.


Cofilin activity downstream of Pak1 regulates cell protrusion efficiency by organizing lamellipodium and lamella actin networks.

Delorme V, Machacek M, DerMardirossian C, Anderson KL, Wittmann T, Hanein D, Waterman-Storer C, Danuser G, Bokoch GM.

Dev Cell. 2007 Nov;13(5):646-62.


The comings and goings of actin: coupling protrusion and retraction in cell motility.

Small JV, Resch GP.

Curr Opin Cell Biol. 2005 Oct;17(5):517-23. Review.


Comparative dynamics of retrograde actin flow and focal adhesions: formation of nascent adhesions triggers transition from fast to slow flow.

Alexandrova AY, Arnold K, Schaub S, Vasiliev JM, Meister JJ, Bershadsky AD, Verkhovsky AB.

PLoS One. 2008 Sep 18;3(9):e3234. doi: 10.1371/journal.pone.0003234.


Membrane tension controls adhesion positioning at the leading edge of cells.

Pontes B, Monzo P, Gole L, Le Roux AL, Kosmalska AJ, Tam ZY, Luo W, Kan S, Viasnoff V, Roca-Cusachs P, Tucker-Kellogg L, Gauthier NC.

J Cell Biol. 2017 Sep 4;216(9):2959-2977. doi: 10.1083/jcb.201611117. Epub 2017 Jul 7.


Protrusion and actin assembly are coupled to the organization of lamellar contractile structures.

Lim JI, Sabouri-Ghomi M, Machacek M, Waterman CM, Danuser G.

Exp Cell Res. 2010 Aug 1;316(13):2027-41. doi: 10.1016/j.yexcr.2010.04.011. Epub 2010 Apr 18.


Cell migration without a lamellipodium: translation of actin dynamics into cell movement mediated by tropomyosin.

Gupton SL, Anderson KL, Kole TP, Fischer RS, Ponti A, Hitchcock-DeGregori SE, Danuser G, Fowler VM, Wirtz D, Hanein D, Waterman-Storer CM.

J Cell Biol. 2005 Feb 14;168(4):619-31.


Lamellipodial actin mechanically links myosin activity with adhesion-site formation.

Giannone G, Dubin-Thaler BJ, Rossier O, Cai Y, Chaga O, Jiang G, Beaver W, Döbereiner HG, Freund Y, Borisy G, Sheetz MP.

Cell. 2007 Feb 9;128(3):561-75.


Role of focal adhesions and mechanical stresses in the formation and progression of the lamellipodium-lamellum interface [corrected].

Shemesh T, Verkhovsky AB, Svitkina TM, Bershadsky AD, Kozlov MM.

Biophys J. 2009 Sep 2;97(5):1254-64. doi: 10.1016/j.bpj.2009.05.065. Erratum in: Biophys J. 2009 Oct 7;97(7):2115.


Structure and dynamics of an Arp2/3 complex-independent component of the lamellipodial actin network.

Henson JH, Cheung D, Fried CA, Shuster CB, McClellan MK, Voss MK, Sheridan JT, Oldenbourg R.

Cell Motil Cytoskeleton. 2009 Sep;66(9):679-92. doi: 10.1002/cm.20398.


The FAK-Arp2/3 interaction promotes leading edge advance and haptosensing by coupling nascent adhesions to lamellipodia actin.

Swaminathan V, Fischer RS, Waterman CM.

Mol Biol Cell. 2016 Apr 1;27(7):1085-100. doi: 10.1091/mbc.E15-08-0590. Epub 2016 Feb 3.


On the mechanisms of cortical actin flow and its role in cytoskeletal organisation of fibroblasts.

Heath JP, Holifield BF.

Symp Soc Exp Biol. 1993;47:35-56. Review.


mDia2 regulates actin and focal adhesion dynamics and organization in the lamella for efficient epithelial cell migration.

Gupton SL, Eisenmann K, Alberts AS, Waterman-Storer CM.

J Cell Sci. 2007 Oct 1;120(Pt 19):3475-87. Epub 2007 Sep 12.


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