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Items: 1 to 20 of 172

1.

A long noncoding RNA maintains active chromatin to coordinate homeotic gene expression.

Wang KC, Yang YW, Liu B, Sanyal A, Corces-Zimmerman R, Chen Y, Lajoie BR, Protacio A, Flynn RA, Gupta RA, Wysocka J, Lei M, Dekker J, Helms JA, Chang HY.

Nature. 2011 Apr 7;472(7341):120-4. doi: 10.1038/nature09819. Epub 2011 Mar 20.

2.

Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs.

Rinn JL, Kertesz M, Wang JK, Squazzo SL, Xu X, Brugmann SA, Goodnough LH, Helms JA, Farnham PJ, Segal E, Chang HY.

Cell. 2007 Jun 29;129(7):1311-23.

3.

Noncoding RNA synthesis and loss of Polycomb group repression accompanies the colinear activation of the human HOXA cluster.

Sessa L, Breiling A, Lavorgna G, Silvestri L, Casari G, Orlando V.

RNA. 2007 Feb;13(2):223-39. Epub 2006 Dec 21.

4.

Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis.

Gupta RA, Shah N, Wang KC, Kim J, Horlings HM, Wong DJ, Tsai MC, Hung T, Argani P, Rinn JL, Wang Y, Brzoska P, Kong B, Li R, West RB, van de Vijver MJ, Sukumar S, Chang HY.

Nature. 2010 Apr 15;464(7291):1071-6. doi: 10.1038/nature08975.

5.

Global analysis of H3K4 methylation defines MLL family member targets and points to a role for MLL1-mediated H3K4 methylation in the regulation of transcriptional initiation by RNA polymerase II.

Wang P, Lin C, Smith ER, Guo H, Sanderson BW, Wu M, Gogol M, Alexander T, Seidel C, Wiedemann LM, Ge K, Krumlauf R, Shilatifard A.

Mol Cell Biol. 2009 Nov;29(22):6074-85. doi: 10.1128/MCB.00924-09. Epub 2009 Aug 24.

6.

Analysis of dynamic changes in retinoid-induced transcription and epigenetic profiles of murine Hox clusters in ES cells.

De Kumar B, Parrish ME, Slaughter BD, Unruh JR, Gogol M, Seidel C, Paulson A, Li H, Gaudenz K, Peak A, McDowell W, Fleharty B, Ahn Y, Lin C, Smith E, Shilatifard A, Krumlauf R.

Genome Res. 2015 Aug;25(8):1229-43. doi: 10.1101/gr.184978.114. Epub 2015 May 29.

7.

The long non-coding RNA HOTTIP enhances pancreatic cancer cell proliferation, survival and migration.

Cheng Y, Jutooru I, Chadalapaka G, Corton JC, Safe S.

Oncotarget. 2015 May 10;6(13):10840-52.

8.

Exploring CTCF and cohesin related chromatin architecture at HOXA gene cluster in primary human fibroblasts.

Wang X, Xu M, Zhao G, Liu G, Hao D, Lv X, Liu D.

Sci China Life Sci. 2015 Sep;58(9):860-6. doi: 10.1007/s11427-015-4913-5. Epub 2015 Sep 16.

PMID:
26376810
9.

A unique chromatin signature uncovers early developmental enhancers in humans.

Rada-Iglesias A, Bajpai R, Swigut T, Brugmann SA, Flynn RA, Wysocka J.

Nature. 2011 Feb 10;470(7333):279-83. doi: 10.1038/nature09692. Epub 2010 Dec 15.

10.

Clustered ChIP-Seq-defined transcription factor binding sites and histone modifications map distinct classes of regulatory elements.

Rye M, Sætrom P, Håndstad T, Drabløs F.

BMC Biol. 2011 Nov 24;9:80. doi: 10.1186/1741-7007-9-80.

11.

Psip1/p52 regulates posterior Hoxa genes through activation of lncRNA Hottip.

Pradeepa MM, McKenna F, Taylor GC, Bengani H, Grimes GR, Wood AJ, Bhatia S, Bickmore WA.

PLoS Genet. 2017 Apr 6;13(4):e1006677. doi: 10.1371/journal.pgen.1006677. eCollection 2017 Apr.

12.

Epigenetic temporal control of mouse Hox genes in vivo.

Soshnikova N, Duboule D.

Science. 2009 Jun 5;324(5932):1320-3. doi: 10.1126/science.1171468.

13.

WDR5 associates with histone H3 methylated at K4 and is essential for H3 K4 methylation and vertebrate development.

Wysocka J, Swigut T, Milne TA, Dou Y, Zhang X, Burlingame AL, Roeder RG, Brivanlou AH, Allis CD.

Cell. 2005 Jun 17;121(6):859-72.

14.

Cdx is crucial for the timing mechanism driving colinear Hox activation and defines a trunk segment in the Hox cluster topology.

Neijts R, Amin S, van Rooijen C, Deschamps J.

Dev Biol. 2017 Feb 15;422(2):146-154. doi: 10.1016/j.ydbio.2016.12.024. Epub 2016 Dec 29.

15.

Mammalian ASH1L is a histone methyltransferase that occupies the transcribed region of active genes.

Gregory GD, Vakoc CR, Rozovskaia T, Zheng X, Patel S, Nakamura T, Canaani E, Blobel GA.

Mol Cell Biol. 2007 Dec;27(24):8466-79. Epub 2007 Oct 8.

16.

A histone H3 lysine 27 demethylase regulates animal posterior development.

Lan F, Bayliss PE, Rinn JL, Whetstine JR, Wang JK, Chen S, Iwase S, Alpatov R, Issaeva I, Canaani E, Roberts TM, Chang HY, Shi Y.

Nature. 2007 Oct 11;449(7163):689-94. Epub 2007 Sep 12.

PMID:
17851529
17.

Quiescence-induced LncRNAs trigger H4K20 trimethylation and transcriptional silencing.

Bierhoff H, Dammert MA, Brocks D, Dambacher S, Schotta G, Grummt I.

Mol Cell. 2014 May 22;54(4):675-82. doi: 10.1016/j.molcel.2014.03.032. Epub 2014 Apr 24.

18.

Formation of an active tissue-specific chromatin domain initiated by epigenetic marking at the embryonic stem cell stage.

Szutorisz H, Canzonetta C, Georgiou A, Chow CM, Tora L, Dillon N.

Mol Cell Biol. 2005 Mar;25(5):1804-20.

19.

HoxBlinc RNA Recruits Set1/MLL Complexes to Activate Hox Gene Expression Patterns and Mesoderm Lineage Development.

Deng C, Li Y, Zhou L, Cho J, Patel B, Terada N, Li Y, Bungert J, Qiu Y, Huang S.

Cell Rep. 2016 Jan 5;14(1):103-14. doi: 10.1016/j.celrep.2015.12.007. Epub 2015 Dec 24.

20.

Epigenetic mechanisms and boundaries in the regulation of mammalian Hox clusters.

Srivastava S, Dhawan J, Mishra RK.

Mech Dev. 2015 Nov;138 Pt 2:160-9. doi: 10.1016/j.mod.2015.07.015. Epub 2015 Aug 6.

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